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1 February 2014
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Cover Image
Cover Image
The cover shows a section of pelvic lymph node metastasis from a patient with prostate cancer. The double immunostaining with antibodies to visualize the Ki-67 proliferation antigen (fuchsia) and interleukin-30 (brown) shows a low proliferation rate in metastatic cancer cells lacking interleukin-30 expression. For details, see the article by Di Meo and colleagues on page 585 of this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Statistics in Clinical Cancer Research
Molecular Pathways
Review
Human Cancer Biology
Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma
Marie Cumberbatch; Ximing Tang; Garry Beran; Sonia Eckersley; Xin Wang; Rebecca P.A. Ellston; Simon Dearden; Sabina Cosulich; Paul D. Smith; Carmen Behrens; Edward S. Kim; Xinying Su; Shuqiong Fan; Neil Gray; David P. Blowers; Ignacio I. Wistuba; Chris Womack
The Disparate Twins: A Comparative Study of CXCR4 and CXCR7 in SDF-1α–Induced Gene Expression, Invasion and Chemosensitivity of Colon Cancer
Doreen Heckmann; Patrick Maier; Stephanie Laufs; Li Li; Jonathan P. Sleeman; Marcus J. Trunk; Jörg H. Leupold; Frederik Wenz; W. Jens Zeller; Stefan Fruehauf; Heike Allgayer
Cancer Therapy: Preclinical
Randomized, Placebo-Controlled, Double-Blinded Chemoimmunotherapy Clinical Trial in a Pet Dog Model of Diffuse Large B-cell Lymphoma
Laura Marconato; Patrick Frayssinet; Nicole Rouquet; Stefano Comazzi; Vito Ferdinando Leone; Paola Laganga; Federica Rossi; Massimo Vignoli; Lorenzo Pezzoli; Luca Aresu
Imaging, Diagnosis, Prognosis
MUC4-Mediated Regulation of Acute Phase Protein Lipocalin 2 through HER2/AKT/NF-κB Signaling in Pancreatic Cancer
Sukhwinder Kaur; Neil Sharma; Shiv Ram Krishn; Imay Lakshmanan; Satyanarayana Rachagani; Michael J. Baine; Lynette M. Smith; Subodh M. Lele; Aaron R. Sasson; Sushovan Guha; Kavita Mallya; Judy M. Anderson; Michael A. Hollingsworth; Surinder K. Batra
A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer
Dong-Joo Cheon; Yunguang Tong; Myung-Shin Sim; Judy Dering; Dror Berel; Xiaojiang Cui; Jenny Lester; Jessica A. Beach; Mourad Tighiouart; Ann E. Walts; Beth Y. Karlan; Sandra Orsulic
Cancer Therapy: Clinical
Predictive Biomarkers and Personalized Medicine
Quantitative ER and PgR Assessment as Predictors of Benefit from Lapatinib in Postmenopausal Women with Hormone Receptor–Positive, HER2-Negative Metastatic Breast Cancer
Richard S. Finn; Michael F. Press; Judy Dering; Lisa O'Rourke; Allison Florance; Catherine Ellis; Anne-Marie Martin; Stephen Johnston
PIK3CA, BRAF, and PTEN Status and Benefit from Cetuximab in the Treatment of Advanced Colorectal Cancer—Results from NCIC CTG/AGITG CO.17
Christos S. Karapetis; Derek Jonker; Manijeh Daneshmand; Jennifer E. Hanson; Christopher J. O'Callaghan; Celia Marginean; John R. Zalcberg; John Simes; Malcolm J. Moore; Niall C. Tebbutt; Timothy J. Price; Jeremy D. Shapiro; Nick Pavlakis; Peter Gibbs; Guy A. Van Hazel; Ursula Lee; Rashida Haq; Shakeel Virk; Dongsheng Tu; Ian A.J. Lorimer; for the NCIC Clinical Trials Group and the Australasian Gastro-Intestinal Trials Group
Germline and Somatic Mutations in Homologous Recombination Genes Predict Platinum Response and Survival in Ovarian, Fallopian Tube, and Peritoneal Carcinomas
Kathryn P. Pennington; Tom Walsh; Maria I. Harrell; Ming K. Lee; Christopher C. Pennil; Mara H. Rendi; Anne Thornton; Barbara M. Norquist; Silvia Casadei; Alexander S. Nord; Kathy J. Agnew; Colin C. Pritchard; Sheena Scroggins; Rochelle L. Garcia; Mary-Claire King; Elizabeth M. Swisher
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