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1 October 2014
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The cover shows acetylated histone H3 immunohistochemistry staining of skin biopsy at half an hour after the fifth doses of CUDC-101 treatment in the 275-mg/m2 cohort. CUDC-101 induces the accumulation of acetylated histone H3. For details, see the article by Shimizu and colleagues on page 5032 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
Editorial
Policy Statement
CCR Translations
CCR New Strategies
CCR Perspectives in Drug Approval
FDA Approval Summary: Vemurafenib for Treatment of Unresectable or Metastatic Melanoma with the BRAFV600E Mutation
Geoffrey Kim; Amy E. McKee; Yang-Min Ning; Maitreyee Hazarika; Marc Theoret; John R. Johnson; Qiang Casey Xu; Shenghui Tang; Rajeshwari Sridhara; Xiaoping Jiang; Kun He; Donna Roscoe; W. David McGuinn; Whitney S. Helms; Anne Marie Russell; Sarah Pope Miksinski; Jeanne Fourie Zirkelbach; Justin Earp; Qi Liu; Amna Ibrahim; Robert Justice; Richard Pazdur
Molecular Pathways
Cancer Therapy: Clinical
A Recombinant Modified Vaccinia Ankara Vaccine Encoding Epstein–Barr Virus (EBV) Target Antigens: A Phase I Trial in UK Patients with EBV-Positive Cancer
Graham S. Taylor; Hui Jia; Kevin Harrington; Lip Wai Lee; James Turner; Kristin Ladell; David A. Price; Manjit Tanday; Jen Matthews; Claudia Roberts; Ceri Edwards; Lesley McGuigan; Andrew Hartley; Steve Wilson; Edwin P. Hui; Anthony T. C. Chan; Alan B. Rickinson; Neil M. Steven
Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Antonio Omuro; Kathryn Beal; Philip Gutin; Sasan Karimi; Denise D. Correa; Thomas J. Kaley; Lisa M. DeAngelis; Timothy A. Chan; Igor T. Gavrilovic; Craig Nolan; Adilia Hormigo; Andrew B. Lassman; Ingo Mellinghoff; Christian Grommes; Anne S. Reiner; Katherine S. Panageas; Raymond E. Baser; Viviane Tabar; Elena Pentsova; Juan Sanchez; Renata Barradas-Panchal; Jianan Zhang; Geraldine Faivre; Cameron W. Brennan; Lauren E. Abrey; Jason T. Huse
Phase I First-in-Human Study of CUDC-101, a Multitargeted Inhibitor of HDACs, EGFR, and HER2 in Patients with Advanced Solid Tumors
Toshio Shimizu; Patricia M. LoRusso; Kyri P. Papadopoulos; Amita Patnaik; Muralidhar Beeram; Lon S. Smith; Drew W. Rasco; Theresa A. Mays; Glenda Chambers; Anna Ma; Jing Wang; Robert Laliberte; Maurizio Voi; Anthony W. Tolcher
Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303
Ann Marie Egloff; Ju-Whei Lee; Corey J. Langer; Harry Quon; Alec Vaezi; Jennifer R. Grandis; Raja R. Seethala; Lin Wang; Dong M. Shin; Athanassios Argiris; Donghua Yang; Ranee Mehra; John Andrew Ridge; Urjeet A. Patel; Barbara A. Burtness; Arlene A. Forastiere
Personalized Medicine and Imaging
Cancer Therapy: Preclinical
Overexpression of Smad7 Blocks Primary Tumor Growth and Lung Metastasis Development in Osteosarcoma
Audrey Lamora; Julie Talbot; Gwenola Bougras; Jérôme Amiaud; Marion Leduc; Julie Chesneau; Julien Taurelle; Verena Stresing; Marie Cécile Le Deley; Marie Françoise Heymann; Dominique Heymann; Françoise Redini; Franck Verrecchia
Biology of Human Tumors
Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma
Chi Young Ok; Jiayu Chen; Zijun Y. Xu-Monette; Alexandar Tzankov; Ganiraju C. Manyam; Ling Li; Carlo Visco; Santiago Montes-Moreno; Karen Dybkær; April Chiu; Attilio Orazi; Youli Zu; Govind Bhagat; Kristy L. Richards; Eric D. Hsi; William W.L. Choi; J. Han van Krieken; Jooryung Huh; Xiaoying Zhao; Maurilio Ponzoni; Andrés J.M. Ferreri; Francesco Bertoni; John P. Farnen; Michael B. Møller; Miguel A. Piris; Jane N. Winter; L. Jeffrey Medeiros; Ken H. Young
Letters to the Editor
Tumor Stromal Phenotypes Define VEGF Sensitivity—Letter
Gert G. Van den Eynden; Nigel C. Bird; Luc Y. Dirix; Rikke L. Eefsen; Zu-Hua Gao; Gunilla Høyer-Hansen; Martin Illemann; Ali W. Majeed; Peter Metrakos; Andrew R. Reynolds; Ben Vainer; Pieter-Jan van Dam; Steven J. Van Laere; Peter B. Vermeulen; Fernando Vidal-Vanaclocha; Pnina Brodt; for the Liver Metastasis Research Network
Correction
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