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1 November 2013
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Cover Image
Cover Image
The cover shows primary cultures of CAFs from colorectal cancer patients: immunofluorescence analyses for α-SMA expression in human primary colon CAFs from two different patients with low and high α-SMA level. For details, see the article by Herrera and colleagues on page 5914 of this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Issue Sections
Highlights
CCR Translations
CCR New Strategies
CCR Perspectives in Drug Approval
CCR Drug Updates
Molecular Pathways
Perspectives
Review
Human Cancer Biology
Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Zhi-Zhou Shi; Li Shang; Yan-Yi Jiang; Jia-Jie Hao; Yu Zhang; Tong-Tong Zhang; De-Chen Lin; Shu-Guang Liu; Bo-Shi Wang; Ting Gong; Qi-Min Zhan; Ming-Rong Wang
Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features
Fortunato Morabito; Laura Mosca; Giovanna Cutrona; Luca Agnelli; Giacomo Tuana; Manuela Ferracin; Barbara Zagatti; Marta Lionetti; Sonia Fabris; Francesco Maura; Serena Matis; Massimo Gentile; Ernesto Vigna; Monica Colombo; Carlotta Massucco; Anna Grazia Recchia; Sabrina Bossio; Laura De Stefano; Fiorella Ilariucci; Caterina Musolino; Stefano Molica; Francesco Di Raimondo; Agostino Cortelezzi; Pierfrancesco Tassone; Massimo Negrini; Sara Monti; Davide Rossi; Gianluca Gaidano; Manlio Ferrarini; Antonino Neri
Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature
Mercedes Herrera; Abul B.M.M.K. Islam; Alberto Herrera; Paloma Martín; Vanesa García; Javier Silva; Jose M. Garcia; Clara Salas; Ignacio Casal; Antonio García de Herreros; Félix Bonilla; Cristina Peña
Cancer Therapy: Preclinical
Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo
Jane Renshaw; Kathryn R. Taylor; Ryan Bishop; Melanie Valenti; Alexis De Haven Brandon; Sharon Gowan; Suzanne A. Eccles; Ruth R. Ruddle; Louise D. Johnson; Florence I. Raynaud; Joanna L. Selfe; Khin Thway; Torsten Pietsch; Andrew D. Pearson; Janet Shipley
Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer
Dariush Etemadmoghadam; George Au-Yeung; Meaghan Wall; Chris Mitchell; Maya Kansara; Elizabeth Loehrer; Crisoula Batzios; Joshy George; Sarah Ftouni; Barbara A. Weir; Scott Carter; Irma Gresshoff; Linda Mileshkin; Danny Rischin; William C. Hahn; Paul M. Waring; Gad Getz; Carleen Cullinane; Lynda J. Campbell; David D. Bowtell
Imaging, Diagnosis, Prognosis
Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008
Ingrid J.G. Burvenich; Fook T. Lee; Glenn A. Cartwright; Graeme J. O'Keefe; Dahna Makris; Diana Cao; Sylvia Gong; Anderly C. Chueh; John M. Mariadason; Martin W. Brechbiel; Robert A. Beckman; Kosaku Fujiwara; Reinhard von Roemeling; Andrew M. Scott
Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Jie-Yi Shi; Qiang Gao; Zhi-Chao Wang; Jian Zhou; Xiao-Ying Wang; Zhi-Hui Min; Ying-Hong Shi; Guo-Ming Shi; Zhen-Bin Ding; Ai-Wu Ke; Zhi Dai; Shuang-Jian Qiu; Kang Song; Jia Fan
Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Sofia Torres; Rubén A. Bartolomé; Marta Mendes; Rodrigo Barderas; M. Jesús Fernandez-Aceñero; Alberto Peláez-García; Cristina Peña; María Lopez-Lucendo; Roi Villar-Vázquez; Antonio García de Herreros; Felix Bonilla; J. Ignacio Casal
Cancer Therapy: Clinical
Author Choice
A Phase I Study of the HSP90 Inhibitor Retaspimycin Hydrochloride (IPI-504) in Patients with Gastrointestinal Stromal Tumors or Soft-Tissue Sarcomas
Andrew J. Wagner; Rashmi Chugh; Lee S. Rosen; Jeffrey A. Morgan; Suzanne George; Michael Gordon; Joi Dunbar; Emmanuel Normant; David Grayzel; George D. Demetri
Predictive Biomarkers and Personalized Medicine
Variation within 3′-UTRs of Base Excision Repair Genes and Response to Therapy in Colorectal Cancer Patients: A Potential Modulation of microRNAs Binding
Barbara Pardini; Fabio Rosa; Elisa Barone; Cornelia Di Gaetano; Jana Slyskova; Jan Novotny; Miroslav Levy; Sonia Garritano; Ludmila Vodickova; Tomas Buchler; Federica Gemignani; Stefano Landi; Pavel Vodicka; Alessio Naccarati
Letter to the Editor
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale within the United States of Bavencio® (avelumab), a pharmaceutical owned by Merck. If any resulting funds are received, they would not be used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.
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