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1 September 2013
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Colocalization of MDA-9/Syntenin and EGFR in uroepithelial T24 cells. Immunofluorescence analysis demonstrated coexpression of MDA-9/Syntenin (green) and EGFR (red) in the cell membrane and cytoplasm of T24 cells. For details, see the article by Dasgupta and colleagues on page 4621 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
CCR New Strategies
CCR Perspectives in Drug Approval
U.S. Food and Drug Administration Approval: Carfilzomib for the Treatment of Multiple Myeloma
Thomas M. Herndon; Albert Deisseroth; Edvardas Kaminskas; Robert C. Kane; Kallappa M. Koti; Mark D. Rothmann; Bahru Habtemariam; Julie Bullock; Jeffrey D. Bray; Jessica Hawes; Todd R. Palmby; Josephine Jee; William Adams; Houda Mahayni; Janice Brown; Angelica Dorantes; Rajeshwari Sridhara; Ann T. Farrell; Richard Pazdur
Molecular Pathways
Reviews
Human Cancer Biology
BRAF/NRAS Wild-Type Melanomas Have a High Mutation Load Correlating with Histologic and Molecular Signatures of UV Damage
Victoria J. Mar; Stephen Q. Wong; Jason Li; Richard A. Scolyer; Catriona McLean; Anthony T. Papenfuss; Richard W. Tothill; Hojabr Kakavand; Graham J. Mann; John F. Thompson; Andreas Behren; Jonathan S. Cebon; Rory Wolfe; John W. Kelly; Alexander Dobrovic; Grant A. McArthur
The Translocation t(4;14) Can Be Present Only in Minor Subclones in Multiple Myeloma
Benjamin Hébraud; Denis Caillot; Jill Corre; Gérald Marit; Cyrille Hulin; Xavier Leleu; Laurence Lodé; Marc Wetterwald; Mamoun Dib; Philippe Rodon; Laurent Voillat; Bruno Royer; Eric Voog; Olivier Fitoussi; Anne-Marie Stoppa; Laurent Garderet; Brigitte Kolb; Michel Maigre; Nadine Boullanger; Olivier Allangba; Lionel Karlin; Nicolas Daguindau; Laurence Legros; Claudine Sohn; Marie-Véronique Joubert; Pascal Lenain; Thierry Facon; Michel Attal; Philippe Moreau; Hervé Avet-Loiseau
Author Choice
microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2
Wen-Ting Liao; Ting-Ting Li; Zheng-Gen Wang; Shu-Yang Wang; Mei-Rong He; Ya-Ping Ye; Lu Qi; Yan-Mei Cui; Ping Wu; Hong-Li Jiao; Chi Zhang; Yi-Jun Xie; Jun-Xian Wang; Yan-Qing Ding
Genomic Heterogeneity of Translocation Renal Cell Carcinoma
Gabriel G. Malouf; Federico A. Monzon; Jérôme Couturier; Vincent Molinié; Bernard Escudier; Philippe Camparo; Xiaoping Su; Hui Yao; Pheroze Tamboli; Dolores Lopez-Terrada; Maria Picken; Marileila Garcia; Asha S. Multani; Sen Pathak; Christopher G. Wood; Nizar M. Tannir
Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets
Steven J. Van Laere; Naoto T. Ueno; Pascal Finetti; Peter Vermeulen; Anthony Lucci; Fredika M. Robertson; Melike Marsan; Takayuki Iwamoto; Savitri Krishnamurthy; Hiroko Masuda; Peter van Dam; Wendy A. Woodward; Patrice Viens; Massimo Cristofanilli; Daniel Birnbaum; Luc Dirix; James M. Reuben; François Bertucci
Cancer Therapy: Preclinical
Construction of an Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Targeting EGFRwt and EGFRvIII for Brain Tumor Therapy
Vidyalakshmi Chandramohan; Xuhui Bao; Stephen T. Keir; Charles N. Pegram; Scott E. Szafranski; Hailan Piao; Carol J. Wikstrand; Roger E. McLendon; Chien-Tsun Kuan; Ira H. Pastan; Darell D. Bigner
Imaging, Diagnosis, Prognosis
A 3-Plex Methylation Assay Combined with the FGFR3 Mutation Assay Sensitively Detects Recurrent Bladder Cancer in Voided Urine
Raju Kandimalla; Roy Masius; Willemien Beukers; Chris H. Bangma; Torben F. Orntoft; Lars Dyrskjot; Nikki van Leeuwen; Hester Lingsma; Angela A.G. van Tilborg; Ellen C. Zwarthoff
Cancer Therapy: Clinical
Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
Michal J. Besser; Ronnie Shapira-Frommer; Orit Itzhaki; Avraham J. Treves; Douglas B. Zippel; Daphna Levy; Adva Kubi; Noa Shoshani; Dragoslav Zikich; Yaara Ohayon; Daniel Ohayon; Bruria Shalmon; Gal Markel; Ronit Yerushalmi; Sara Apter; Alon Ben-Nun; Eytan Ben-Ami; Avichai Shimoni; Arnon Nagler; Jacob Schachter
A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Cheryl Lai-Lai Chiang; Lana E. Kandalaft; Janos Tanyi; Andrea R. Hagemann; Gregory T. Motz; Nikolaos Svoronos; Kathleen Montone; Gina M. Mantia-Smaldone; Lori Smith; Harvey L. Nisenbaum; Bruce L. Levine; Michael Kalos; Brian J. Czerniecki; Drew A. Torigian; Daniel J. Powell, Jr; Rosemarie Mick; George Coukos
Phase II Study of Bevacizumab in Combination with Sorafenib in Recurrent Glioblastoma (N0776): A North Central Cancer Treatment Group Trial
Evanthia Galanis; S. Keith Anderson; Jackie M. Lafky; Joon H. Uhm; Caterina Giannini; Shaji K. Kumar; Teresa K. Kimlinger; Donald W. Northfelt; Patrick J. Flynn; Kurt A. Jaeckle; Timothy J. Kaufmann; Jan C. Buckner
Phase I Study of BIIB028, a Selective Heat Shock Protein 90 Inhibitor, in Patients with Refractory Metastatic or Locally Advanced Solid Tumors
David Hong; Rabih Said; Gerald Falchook; Aung Naing; Stacy Moulder; Apostolia-Maria Tsimberidou; Gerald Galluppi; Naveen Dakappagari; Chris Storgard; Razelle Kurzrock; Lee S. Rosen
Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors
Cristiana Sessa; Patricia Lorusso; Anthony Tolcher; Françoise Farace; Nathalie Lassau; Angelo Delmonte; Antonio Braghetti; Rastislav Bahleda; Patrick Cohen; Marie Hospitel; Christine Veyrat-Follet; Jean-Charles Soria
Predictive Biomarkers and Personalized Medicine
Detection of Mutant Free Circulating Tumor DNA in the Plasma of Patients with Gastrointestinal Stromal Tumor Harboring Activating Mutations of CKIT or PDGFRA
Jacqueline Maier; Thoralf Lange; Irina Kerle; Katja Specht; Melanie Bruegel; Claudia Wickenhauser; Philipp Jost; Dietger Niederwieser; Christian Peschel; Justus Duyster; Nikolas von Bubnoff
Tumor Genetic Analyses of Patients with Metastatic Melanoma Treated with the BRAF Inhibitor Dabrafenib (GSK2118436)
Katherine L. Nathanson; Anne-Marie Martin; Bradley Wubbenhorst; Joel Greshock; Richard Letrero; Kurt D'Andrea; Steven O'Day; Jeffrey R. Infante; Gerald S. Falchook; Hendrik-Tobias Arkenau; Michael Millward; Michael P. Brown; Anna Pavlick; Michael A. Davies; Bo Ma; Robert Gagnon; Martin Curtis; Peter F. Lebowitz; Richard Kefford; Georgina V. Long
A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer
Amanda Eustace; Navin Mani; Paul N. Span; Joely J. Irlam; Janet Taylor; Guy N.J. Betts; Helen Denley; Crispin J. Miller; Jarrod J. Homer; Ana M. Rojas; Peter J. Hoskin; Francesca M. Buffa; Adrian L. Harris; Johannes H.A.M. Kaanders; Catharine M.L. West
Author Choice
Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Jerry Usary; Wei Zhao; David Darr; Patrick J. Roberts; Mei Liu; Lorraine Balletta; Olga Karginova; Jamie Jordan; Austin Combest; Arlene Bridges; Aleix Prat; Maggie C. U. Cheang; Jason I. Herschkowitz; Jeffrey M. Rosen; William Zamboni; Norman E. Sharpless; Charles M. Perou
Retractions
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