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15 June 2013
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Cover Image
Cover Image
The cover shows a section of a lymph node biopsy from a patient with chronic lymphocytic leukemia. Immunohistochemical staining shows strong phospho-eIF4E expression within a proliferation center suggesting induction of cap complex formation and protein synthesis within this microenvironment. For details, see the article by Willimott and colleagues on page 3212 of this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Molecular Pathways
Human Cancer Biology
microRNA Expression Profiles Identify Subtypes of Mantle Cell Lymphoma with Different Clinicobiological Characteristics
Alba Navarro; Guillem Clot; Miriam Prieto; Cristina Royo; Maria Carmela Vegliante; Virginia Amador; Elena Hartmann; Itziar Salaverria; Sílvia Beà; Jose Ignacio Martín-Subero; Andreas Rosenwald; German Ott; Adrian Wiestner; Wyndham H. Wilson; Elías Campo; Luis Hernández
Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
Marta Lionetti; Pellegrino Musto; Maria Teresa Di Martino; Sonia Fabris; Luca Agnelli; Katia Todoerti; Giacomo Tuana; Laura Mosca; Maria E. Gallo Cantafio; Vitina Grieco; Gabriella Bianchino; Fiorella D'Auria; Teodora Statuto; Carmela Mazzoccoli; Luciana De Luca; Maria Teresa Petrucci; Massimo Offidani; Francesco Di Raimondo; Antonietta Falcone; Tommaso Caravita; Paola Omede'; Fortunato Morabito; Pierfrancesco Tassone; Mario Boccadoro; Antonio Palumbo; Antonino Neri
Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas
Klaus G. Griewank; Henrike Westekemper; Rajmohan Murali; Monika Mach; Bastian Schilling; Thomas Wiesner; Tobias Schimming; Elisabeth Livingstone; Antje Sucker; Florian Grabellus; Claudia Metz; Daniela Süsskind; Uwe Hillen; Michael R. Speicher; Scott E. Woodman; Klaus-Peter Steuhl; Dirk Schadendorf
Cancer Therapy: Preclinical
ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation
Laura Biddlestone-Thorpe; Muhammad Sajjad; Elizabeth Rosenberg; Jason M. Beckta; Nicholas C.K. Valerie; Mary Tokarz; Bret R. Adams; Alison F. Wagner; Ashraf Khalil; Donna Gilfor; Sarah E. Golding; Sumitra Deb; David G. Temesi; Alan Lau; Mark J. O'Connor; Kevin S. Choe; Luis F. Parada; Sang Kyun Lim; Nitai D. Mukhopadhyay; Kristoffer Valerie
Frequent Inactivation of Cysteine Dioxygenase Type 1 Contributes to Survival of Breast Cancer Cells and Resistance to Anthracyclines
Jana Jeschke; Heather M. O'Hagan; Wei Zhang; Rajita Vatapalli; Marilia Freitas Calmon; Ludmila Danilova; Claudia Nelkenbrecher; Leander Van Neste; Ingrid T.G.W. Bijsmans; Manon Van Engeland; Edward Gabrielson; Kornel E. Schuebel; Andreas Winterpacht; Stephen B. Baylin; James G. Herman; Nita Ahuja
Monoclonal Antibody against the Ectodomain of E-Cadherin (DECMA-1) Suppresses Breast Carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP Pathways
Sabine M. Brouxhon; Stephanos Kyrkanides; Xiaofei Teng; Veena Raja; M. Kerry O'Banion; Robert Clarke; Stephen Byers; Andrew Silberfeld; Carmen Tornos; Li Ma
Imaging, Diagnosis, Prognosis
Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Katia Todoerti; Luca Agnelli; Sonia Fabris; Marta Lionetti; Giacomo Tuana; Laura Mosca; Luigia Lombardi; Vitina Grieco; Gabriella Bianchino; Fiorella D'Auria; Teodora Statuto; Carmela Mazzoccoli; Luciana De Luca; Maria Teresa Petrucci; Fortunato Morabito; Massimo Offidani; Francesco Di Raimondo; Antonietta Falcone; Paola Omede'; Pierfrancesco Tassone; Mario Boccadoro; Antonio Palumbo; Antonino Neri; Pellegrino Musto
Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
A. Ari Hakimi; Irina Ostrovnaya; Boris Reva; Nikolaus Schultz; Ying-Bei Chen; Mithat Gonen; Han Liu; Shugaku Takeda; Martin H. Voss; Satish K. Tickoo; Victor E. Reuter; Paul Russo; Emily H. Cheng; Chris Sander; Robert J. Motzer; James J. Hsieh; for The ccRCC Cancer Genome Atlas (KIRC TCGA) Research Network investigators
EDNRB and DCC Salivary Rinse Hypermethylation Has a Similar Performance as Expert Clinical Examination in Discrimination of Oral Cancer/Dysplasia versus Benign Lesions
Juliana Schussel; Xian Chong Zhou; Zhe Zhang; Kavita Pattani; Francisco Bermudez; Germain Jean-Charles; Thomas McCaffrey; Tapan Padhya; Joan Phelan; Silvia Spivakovsky; Mariana Brait; Ryan Li; Helen Yoo Bowne; Judith D. Goldberg; Linda Rolnitzky; Miriam Robbins; A. Ross Kerr; David Sirois; Joseph A. Califano
PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer
Fiona L. Day; Robert N. Jorissen; Lara Lipton; Dmitri Mouradov; Anuratha Sakthianandeswaren; Michael Christie; Shan Li; Cary Tsui; Jeannie Tie; Jayesh Desai; Zheng-Zhou Xu; Peter Molloy; Vicki Whitehall; Barbara A. Leggett; Ian T. Jones; Stephen McLaughlin; Robyn L. Ward; Nicholas J. Hawkins; Andrew R. Ruszkiewicz; James Moore; Dana Busam; Qi Zhao; Robert L. Strausberg; Peter Gibbs; Oliver M. Sieber
Cancer Therapy: Clinical
Prospective Phase II Study on 5-Days Azacitidine for Treatment of Symptomatic and/or Erythropoietin Unresponsive Patients with Low/INT-1–Risk Myelodysplastic Syndromes
Carla Filì; Michele Malagola; Matilde Y. Follo; Carlo Finelli; Ilaria Iacobucci; Giovanni Martinelli; Federica Cattina; Cristina Clissa; Anna Candoni; Renato Fanin; Marco Gobbi; Monica Bocchia; Marzia Defina; Pierangelo Spedini; Cristina Skert; Lucia Manzoli; Lucio Cocco; Domenico Russo
Predictive Biomarkers and Personalized Medicine
CYP3A4*22 Genotype and Systemic Exposure Affect Paclitaxel-Induced Neurotoxicity
Anne-Joy M. de Graan; Laure Elens; Jason A. Sprowl; Alex Sparreboom; Lena E. Friberg; Bronno van der Holt; Pleun J. de Raaf; Peter de Bruijn; Frederike K. Engels; Ferry A.L.M. Eskens; Erik A.C. Wiemer; Jaap Verweij; Ron H.J. Mathijssen; Ron H.N. van Schaik
Letters to the Editor
Retraction
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