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1 February 2012
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A section of endometrial tumor xenografted in a mouse injected with Wi38 fibroblasts that fail to support tumor vascularization. Immunofluorescence analysis with antibodies against CD31 (green) and Ki67 (red) shows lack of CD31-positive vasculature and Ki67-positive proliferating cells exclusively in the peripheral tumor layer (bottom), whereas injection of omental adipose stromal cells increases tumor proliferation and vascularization. For details, see the article by Klopp and colleagues on page 771 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Molecular Pathways
CCR Focus
Review
Human Cancer Biology
Modeling a Lethal Prostate Cancer Variant with Small-Cell Carcinoma Features
Vassiliki Tzelepi; Jiexin Zhang; Jing-Fang Lu; Brittany Kleb; Guanglin Wu; Xinhai Wan; Anh Hoang; Eleni Efstathiou; Kanishka Sircar; Nora M. Navone; Patricia Troncoso; Shoudan Liang; Christopher J. Logothetis; Sankar N. Maity; Ana M. Aparicio
Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment
Joost S. Vermaat; Isaac J. Nijman; Marco J. Koudijs; Frank L. Gerritse; Stefan J. Scherer; Michal Mokry; Wijnand M. Roessingh; Nico Lansu; Ewart de Bruijn; Richard van Hillegersberg; Paul J. van Diest; Edwin Cuppen; Emile E. Voest
MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
Cristina Migliore; Valentina Martin; Vera P. Leoni; Angelo Restivo; Luigi Atzori; Annalisa Petrelli; Claudio Isella; Luigi Zorcolo; Ivana Sarotto; Giuseppe Casula; Paolo M. Comoglio; Amedeo Columbano; Silvia Giordano
Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways
Neerav Shukla; Nabahet Ameur; Ismail Yilmaz; Khedoudja Nafa; Chyau-Yueh Lau; Angela Marchetti; Laetitia Borsu; Frederic G. Barr; Marc Ladanyi
Cancer Therapy: Preclinical
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy
Roberto Tonelli; Alan McIntyre; Consuelo Camerin; Zoë S. Walters; Korinne Di Leo; Joanna Selfe; Stefania Purgato; Edoardo Missiaglia; Andrea Tortori; Jane Renshaw; Annalisa Astolfi; Kathryn R. Taylor; Salvatore Serravalle; Ryan Bishop; Cristina Nanni; Linda J. Valentijn; Andrea Faccini; Ivo Leuschner; Serena Formica; Jorge S. Reis-Filho; Valentina Ambrosini; Khin Thway; Monica Franzoni; Brenda Summersgill; Rosangela Marchelli; Patrizia Hrelia; Giorgio Cantelli-Forti; Stefano Fanti; Roberto Corradini; Andrea Pession; Janet Shipley
Imaging, Diagnosis, Prognosis
External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses
Caroline Van Holsbeke; Ben Van Calster; Tom Bourne; Silvia Ajossa; Antonia C. Testa; Stefano Guerriero; Robert Fruscio; Andrea Alberto Lissoni; Artur Czekierdowski; Luca Savelli; Sabine Van Huffel; Lil Valentin; Dirk Timmerman
Mitotic Checkpoints and Chromosome Instability Are Strong Predictors of Clinical Outcome in Gastrointestinal Stromal Tumors
Pauline Lagarde; Gaëlle Pérot; Audrey Kauffmann; Céline Brulard; Valérie Dapremont; Isabelle Hostein; Agnès Neuville; Agnieszka Wozniak; Raf Sciot; Patrick Schöffski; Alain Aurias; Jean-Michel Coindre; Maria Debiec-Rychter; Frédéric Chibon
Pharmacokinetically Stabilized Cystine Knot Peptides That Bind Alpha-v-Beta-6 Integrin with Single-Digit Nanomolar Affinities for Detection of Pancreatic Cancer
Richard H. Kimura; Robert Teed; Benjamin J. Hackel; Marybeth A. Pysz; Courtney Z. Chuang; Ataya Sathirachinda; Jürgen K. Willmann; Sanjiv S. Gambhir
Tumor Infiltration by T Lymphocytes Expressing Chemokine Receptor 7 (CCR7) Is Predictive of Favorable Outcome in Patients with Advanced Colorectal Carcinoma
Pierpaolo Correale; Maria Saveria Rotundo; Cirino Botta; Maria Teresa Del Vecchio; Chiara Ginanneschi; Antonella Licchetta; Raffaele Conca; Serena Apollinari; Fabio De Luca; Pierfrancesco Tassone; Pierosandro Tagliaferri
Cancer Therapy: Clinical
A Live-Attenuated Listeria Vaccine (ANZ-100) and a Live-Attenuated Listeria Vaccine Expressing Mesothelin (CRS-207) for Advanced Cancers: Phase I Studies of Safety and Immune Induction
Dung T. Le; Dirk G. Brockstedt; Ran Nir-Paz; Johannes Hampl; Shruti Mathur; John Nemunaitis; Daniel H. Sterman; Raffit Hassan; Eric Lutz; Bentley Moyer; Martin Giedlin; Jana-Lynn Louis; Elizabeth A. Sugar; Alice Pons; Andrea L. Cox; Jordana Levine; Aimee Luck Murphy; Peter Illei; Thomas W. Dubensky, Jr; Joseph E. Eiden; Elizabeth M. Jaffee; Daniel A. Laheru
Predictive Biomarkers and Personalized Medicine
Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer
Vincent A. de Weger; Annelies W. Turksma; Quirinus J.M. Voorham; Zelda Euler; Herman Bril; Alfons J. van den Eertwegh; Elisabeth Bloemena; Herbert M. Pinedo; Jan B. Vermorken; Harm van Tinteren; Gerrit A. Meijer; Erik Hooijberg
Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803
Shuji Ogino; Kaori Shima; Jeffrey A. Meyerhardt; Nadine J. McCleary; Kimmie Ng; Donna Hollis; Leonard B. Saltz; Robert J. Mayer; Paul Schaefer; Renaud Whittom; Alexander Hantel; Al B. Benson, III; Donna Spiegelman; Richard M. Goldberg; Monica M. Bertagnolli; Charles S. Fuchs
Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness
Nyam-Osor Chimge; Sanjeev K. Baniwal; Jingqin Luo; Simon Coetzee; Omar Khalid; Benjamin P. Berman; Debu Tripathy; Matthew J. Ellis; Baruch Frenkel
Letter to the Editor
Correction
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