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1 May 2011
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Cover Image
Cover Image
Fibroblast growth factor receptor 2B (FGFR2) in mouse submandibular glands. Immunofluorescence staining shows the presence of FGFR2 in mouse submandibular glands. FGFR2 staining is shown in red and nuclear staining with DAPI (× 400) is shown in blue. Ductal cells show stronger FGFR2-positive staining than acinar cells. For further details, please see Zheng and coworkers on page 2842 in this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
CCR New Strategies
Molecular Pathways
Human Cancer Biology
Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer
Hue-Kian Oh; Angie Lay-Keng Tan; Kakoli Das; Chia-Huey Ooi; Nian-Tao Deng; Iain BeeHuat Tan; Emmanuel Beillard; Julian Lee; Kalpana Ramnarayanan; Sun-Young Rha; Nallasivam Palanisamy; P. Mathijs Voorhoeve; Patrick Tan
Cancer Therapy: Preclinical
MicroRNA-125a-5p Is an Independent Prognostic Factor in Gastric Cancer and Inhibits the Proliferation of Human Gastric Cancer Cells in Combination with Trastuzumab
Naohiro Nishida; Koshi Mimori; Muller Fabbri; Takehiko Yokobori; Tomoya Sudo; Fumiaki Tanaka; Kohei Shibata; Hideshi Ishii; Yuichiro Doki; Masaki Mori
Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events
Shirin Arastu-Kapur; Janet L. Anderl; Marianne Kraus; Francesco Parlati; Kevin D. Shenk; Susan J. Lee; Tony Muchamuel; Mark K. Bennett; Christoph Driessen; Andrew J. Ball; Christopher J. Kirk
Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization
Elizabeth J. Ilett; Montserrat Bárcena; Fiona Errington-Mais; Stephen Griffin; Kevin J. Harrington; Hardev S. Pandha; Matthew Coffey; Peter J. Selby; Ronald W.A.L. Limpens; Mieke Mommaas; Rob C. Hoeben; Richard G. Vile; Alan A. Melcher
Genz-644282, a Novel Non-Camptothecin Topoisomerase I Inhibitor for Cancer Treatment
Leslie S. Kurtzberg; Stephanie Roth; Roy Krumbholz; Jennifer Crawford; Christy Bormann; Sarah Dunham; Min Yao; Cecile Rouleau; Rebecca G. Bagley; Xian-Jie Yu; Fei Wang; Steven M. Schmid; Edmond J. LaVoie; Beverly A. Teicher
MK-1775, a Potent Wee1 Inhibitor, Synergizes with Gemcitabine to Achieve Tumor Regressions, Selectively in p53-Deficient Pancreatic Cancer Xenografts
N.V. Rajeshkumar; Elizabeth De Oliveira; Niki Ottenhof; James Watters; David Brooks; Tim Demuth; Stuart D. Shumway; Shinji Mizuarai; Hiroshi Hirai; Anirban Maitra; Manuel Hidalgo
Enhanced Safety Profiles of the Telomerase-Specific Replication-Competent Adenovirus by Incorporation of Normal Cell-Specific microRNA-Targeted Sequences
Kumiko Sugio; Fuminori Sakurai; Kazufumi Katayama; Katsuhisa Tashiro; Hayato Matsui; Kenji Kawabata; Atsushi Kawase; Masahiro Iwaki; Takao Hayakawa; Toshiyoshi Fujiwara; Hiroyuki Mizuguchi
Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer
Filippa Pettersson; Christina Yau; Monica C. Dobocan; Biljana Culjkovic-Kraljacic; Hélène Retrouvay; Rachel Puckett; Ludmila M. Flores; Ian E. Krop; Caroline Rousseau; Eftihia Cocolakis; Katherine L. B. Borden; Christopher C. Benz; Wilson H. Miller, Jr.
Imaging, Diagnosis, Prognosis
The Viral Load of Epstein–Barr Virus (EBV) DNA in Peripheral Blood Predicts for Biological and Clinical Characteristics in Hodgkin Lymphoma
Stefan Hohaus; Rosaria Santangelo; Manuela Giachelia; Barbara Vannata; Giuseppina Massini; Annarosa Cuccaro; Maurizio Martini; Valeriana Cesarini; Tonia Cenci; Francesco D'Alo; Maria Teresa Voso; Giovanni Fadda; Giuseppe Leone; Luigi M Larocca
Prediction of Postoperative Recurrence-Free Survival in Non–Small Cell Lung Cancer by Using an Internationally Validated Gene Expression Model
Ranjana Mitra; Jinseon Lee; Jisuk Jo; Monica Milani; Jeanette N. McClintick; Howard J. Edenberg; Kenneth A. Kesler; Karen M. Rieger; Sunil Badve; Oscar W. Cummings; Ahmed Mohiuddin; Dafydd G. Thomas; Xianghua Luo; Beth E. Juliar; Lang Li; Clementina Mesaros; Ian A. Blair; Anjaiah Srirangam; Robert A. Kratzke; Clement J. McDonald; Jhingook Kim; David A. Potter
Comparative Prognostic Value of Epidermal Growth Factor Quantitative Protein Expression Compared with FISH for Head and Neck Squamous Cell Carcinoma
Eirini Pectasides; Theodore Rampias; Panteleimon Kountourakis; Clarence Sasaki; Diane Kowalski; George Fountzilas; Thomas Zaramboukas; David Rimm; Barbara Burtness; Amanda Psyrri
Global Gene Expression Profiling and Validation in Esophageal Squamous Cell Carcinoma and Its Association with Clinical Phenotypes
Hua Su; Nan Hu; Howard H. Yang; Chaoyu Wang; Mikiko Takikita; Quan-Hong Wang; Carol Giffen; Robert Clifford; Stephen M. Hewitt; Jian-Zhong Shou; Alisa M. Goldstein; Maxwell P. Lee; Philip R. Taylor
Persistence of Disseminated Tumor Cells in the Bone Marrow of Breast Cancer Patients Predicts Increased Risk for Relapse—A European Pooled Analysis
Wolfgang Janni; Florian D. Vogl; Gro Wiedswang; Marit Synnestvedt; Tanja Fehm; Julia Jückstock; Elin Borgen; Brigitte Rack; Stephan Braun; Harald Sommer; Erich Solomayer; Klaus Pantel; Jahn Nesland; Klaus Friese; Bjørn Naume
Cancer Therapy: Clinical
Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
Philip C. Amrein; Eyal C. Attar; Tak Takvorian; Ephraim P. Hochberg; Karen K. Ballen; Kathleen M. Leahy; David C. Fisher; Ann S. LaCasce; Eric D. Jacobsen; Philippe Armand; Robert P. Hasserjian; Lillian Werner; Donna Neuberg; Jennifer R. Brown
Intra–Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial
Antoni Ribas; Jeffrey S. Weber; Bartosz Chmielowski; Begonya Comin-Anduix; David Lu; Michael Douek; Nagesh Ragavendra; Steve Raman; Elizabeth Seja; Darlene Rosario; Sabrina Miles; David C. Diamond; Zhiyong Qiu; Mihail Obrocea; Adrian Bot
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies
Glen J. Weiss; Jeffrey R. Infante; E. Gabriela Chiorean; Mitesh J. Borad; Johanna C. Bendell; Julian R. Molina; Raoul Tibes; Ramesh K. Ramanathan; Karen Lewandowski; Suzanne F. Jones; Mario E. Lacouture; Virginia K. Langmuir; Hank Lee; Stew Kroll; Howard A. Burris, III
Predictive Biomarkers and Personalized Medicine
Overexpression of miR-200c Induces Chemoresistance in Esophageal Cancers Mediated Through Activation of the Akt Signaling Pathway
Rie Hamano; Hiroshi Miyata; Makoto Yamasaki; Yukinori Kurokawa; Johji Hara; Jeong ho Moon; Kiyokazu Nakajima; Shuji Takiguchi; Yoshiyuki Fujiwara; Masaki Mori; Yuichiro Doki
Pretreatment Transcriptional Profiling for Predicting Response to Neoadjuvant Chemoradiotherapy in Rectal Adenocarcinoma
Kate H. Brettingham-Moore; Cuong P. Duong; Danielle M. Greenawalt; Alexander G. Heriot; Jason Ellul; Christopher A. Dow; William K. Murray; Rodney J. Hicks; Joe Tjandra; Michael Chao; Andrew Bui; Daryl Lim Joon; Robert J. S. Thomas; Wayne A. Phillips
Letters to the Editor
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