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15 March 2011
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In mice bearing orthotopic SKOV3ip1 human ovarian tumors, the diaphragms contained lymphatic vessels of increased density and branching and lymphatic valve structures disappeared completely. Lymphatic valves were visualized by using anti-CD31 (green) and LYVE-1 (blue) double staining in whole mounts of the diaphragm. For further details, please see Liao and coworkers on page 1415 in this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Molecular Pathways
CCR Focus
Human Cancer Biology
Involvement of the TGF-β and β-Catenin Pathways in Pelvic Lymph Node Metastasis in Early-Stage Cervical Cancer
Maartje G. Noordhuis; Rudolf S.N. Fehrmann; G. Bea A. Wisman; Esther R. Nijhuis; Jelmer J. van Zanden; Perry D. Moerland; Emiel Ver Loren van Themaat; Haukeline H. Volders; Mirjam Kok; Klaske A. ten Hoor; Harry Hollema; Elisabeth G.E. de Vries; Geertruida H. de Bock; Ate G.J. van der Zee; Ed Schuuring
Cancer Therapy: Preclinical
Reduced Dose and Intermittent Treatment with Lapatinib and Trastuzumab for Potent Blockade of the HER Pathway in HER2/neu-Overexpressing Breast Tumor Xenografts
Mothaffar F. Rimawi; Lisa S. Wiechmann; Yen-Chao Wang; Catherine Huang; Ilenia Migliaccio; Meng-Fen Wu; Carolina Gutierrez; Susan G. Hilsenbeck; Grazia Arpino; Suleiman Massarweh; Robin Ward; Robert Soliz; C. Kent Osborne; Rachel Schiff
Antitumor Activity of BIBF 1120, a Triple Angiokinase Inhibitor, and Use of VEGFR2+pTyr+ Peripheral Blood Leukocytes as a Pharmacodynamic Biomarker In Vivo
Kanae Kudo; Tokuzo Arao; Kaoru Tanaka; Tomoyuki Nagai; Kazuyuki Furuta; Kazuko Sakai; Hiroyasu Kaneda; Kazuko Matsumoto; Daisuke Tamura; Keiichi Aomatsu; Marco A. De Velasco; Yoshihiko Fujita; Nagahiro Saijo; Masatoshi Kudo; Kazuto Nishio
SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis
Joseph P. Ritchie; Vishnu C. Ramani; Yongsheng Ren; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Sergio Penco; Claudio Pisano; Paolo Carminati; Monica Tortoreto; Franco Zunino; Israel Vlodavsky; Ralph D. Sanderson; Yang Yang
Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo
Peramaiyan Rajendran; Tina H. Ong; Luxi Chen; Feng Li; Muthu K. Shanmugam; Shireen Vali; Taher Abbasi; Shweta Kapoor; Ashish Sharma; Alan Prem Kumar; Kam M. Hui; Gautam Sethi
Imaging, Diagnosis, Prognosis
A20, ABIN-1/2, and CARD11 Mutations and Their Prognostic Value in Gastrointestinal Diffuse Large B-Cell Lymphoma
Gehong Dong; Estelle Chanudet; Naiyan Zeng; Alex Appert; Yun-Wen Chen; Wing-Yan Au; Rifat A. Hamoudi; A. James Watkins; Hongtao Ye; Hongxiang Liu; Zifen Gao; Shih-Sung Chuang; Gopesh Srivastava; Ming-Qing Du
Genomic and Clinical Analysis of Amplification of the 13q31 Chromosomal Region in Alveolar Rhabdomyosarcoma: A Report from the Children's Oncology Group
Jennifer L. Reichek; Fenghai Duan; Lynette M. Smith; Donna M. Gustafson; Roddy S. O'Connor; Chune Zhang; Mandy J. Dunlevy; Julie M. Gastier-Foster; Frederic G. Barr
Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell Carcinomas
David S.P. Tan; Marjan Iravani; W. Glenn McCluggage; Maryou B.K. Lambros; Fernanda Milanezi; Alan Mackay; Charles Gourley; Felipe C. Geyer; Radost Vatcheva; Joanne Millar; Karen Thomas; Rachael Natrajan; Kay Savage; Kerry Fenwick; Alistair Williams; Charles Jameson; Mona El-Bahrawy; Martin E. Gore; Hani Gabra; Stanley B. Kaye; Alan Ashworth; Jorge S. Reis-Filho
Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer
Joo Mi Yi; Mashaal Dhir; Leander Van Neste; Stephanie R. Downing; Jana Jeschke; Sabine C. Glöckner; Marilia de Freitas Calmon; Craig M. Hooker; Juan M. Funes; Chris Boshoff; Kim M. Smits; Manon van Engeland; Matty P. Weijenberg; Christine A. Iacobuzio-Donahue; James G. Herman; Kornel E. Schuebel; Stephen B. Baylin; Nita Ahuja
Cancer Therapy: Clinical
A Phase I Study of the Heat Shock Protein 90 Inhibitor Alvespimycin (17-DMAG) Given Intravenously to Patients with Advanced Solid Tumors
Simon Pacey; Richard H. Wilson; Mike Walton; Martin M. Eatock; Anthea Hardcastle; Anna Zetterlund; Hendrik-Tobias Arkenau; Javier Moreno-Farre; Udai Banerji; Belle Roels; Heidi Peachey; Wynne Aherne; Johan S. de Bono; Florence Raynaud; Paul Workman; Ian Judson
Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas
Anastasios Stathis; Sebastien J. Hotte; Eric X. Chen; Holger W. Hirte; Amit M. Oza; Patricia Moretto; Sheila Webster; Anne Laughlin; Lee-Anne Stayner; Shauna McGill; Lisa Wang; Wen-jiang Zhang; Igor Espinoza-Delgado; Julianne L. Holleran; Merrill J. Egorin; Lillian L. Siu
Predictive Biomarkers and Personalized Medicine
Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer
Gottfried E. Konecny; Boris Winterhoff; Teodora Kolarova; Jingwei Qi; Kanthinh Manivong; Judy Dering; Guorong Yang; Meenal Chalukya; He-Jing Wang; Lee Anderson; Kimberly R. Kalli; Richard S. Finn; Charles Ginther; Siân Jones; Victor E. Velculescu; Darren Riehle; William A. Cliby; Sophia Randolph; Maria Koehler; Lynn C. Hartmann; Dennis J. Slamon
Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
Geoffrey R. Oxnard; Maria E. Arcila; Camelia S. Sima; Gregory J. Riely; Juliann Chmielecki; Mark G. Kris; William Pao; Marc Ladanyi; Vincent A. Miller
Failure of Downregulation of Survivin Following Neoadjuvant Radiochemotherapy in Rectal Cancer Is Associated with Distant Metastases and Shortened Survival
Thilo Sprenger; Franz Rödel; Tim Beissbarth; Lena-Christin Conradi; Hilka Rothe; Kia Homayounfar; Hendrik A. Wolff; B. Michael Ghadimi; Müjdat Yildirim; Heinz Becker; Claus Rödel; Torsten Liersch
ERCC1 and ERCC2 Polymorphisms Predict Clinical Outcomes of Oxaliplatin-Based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis
Ming Yin; Jingrong Yan; Eva Martinez-Balibrea; Francesco Graziano; Heinz-Josef Lenz; Hyo-Jin Kim; Jacques Robert; Seock-Ah Im; Wei-Shu Wang; Marie-Christine Etienne-Grimaldi; Qingyi Wei
Corrections
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