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15 August 2010
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Codetection of microRNA and protein markers in formalin-fixed paraffin-embedded clinical specimens. Cover image depicts expression of microRNAs and proteins in normal prostate tissue. Diffuse and apical cytoplasmic staining of cytokeratins 8 and 18 (red) as well as membranous staining of E-cadherin (blue) highlights prostatic epithelium. Cytoplasmic-enriched staining of miR-141 (green) is confined to epithelial cells, whereas that of let-7a (orange) is detected in both epithelial and stromal compartments. For further details, please see the article by Sempere and colleagues on page 4246 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
Editorial
CCR Translations
Molecular Pathways
Reviews
Human Cancer Biology
NF1 Inactivation in Adult Acute Myelogenous Leukemia
Brian Parkin; Peter Ouillette; Yin Wang; Yan Liu; Whitney Wright; Diane Roulston; Anjali Purkayastha; Amanda Dressel; Judith Karp; Paula Bockenstedt; Ammar Al-Zoubi; Moshe Talpaz; Lisa Kujawski; Yang Liu; Kerby Shedden; Sajid Shakhan; Cheng Li; Harry Erba; Sami N. Malek
Mutation of SDHB is a Cause of Hypoxia-Related High-Altitude Paraganglioma
Nidia Y. Cerecer-Gil; Luis E. Figuera; Francisco J. Llamas; Mauricio Lara; José G. Escamilla; Ruben Ramos; Gerardo Estrada; A. Karim Hussain; José Gaal; Esther Korpershoek; Ronald R. de Krijger; Winand N.M. Dinjens; Peter Devilee; Jean Pierre Bayley
Genomic Profiling Reveals Alternative Genetic Pathways of Meningioma Malignant Progression Dependent on the Underlying NF2 Status
Stéphane Goutagny; Hong Wei Yang; Jessica Zucman-Rossi; Jennifer Chan; Jonathan M. Dreyfuss; Peter J. Park; Peter M. Black; Marco Giovannini; Rona S. Carroll; Michel Kalamarides
Cancer Therapy: Preclinical
Gene Array and Fluorescence In situ Hybridization Biomarkers of Activity of Saracatinib (AZD0530), a Src Inhibitor, in a Preclinical Model of Colorectal Cancer
John J. Arcaroli; Basel M. Touban; Aik Choon Tan; Marileila Varella-Garcia; Rebecca W. Powell; S. Gail Eckhardt; Paul Elvin; Dexiang Gao; Wells A. Messersmith
Inhibition of Hypoxia Inducible Factor-1α by Dihydroxyphenylethanol, a Product from Olive Oil, Blocks Microsomal Prostaglandin-E Synthase-1/Vascular Endothelial Growth Factor Expression and Reduces Tumor Angiogenesis
Erika Terzuoli; Sandra Donnini; Antonio Giachetti; Miguel A. Iñiguez; Manuel Fresno; Giovanni Melillo; Marina Ziche
Imaging, Diagnosis, Prognosis
Quantitation of p95HER2 in Paraffin Sections by Using a p95-Specific Antibody and Correlation with Outcome in a Cohort of Trastuzumab-Treated Breast Cancer Patients
Jeff Sperinde; Xueguang Jin; Jayee Banerjee; Elicia Penuel; Anasuya Saha; Gundo Diedrich; Weidong Huang; Kim Leitzel; Jodi Weidler; Suhail M. Ali; Eva-Maria Fuchs; Christian F. Singer; Wolfgang J. Köstler; Michael Bates; Gordon Parry; John Winslow; Allan Lipton
Fluorescence-Based Codetection with Protein Markers Reveals Distinct Cellular Compartments for Altered MicroRNA Expression in Solid Tumors
Lorenzo F. Sempere; Meir Preis; Todd Yezefski; Haoxu Ouyang; Arief A. Suriawinata; Asli Silahtaroglu; Jose R. Conejo-Garcia; Sakari Kauppinen; Wendy Wells; Murray Korc
Genomic Alterations and Allelic Imbalances Are Strong Prognostic Predictors in Osteosarcoma
Jan Smida; Daniel Baumhoer; Michael Rosemann; Axel Walch; Stefan Bielack; Christopher Poremba; Klaus Remberger; Eberhard Korsching; Wolfram Scheurlen; Christian Dierkes; Stefan Burdach; Gernot Jundt; Michael J. Atkinson; Michaela Nathrath
MiRNA-196 Is Upregulated in Glioblastoma But Not in Anaplastic Astrocytoma and Has Prognostic Significance
Yanlei Guan; Masahiro Mizoguchi; Koji Yoshimoto; Nobuhiro Hata; Tadahisa Shono; Satoshi O. Suzuki; Yukie Araki; Daisuke Kuga; Akira Nakamizo; Toshiyuki Amano; Xinlong Ma; Kenshi Hayashi; Tomio Sasaki
Corrections
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