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15 April 2009
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Overexpression and constitutive nuclear localization of cohesin protease Separase in human cancers. Immunofluorescence localization of Separase (red) to nucleus in a breast ductal carcinoma sample [nuclei are stained with DAPI (blue)] is shown here. Strong positive correlation of Separase mRNA expression with tumor grade and a strong negative correlation with disease-free and overall survival were also noted in breast and prostate carcinomas. For further details, please see Meyer and co-workers on page 2703 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
CCR Translations
Molecular Pathways
Perspective
Review
Human Cancer Biology
RhoGDI2 Expression Is Associated with Tumor Growth and Malignant Progression of Gastric Cancer
Hee Jun Cho; Kyoung Eun Baek; Sun-Mi Park; In-Kyu Kim; Yeong-Lim Choi; Hye-Jung Cho; In-Koo Nam; Eun Mi Hwang; Jae-Yong Park; Jae Yoon Han; Sang Soo Kang; Dong Chul Kim; Won Sup Lee; Mi-Ni Lee; Goo Taeg Oh; Jae Won Kim; Chang Won Lee; Jiyun Yoo
Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals RGS17 as a Likely Candidate Gene
Ming You; Daolong Wang; Pengyuan Liu; Haris Vikis; Michael James; Yan Lu; Yian Wang; Min Wang; Qiong Chen; Dongmei Jia; Yan Liu; Weidong Wen; Ping Yang; Zhifu Sun; Susan M. Pinney; Wei Zheng; Xiao-Ou Shu; Jirong Long; Yu-Tang Gao; Yong-Bing Xiang; Wong-Ho Chow; Nat Rothman; Gloria M. Petersen; Mariza de Andrade; Yanhong Wu; Julie M. Cunningham; Jonathan S. Wiest; Pamela R. Fain; Ann G. Schwartz; Luc Girard; Adi Gazdar; Colette Gaba; Henry Rothschild; Diptasri Mandal; Teresa Coons; Juwon Lee; Elena Kupert; Daniela Seminara; John Minna; Joan E. Bailey-Wilson; Christopher I. Amos; Marshall W. Anderson
Genomic Profiling of Chondrosarcoma: Chromosomal Patterns in Central and Peripheral Tumors
Karolin H. Hallor; Johan Staaf; Judith V.M.G. Bovée; Pancras C.W. Hogendoorn; Anne-Marie Cleton-Jansen; Sakari Knuutila; Suvi Savola; Tarja Niini; Otte Brosjö; Henrik C.F. Bauer; Fredrik Vult von Steyern; Kjell Jonsson; Mikael Skorpil; Nils Mandahl; Fredrik Mertens
Surgical Stress Promotes Tumor Growth in Ovarian Carcinoma
Jeong-Won Lee; Mian M.K. Shahzad; Yvonne G. Lin; Guillermo Armaiz-Pena; Lingegowda S. Mangala; Hee-Dong Han; Hye-Sun Kim; Eun Ji Nam; Nicholas B. Jennings; Jyotsnabaran Halder; Alpa M. Nick; Rebecca L. Stone; Chunhua Lu; Susan K. Lutgendorf; Steve W. Cole; Anna E. Lokshin; Anil K. Sood
Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers
Rachael Natrajan; Maryou B. Lambros; Socorro María Rodríguez-Pinilla; Gema Moreno-Bueno; David S.P. Tan; Caterina Marchió; Radost Vatcheva; Sydonia Rayter; Betania Mahler-Araujo; Laura G. Fulford; Daniela Hungermann; Alan Mackay; Anita Grigoriadis; Kerry Fenwick; Narinder Tamber; David Hardisson; Andrew Tutt; Jose Palacios; Christopher J. Lord; Horst Buerger; Alan Ashworth; Jorge S. Reis-Filho
Cancer Therapy: Preclinical
β-Catenin Small Interfering RNA Successfully Suppressed Progression of Multiple Myeloma in a Mouse Model
Eishi Ashihara; Eri Kawata; Yoko Nakagawa; Chihiro Shimazaski; Junya Kuroda; Kyoko Taniguchi; Hitoji Uchiyama; Ruriko Tanaka; Asumi Yokota; Miki Takeuchi; Yuri Kamitsuji; Tohru Inaba; Masafumi Taniwaki; Shinya Kimura; Taira Maekawa
CD20-Directed Small Modular Immunopharmaceutical, TRU-015, Depletes Normal and Malignant B Cells
Martha S. Hayden-Ledbetter; Chuck G. Cerveny; Erik Espling; William A. Brady; Laura S. Grosmaire; Philip Tan; Robert Bader; Sonya Slater; Christy A. Nilsson; Dauphine S. Barone; Alexander Simon; Cheryl Bradley; Peter A. Thompson; Alan F. Wahl; Jeffrey A. Ledbetter
Efficacy of Systemically Administered Oncolytic Vaccinia Virotherapy for Malignant Gliomas Is Enhanced by Combination Therapy with Rapamycin or Cyclophosphamide
Xue Qing Lun; Ji-Hyun Jang; Nan Tang; Helen Deng; Renee Head; John C. Bell; David F. Stojdl; Catherine L. Nutt; Donna L. Senger; Peter A. Forsyth; J. Andrea McCart
Induction of Wilms' Tumor Protein (WT1)–Specific Antitumor Immunity Using a Truncated WT1-Expressing Adenovirus Vaccine
Takuya Osada; Christopher Y. Woo; Matthew McKinney; Xiao Yi Yang; Gangjun Lei; Heather G. LaBreche; Zachary C. Hartman; Donna Niedzwiecki; Nelson Chao; Andrea Amalfitano; Michael A. Morse; H. Kim Lyerly; Timothy M. Clay
Gene Expression Patterns in Mismatch Repair-Deficient Colorectal Cancers Highlight the Potential Therapeutic Role of Inhibitors of the Phosphatidylinositol 3-Kinase-AKT-Mammalian Target of Rapamycin Pathway
Eduardo Vilar; Bhramar Mukherjee; Rork Kuick; Leon Raskin; David E. Misek; Jeremy M.G. Taylor; Thomas J. Giordano; Samir M. Hanash; Eric R. Fearon; Gad Rennert; Stephen B. Gruber
Imaging, Diagnosis, Prognosis
FDG-PET/CT Imaging Predicts Histopathologic Treatment Responses after the Initial Cycle of Neoadjuvant Chemotherapy in High-Grade Soft-Tissue Sarcomas
Matthias R. Benz; Johannes Czernin; Martin S. Allen-Auerbach; William D. Tap; Sarah M. Dry; David Elashoff; Kira Chow; Vladimir Evilevitch; Jeff J. Eckardt; Michael E. Phelps; Wolfgang A. Weber; Fritz C. Eilber
Synuclein-γ Is Closely Involved in Perineural Invasion and Distant Metastasis in Mouse Models and Is a Novel Prognostic Factor in Pancreatic Cancer
Taizo Hibi; Taisuke Mori; Mariko Fukuma; Ken Yamazaki; Akinori Hashiguchi; Taketo Yamada; Minoru Tanabe; Koichi Aiura; Takao Kawakami; Atsushi Ogiwara; Tomoo Kosuge; Masaki Kitajima; Yuko Kitagawa; Michiie Sakamoto
Molecular Detection of Lymph Node Metastases in Breast Cancer Patients: Results of a Multicenter Trial Using the One-Step Nucleic Acid Amplification Assay
Yasuhiro Tamaki; Futoshi Akiyama; Takuji Iwase; Tomoyo Kaneko; Hitoshi Tsuda; Kazuhiko Sato; Shigeto Ueda; Masayuki Mano; Norikazu Masuda; Masashi Takeda; Masahiko Tsujimoto; Katsuhide Yoshidome; Hideo Inaji; Hiromu Nakajima; Yoshifumi Komoike; Tatsuki R. Kataoka; Seigo Nakamura; Koyu Suzuki; Koichiro Tsugawa; Kenichi Wakasa; Tsuyoshi Okino; Yo Kato; Shinzaburo Noguchi; Nariaki Matsuura
Cancer Therapy: Clinical
The Impact of HER2/neu Expression Level on Response to the E75 Vaccine: From U.S. Military Cancer Institute Clinical Trials Group Study I-01 and I-02
Linda C. Benavides; Jeremy D. Gates; Mark G. Carmichael; Ritesh Patel; Jarrod P. Holmes; Matthew T. Hueman; Elizabeth A. Mittendorf; Dianna Craig; Alexander Stojadinovic; Sathibalan Ponniah; George E. Peoples
Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma
Raphaël Maréchal; John R. Mackey; Raymond Lai; Pieter Demetter; Marc Peeters; Marc Polus; Carol E. Cass; James Young; Isabelle Salmon; Jacques Devière; Jean-Luc Van Laethem
Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment
Carla M.M. Prado; Vickie E. Baracos; Linda J. McCargar; Tony Reiman; Marina Mourtzakis; Katia Tonkin; John R. Mackey; Sheryl Koski; Edith Pituskin; Michael B. Sawyer
Phase II Trial of Tipifarnib plus Neoadjuvant Doxorubicin-Cyclophosphamide in Patients with Clinical Stage IIB-IIIC Breast Cancer
Joseph A. Sparano; Stacy Moulder; Aslamuzzaman Kazi; Domenico Coppola; Abdissa Negassa; Linda Vahdat; Tianhong Li; Christine Pellegrino; Susan Fineberg; Pam Munster; Mokenge Malafa; David Lee; Shira Hoschander; Una Hopkins; Dawn Hershman; John J. Wright; Celina Kleer; Sofia Merajver; Said M. Sebti
Correction
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