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1 June 2009
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Expression of DNA methyltransferase-3B (DNMT3B) in human colon cancer. Among 765 colorectal cancers, DNMT3B expression was associated with CpG island methylator phenotype (CIMP)-high, suggesting that DNMT3B contributes to CIMP-high in colorectal cancer. For further details, please see the article by Nosho and colleagues on page 3663 of this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
CCR Translations
Molecular Pathways
Human Cancer Biology
Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast Cancer
Roshan Agarwal; Ana-Maria Gonzalez-Angulo; Simen Myhre; Mark Carey; Ju-Seog Lee; Jens Overgaard; Jan Alsner; Katherine Stemke-Hale; Ana Lluch; Richard M. Neve; Wen Lin Kuo; Therese Sorlie; Aysegul Sahin; Vicente Valero; Khandan Keyomarsi; Joe W. Gray; Anne-Lise Borresen-Dale; Gordon B. Mills; Bryan T. Hennessy
DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer
Katsuhiko Nosho; Kaori Shima; Natsumi Irahara; Shoko Kure; Yoshifumi Baba; Gregory J. Kirkner; Li Chen; Sumita Gokhale; Aditi Hazra; Donna Spiegelman; Edward L. Giovannucci; Rudolf Jaenisch; Charles S. Fuchs; Shuji Ogino
Cancer Therapy: Preclinical
Molecular Mechanisms Underlying Effects of Epidermal Growth Factor Receptor Inhibition on Invasion, Proliferation, and Angiogenesis in Experimental Glioma
Jean-Sébastien Guillamo; Sophie de Boüard; Samuel Valable; Lena Marteau; Pascal Leuraud; Yannick Marie; Marie-France Poupon; Jean-Jacques Parienti; Eric Raymond; Marc Peschanski
Histone Deacetylase Inhibitors Induce a Very Broad, Pleiotropic Anticancer Drug Resistance Phenotype in Acute Myeloid Leukemia Cells by Modulation of Multiple ABC Transporter Genes
Stefanie Hauswald; Jesus Duque-Afonso; Michaela M. Wagner; Florian M. Schertl; Michael Lübbert; Christian Peschel; Ulrich Keller; Thomas Licht
HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer
Lynn M. Knowles; Laura P. Stabile; Ann Marie Egloff; Mary E. Rothstein; Sufi M. Thomas; Christopher T. Gubish; Edwina C. Lerner; Raja R. Seethala; Shinsuke Suzuki; Kelly M. Quesnelle; Sarah Morgan; Robert L. Ferris; Jennifer R. Grandis; Jill M. Siegfried
Therapeutic Targeting of ATP7B in Ovarian Carcinoma
Lingegowda S. Mangala; Vesna Zuzel; Rosemarie Schmandt; Erik S. Leshane; Jyotsna B. Halder; Guillermo N. Armaiz-Pena; Whitney A. Spannuth; Takemi Tanaka; Mian M.K. Shahzad; Yvonne G. Lin; Alpa M. Nick; Christopher G. Danes; Jeong-Won Lee; Nicholas B. Jennings; Pablo E. Vivas-Mejia; Judith K. Wolf; Robert L. Coleman; Zahid H. Siddik; Gabriel Lopez-Berestein; Svetlana Lutsenko; Anil K. Sood
Imaging, Diagnosis, Prognosis
Imaging a Genetically Engineered Oncolytic Vaccinia Virus (GLV-1h99) Using a Human Norepinephrine Transporter Reporter Gene
Peter Brader; Kaitlyn J. Kelly; Nanhai Chen; Yong A. Yu; Qian Zhang; Pat Zanzonico; Eva M. Burnazi; Rashid E. Ghani; Inna Serganova; Hedvig Hricak; Aladar A. Szalay; Yuman Fong; Ronald G. Blasberg
Serum Peptidome Profiling Revealed Platelet Factor 4 as a Potential Discriminating Peptide Associated with Pancreatic Cancer
Georg Martin Fiedler; Alexander Benedikt Leichtle; Julia Kase; Sven Baumann; Uta Ceglarek; Klaus Felix; Tim Conrad; Helmut Witzigmann; Arved Weimann; Christof Schütte; Johann Hauss; Markus Büchler; Joachim Thiery
Proteasome Enzymatic Activities in Plasma as Risk Stratification of Patients with Acute Myeloid Leukemia and Advanced-Stage Myelodysplastic Syndrome
Wanlong Ma; Hagop Kantarjian; Benjamin Bekele; Amber C. Donahue; Xi Zhang; Zhong J. Zhang; Susan O'Brien; Elihu Estey; Zeev Estrov; Jorge Cortes; Michael Keating; Francis Giles; Maher Albitar
Tumoral Expression of TXR1 and TSP1 Predicts Overall Survival of Patients with Lung Adenocarcinoma Treated with First-line Docetaxel-Gemcitabine Regimen
Chara Papadaki; Dimitris Mavroudis; Maria Trypaki; Anastasios Koutsopoulos; Efstathios Stathopoulos; Dora Hatzidaki; Eleftheria Tsakalaki; Vassilis Georgoulias; John Souglakos
Cancer Therapy: Clinical
Quality of Reporting of Serious Adverse Drug Events to an Institutional Review Board: A Case Study with the Novel Cancer Agent, Imatinib Mesylate
David A. Dorr; Rachel Burdon; Dennis P. West; Jennifer Lagman; Christina Georgopoulos; Steven M. Belknap; June M. McKoy; Benjamin Djulbegovic; Beatrice J. Edwards; Sigmund A. Weitzman; Simone Boyle; Martin S. Tallman; Moshe Talpaz; Oliver Sartor; Charles L. Bennett
Multi-center, Placebo-controlled, Double-blind, Randomized Study of Oral Toceranib Phosphate (SU11654), a Receptor Tyrosine Kinase Inhibitor, for the Treatment of Dogs with Recurrent (Either Local or Distant) Mast Cell Tumor Following Surgical Excision
Cheryl A. London; Phyllis B. Malpas; Stacey L. Wood-Follis; Joseph F. Boucher; Anthony W. Rusk; Mona P. Rosenberg; Carolyn J. Henry; Kathy L. Mitchener; Mary K. Klein; John G. Hintermeister; Philip J. Bergman; Guillermo C. Couto; Guy N. Mauldin; Gina M. Michels
Phase I Study of YM155, a Novel Survivin Suppressant, in Patients with Advanced Solid Tumors
Taroh Satoh; Isamu Okamoto; Masaki Miyazaki; Ryotaroh Morinaga; Asuka Tsuya; Yoshikazu Hasegawa; Masaaki Terashima; Shinya Ueda; Masahiro Fukuoka; Yutaka Ariyoshi; Toshikazu Saito; Noriyuki Masuda; Hirokazu Watanabe; Tetsuo Taguchi; Toru Kakihara; Yumiko Aoyama; Yohko Hashimoto; Kazuhiko Nakagawa
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