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1 March 2008
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H&E staining of a muscle-invasive KU-7 bladder tumor one month after orthotopic tumor cell inoculation in an untreated nude mouse demonstrating multifocal and aggressive disease. Magnification ×10 on a BLISS microscope imaging workstation. In contrast, bi-weekly intravesical chemotherapy with HTI-286 would have significantly delayed tumor growth.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
In Memoriam
Editorial
CCR Drug Update
Molecular Pathways
Report from the FDA
U.S. Food and Drug Administration Approval: Panitumumab for Epidermal Growth Factor Receptor–Expressing Metastatic Colorectal Carcinoma with Progression Following Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Containing Chemotherapy Regimens
Ruthann M. Giusti; Kaushikkumar Shastri; Anne M. Pilaro; Chana Fuchs; Ruth Cordoba-Rodriguez; Kallappa Koti; Mark Rothmann; Angela Yuxin Men; Hong Zhao; Monica Hughes; Patricia Keegan; Karen D. Weiss; Richard Pazdur
Reviews
Immunohistochemical Analysis of Phosphotyrosine Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor Autocrine Signaling Pathways in Head and Neck Cancers and Metastatic Lymph Nodes
Raja R. Seethala; William E. Gooding; Phoebe N. Handler; Bobby Collins; Qing Zhang; Jill M. Siegfried; Jennifer R. Grandis
Human Cancer Biology
Targeted Intraoperative Radiotherapy Impairs the Stimulation of Breast Cancer Cell Proliferation and Invasion Caused by Surgical Wounding
Barbara Belletti; Jayant S. Vaidya; Sara D'Andrea; Frank Entschladen; Mario Roncadin; Francesca Lovat; Stefania Berton; Tiziana Perin; Ezio Candiani; Sonia Reccanello; Andrea Veronesi; Vincenzo Canzonieri; Mauro G. Trovò; Kurt S. Zaenker; Alfonso Colombatti; Gustavo Baldassarre; Samuele Massarut
Imaging, Diagnosis, Prognosis
Vascular Imaging of Solid Tumors in Rats with a Radioactive Arsenic-Labeled Antibody that Binds Exposed Phosphatidylserine
Marc Jennewein; Matthew A. Lewis; Dawen Zhao; Edward Tsyganov; Nikolai Slavine; Jin He; Linda Watkins; Vikram D. Kodibagkar; Sean O'Kelly; Padmakar Kulkarni; Peter P. Antich; Alex Hermanne; Frank Rösch; Ralph P. Mason; Philip E. Thorpe
WDR19 Expression is Increased in Prostate Cancer Compared with Normal Cells, but Low-Intensity Expression in Cancers is Associated with Shorter Time to Biochemical Failures and Local Recurrence
Biaoyang Lin; Angelita G. Utleg; Karsten Gravdal; James T. White; Ole J. Halvorsen; Wei Lu; Lawrence D. True; Robert Vessella; Paul H. Lange; Peter S. Nelson; Leroy Hood; Karl-Henning Kalland; Lars A. Akslen
Sensitive and Specific New Enzyme-Linked Immunosorbent Assay for N-ERC/Mesothelin Increases its Potential as a Useful Serum Tumor Marker for Mesothelioma
Kazu Shiomi; Yoshiaki Hagiwara; Kouji Sonoue; Tatsuya Segawa; Kazuya Miyashita; Masahiro Maeda; Hiroshi Izumi; Kimihiko Masuda; Masataka Hirabayashi; Takao Moroboshi; Takashi Yoshiyama; Atsuko Ishida; Yuji Natori; Akira Inoue; Masashi Kobayashi; Yukinori Sakao; Hideaki Miyamoto; Kazuhisa Takahashi; Okio Hino
Cancer Therapy: Clinical
Phase I and Pharmacokinetic Study of Bortezomib in Combination with Idarubicin and Cytarabine in Patients with Acute Myelogenous Leukemia
Eyal C. Attar; Daniel J. DeAngelo; Jeffrey G. Supko; Ferdinando D'Amato; David Zahrieh; Andres Sirulnik; Martha Wadleigh; Karen K. Ballen; Steve McAfee; Kenneth B. Miller; James Levine; Ilene Galinsky; Elizabeth G. Trehu; David Schenkein; Donna Neuberg; Richard M. Stone; Philip C. Amrein
Allogeneic Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation
Dan Laheru; Eric Lutz; James Burke; Barbara Biedrzycki; Sara Solt; Beth Onners; Irena Tartakovsky; John Nemunaitis; Dung Le; Elizabeth Sugar; Kristen Hege; Elizabeth Jaffee
Phase I/II Study of Atrasentan, an Endothelin A Receptor Antagonist, in Combination with Paclitaxel and Carboplatin as First-Line Therapy in Advanced Non–Small Cell Lung Cancer
Alberto A. Chiappori; Eric Haura; Francisco A. Rodriguez; David Boulware; Rachna Kapoor; Anthony M. Neuger; Richard Lush; Barbara Padilla; Michelle Burton; Charles Williams; George Simon; Scott Antonia; Daniel M. Sullivan; Gerold Bepler
Cancer Therapy: Preclinical
Sensitivity to Epidermal Growth Factor Receptor Inhibitor Requires E-Cadherin Expression in Urothelial Carcinoma Cells
Peter C. Black; Gordon A. Brown; Teruo Inamoto; Marissa Shrader; Ameeta Arora; Arlene O. Siefker-Radtke; Liana Adam; Dan Theodorescu; Xifeng Wu; Mark F. Munsell; Menashe Bar-Eli; David J. McConkey; Colin P.N. Dinney
Acquirement of Rituximab Resistance in Lymphoma Cell Lines Is Associated with Both Global CD20 Gene and Protein Down-Regulation Regulated at the Pretranscriptional and Posttranscriptional Levels
Myron S. Czuczman; Scott Olejniczak; Aruna Gowda; Adam Kotowski; Arvinder Binder; Harman Kaur; Joy Knight; Petr Starostik; Julie Deans; Francisco J. Hernandez-Ilizaliturri
Cancer Prevention and Susceptibility
Correction
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