Issues

Human D52 or D53 expression is associated with reduced cell area and actin stress fibers in 3T3 cells. A stably transfected cell line expressing D53 is shown labeled with FITC-phalloidin (green), and DAPI as a nuclear counterstain (blue). Cells with high D53 expression were small, with poor actin stress fibers, whereas cells with undetectable to low D53 expression were larger, with prominent actin stress fibers (original magnification, x400). For further details, please see Shehata and colleagues on page 5050 in this issue.