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15 May 2008
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Cover Image
Cover Image
Apoptotic cancer cells (bright red) identified by TUNEL staining in orthotopic MDA-MB-435 xenograft tumors. Female nude mice with xenograft tumors were treated with vehicle (upper left panel), TRAIL (upper right panel), aspirin (lower left panel), or the combination of aspirin and TRAIL (lower right panel). Aspirin cooperated with TRAIL to induce apoptosis and reduce tumor burden in this model, supporting the potential therapeutic utility of this combination. For further details, please see Lu and colleagues on page 3168 in this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Molecular Pathways
Review
Human Cancer Biology
Helicobacter pylori Augments Growth of Gastric Cancers via the Lipopolysaccharide-Toll-like Receptor 4 Pathway whereas Its Lipopolysaccharide Attenuates Antitumor Activities of Human Mononuclear Cells
Kentaro Chochi; Takashi Ichikura; Manabu Kinoshita; Takashi Majima; Nariyoshi Shinomiya; Hironori Tsujimoto; Toshinobu Kawabata; Hidekazu Sugasawa; Satoshi Ono; Shuhji Seki; Hidetaka Mochizuki
Epigenetic Silencing of the Tetraspanin CD9 during Disease Progression in Multiple Myeloma Cells and Correlation with Survival
Elke De Bruyne; Tomas Jan Bos; Kewal Asosingh; Isabelle Vande Broek; Eline Menu; Els Van Valckenborgh; Peter Atadja; Valérie Coiteux; Xavier Leleu; Kris Thielemans; Ben Van Camp; Karin Vanderkerken; Ivan Van Riet
Detection of Copy Number Alterations in Metastatic Melanoma by a DNA Fluorescence In situ Hybridization Probe Panel and Array Comparative Genomic Hybridization: A Southwest Oncology Group Study (S9431)
Stephen R. Moore; Diane L. Persons; Jeffrey A. Sosman; Dolores Bobadilla; Victoria Bedell; David D. Smith; Sandra R. Wolman; Ralph J. Tuthill; Jim Moon; Vernon K. Sondak; Marilyn L. Slovak
Gene Expression Profiles Associated with the Presence of a Fibrotic Focus and the Growth Pattern in Lymph Node–Negative Breast Cancer
Gert G. Van den Eynden; Marcel Smid; Steven J. Van Laere; Cecile G. Colpaert; Ilse Van der Auwera; Trinh Xuan Bich; Peter van Dam; Michael A. den Bakker; Luc Y. Dirix; Eric A. Van Marck; Peter B. Vermeulen; John A. Foekens
Loss of Heterozygosity at the BRCA2 Locus Detected by Multiplex Ligation-Dependent Probe Amplification is Common in Prostate Cancers from Men with a Germline BRCA2 Mutation
Amber J. Willems; Sarah-Jane Dawson; Hema Samaratunga; Alessandro De Luca; Yoland C. Antill; John L. Hopper; Heather J. Thorne; and kConFab Investigators
Imaging, Diagnosis, Prognosis
Imaging Bone and Soft Tissue Tumors with the Proliferation Marker [18F]Fluorodeoxythymidine
Andreas K. Buck; Ken Herrmann; Christian Meyer zum Büschenfelde; Malik E. Juweid; Mark Bischoff; Gerhard Glatting; Gregor Weirich; Peter Möller; Hans-Jürgen Wester; Klemens Scheidhauer; Tobias Dechow; Christian Peschel; Markus Schwaiger; Sven N. Reske
Novel Glioblastoma Markers with Diagnostic and Prognostic Value Identified through Transcriptome Analysis
Sreekanth P. Reddy; Ramona Britto; Katyayni Vinnakota; Hebbar Aparna; Hari Kishore Sreepathi; Balaram Thota; Arpana Kumari; B.M. Shilpa; M. Vrinda; Srikantha Umesh; Cini Samuel; Mitesh Shetty; Ashwani Tandon; Paritosh Pandey; Sridevi Hegde; A.S. Hegde; Anandh Balasubramaniam; B.A. Chandramouli; Vani Santosh; Paturu Kondaiah; Kumaravel Somasundaram; M.R. Satyanarayana Rao
Translocations Involving the Immunoglobulin Heavy Chain Gene Locus Predict Better Survival in Gastric Diffuse Large B-Cell Lymphoma
Shotaro Nakamura; Hongtao Ye; Chris M. Bacon; Alison Goatly; Hongxiang Liu; Lucy Kerr; Alison H. Banham; Berthold Streubel; Takashi Yao; Masazumi Tsuneyoshi; Antonella Savio; Morishige Takeshita; Peggy Dartigues; Agnès Ruskoné-Fourmestraux; Takayuki Matsumoto; Mitsuo Iida; Ming-Qing Du
Bcl-B Expression in Human Epithelial and Nonepithelial Malignancies
Maryla Krajewska; Shinichi Kitada; Jane N. Winter; Daina Variakojis; Alan Lichtenstein; Dayong Zhai; Michael Cuddy; Xianshu Huang; Frederic Luciano; Cheryl H. Baker; Hoguen Kim; Eunah Shin; Susan Kennedy; Allen H. Olson; Andrzej Badzio; Jacek Jassem; Ivo Meinhold-Heerlein; Michael J. Duffy; Aaron D. Schimmer; Ming Tsao; Ewan Brown; Anne Sawyers; Michael Andreeff; Dan Mercola; Stan Krajewski; John C. Reed
Impact of Insulin-Like Growth Factor Type 1 Receptor, Epidermal Growth Factor Receptor, and HER2 Expressions on Outcomes of Patients with Gastric Cancer
Junichi Matsubara; Yasuhide Yamada; Yoshinori Hirashima; Daisuke Takahari; Natsuko T. Okita; Ken Kato; Tetsuya Hamaguchi; Kuniaki Shirao; Yasuhiro Shimada; Tadakazu Shimoda
N-[N-[(S)-1,3-Dicarboxypropyl]Carbamoyl]-4-[18F]Fluorobenzyl-l-Cysteine, [18F]DCFBC: A New Imaging Probe for Prostate Cancer
Ronnie C. Mease; Crystal L. Dusich; Catherine A. Foss; Hayden T. Ravert; Robert F. Dannals; Jurgen Seidel; Andrew Prideaux; James J. Fox; George Sgouros; Alan P. Kozikowski; Martin G. Pomper
Cancer Therapy: Clinical
Pilot Study of Vaccination with Recombinant CEA-MUC-1-TRICOM Poxviral-Based Vaccines in Patients with Metastatic Carcinoma
James L. Gulley; Philip M. Arlen; Kwong-Yok Tsang; Junko Yokokawa; Claudia Palena; Diane J. Poole; Cinzia Remondo; Vittore Cereda; Jacquin L. Jones; Mary P. Pazdur; Jack P. Higgins; James W. Hodge; Seth M. Steinberg; Herbert Kotz; William L. Dahut; Jeffrey Schlom
Phase II Trial of Tipifarnib as Maintenance Therapy in First Complete Remission in Adults with Acute Myelogenous Leukemia and Poor-Risk Features
Judith E. Karp; B. Douglas Smith; Ivana Gojo; Jeffrey E. Lancet; Jacqueline Greer; Maureen Klein; Larry Morris; Mark J. Levis; Steven D. Gore; John J. Wright; Elizabeth Garrett-Mayer
Postoperative Adjuvant Dendritic Cell–Based Immunotherapy in Patients with Relapsed Glioblastoma Multiforme
Steven De Vleeschouwer; Steffen Fieuws; Stefan Rutkowski; Frank Van Calenbergh; Johannes Van Loon; Jan Goffin; Raf Sciot; Guido Wilms; Philippe Demaerel; Monika Warmuth-Metz; Niels Soerensen; Johannes E.A. Wolff; Sabine Wagner; Eckhart Kaempgen; Stefaan W. Van Gool
Phase I Clinical and Pharmacokinetic Study of Plitidepsin as a 1-Hour Weekly Intravenous Infusion in Patients with Advanced Solid Tumors
Miguel A. Izquierdo; Angela Bowman; Margarita García; Duncan Jodrell; Marisa Martinez; Beatriz Pardo; Javier Gómez; José A. López-Martin; José Jimeno; José R. Germá; John F. Smyth
Cancer Therapy: Preclinical
Inhibition of Vascular Endothelial Growth Factor-A Signaling Induces Hypertension: Examining the Effect of Cediranib (Recentin; AZD2171) Treatment on Blood Pressure in Rat and the Use of Concomitant Antihypertensive Therapy
Jon O. Curwen; Helen L. Musgrove; Jane Kendrew; Graham H.P. Richmond; Donald J. Ogilvie; Stephen R. Wedge
Cancer Prevention and Susceptibility
VDR and SRD5A2 Polymorphisms Combine to Increase Risk for Prostate Cancer in Both Non–Hispanic White and Hispanic White Men
Kathleen C. Torkko; Adrie van Bokhoven; Phoung Mai; Joke Beuten; Ivana Balic; Tim E. Byers; John E. Hokanson; Jill M. Norris; Anna E. Barón; M. Scott Lucia; Ian M. Thompson; Robin J. Leach
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