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15 November 2006
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Cover Image
FISH analysis of 9p21 locus in HPV16-positive oropharyngeal squamous cell carcinoma. The cytogenetic analysis was performed using a CEP9/9p21 probe to interphasic nuclei. The nuclei showed a normal disomic hybridization pattern of 9p21 represented by two centromere 9 signals (green spots) coupled with two 9p21 signals (red spots). For further details, please see Perrone et al. on page 6643 in this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Editorial
The Biology Behind
Molecular Pathways
Review
Human Cancer Biology
Mapping Geographic Zones of Cancer Risk with Epigenetic Biomarkers in Normal Breast Tissue
Pearlly S. Yan; Chinnambally Venkataramu; Ashraf Ibrahim; Joseph C. Liu; Rulong Z. Shen; Nils M. Diaz; Barbara Centeno; Frank Weber; Yu-Wei Leu; Charles L. Shapiro; Charis Eng; Timothy J. Yeatman; Tim H.-M. Huang
Molecular and Cytogenetic Subgroups of Oropharyngeal Squamous Cell Carcinoma
Federica Perrone; Simona Suardi; Elisa Pastore; Paola Casieri; Marta Orsenigo; Stefano Caramuta; Gianpaolo Dagrada; Marco Losa; Lisa Licitra; Paolo Bossi; Samantha Staurengo; Maria Oggionni; Laura Locati; Giulio Cantu; Massimo Squadrelli; Antonino Carbone; Marco A. Pierotti; Silvana Pilotti
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas
Jorge Sergio Reis-Filho; Pete T. Simpson; Nicholas C. Turner; Maryou Ballo Lambros; Chris Jones; Alan Mackay; Anita Grigoriadis; David Sarrio; Kay Savage; Tim Dexter; Marjan Iravani; Kerry Fenwick; Barbara Weber; David Hardisson; Fernando Carlos Schmitt; Jose Palacios; Sunil R. Lakhani; Alan Ashworth
Imaging, Diagnosis, Prognosis
Vascular Targeted Nanoparticles for Imaging and Treatment of Brain Tumors
G. Ramachandra Reddy; Mahaveer S. Bhojani; Patrick McConville; Jonathan Moody; Bradford A. Moffat; Daniel E. Hall; Gwangseong Kim; Yong-Eun L. Koo; Michael J. Woolliscroft; James V. Sugai; Timothy D. Johnson; Martin A. Philbert; Raoul Kopelman; Alnawaz Rehemtulla; Brian D. Ross
Axillary Lymph Node Nanometastases Are Prognostic Factors for Disease-Free Survival and Metastatic Relapse in Breast Cancer Patients
Patrizia Querzoli; Massimo Pedriali; Rosa Rinaldi; Anna Rita Lombardi; Elia Biganzoli; Patrizia Boracchi; Stefano Ferretti; Claudia Frasson; Caterina Zanella; Sara Ghisellini; Federico Ambrogi; Laura Antolini; Mauro Piantelli; Stefano Iacobelli; Ettore Marubini; Saverio Alberti; Italo Nenci
Loss of Breast Cancer Metastasis Suppressor 1 Protein Expression Predicts Reduced Disease-Free Survival in Subsets of Breast Cancer Patients
David G. Hicks; Brian J. Yoder; Sarah Short; Shannon Tarr; Nichole Prescott; Joseph P. Crowe; Andrea E. Dawson; G. Thomas Budd; Steven Sizemore; Muzaffer Cicek; Toni K. Choueiri; Raymond R. Tubbs; Daniel Gaile; Norma Nowak; Mary Ann Accavitti-Loper; Andra R. Frost; Danny R. Welch; Graham Casey
Galectin-3 Expression Is Associated with Tumor Progression and Pattern of Sun Exposure in Melanoma
Victor G. Prieto; Alexandra A. Mourad-Zeidan; Vladislava Melnikova; Marcella M. Johnson; Adriana Lopez; A. Hafeez Diwan; Alexander J.F. Lazar; Steven S. Shen; Peter S. Zhang; Jon A. Reed; Jeffrey E. Gershenwald; Avraham Raz; Menashe Bar-Eli
Cancer Therapy: Clinical
A Phase I Study of OncoVEXGM-CSF, a Second-Generation Oncolytic Herpes Simplex Virus Expressing Granulocyte Macrophage Colony-Stimulating Factor
Jennifer C.C. Hu; Robert S. Coffin; Ceri J. Davis; Nicola J. Graham; Natasha Groves; Peter J. Guest; Kevin J. Harrington; Nicholas D. James; Colin A. Love; Iain McNeish; Louise C. Medley; Agnieszka Michael; Christopher M. Nutting; Hardev S. Pandha; Claire A. Shorrock; Julie Simpson; Jan Steiner; Neil M. Steven; Dennis Wright; R. Charles Coombes
Nitroglycerin Treatment May Enhance Chemosensitivity to Docetaxel and Carboplatin in Patients with Lung Adenocarcinoma
Hiroyasu Yasuda; Katsutoshi Nakayama; Mika Watanabe; Satoshi Suzuki; Hiromi Fuji; Shoji Okinaga; Akio Kanda; Kiyoshi Zayasu; Takahiko Sasaki; Masanori Asada; Tomoko Suzuki; Motoki Yoshida; Shinsuke Yamanda; Daisuke Inoue; Tomohiro Kaneta; Takashi Kondo; Yoshihiro Takai; Hidetada Sasaki; Kazuhiro Yanagihara; Mutsuo Yamaya
Cancer Therapy: Preclinical
Dominant-Negative Fibroblast Growth Factor Receptor Expression Enhances Antitumoral Potency of Oncolytic Herpes Simplex Virus in Neural Tumors
Ta-Chiang Liu; Tingguo Zhang; Hiroshi Fukuhara; Toshihiko Kuroda; Tomoki Todo; Xavier Canron; Andreas Bikfalvi; Robert L. Martuza; Andreas Kurtz; Samuel D. Rabkin
A Tracer Dose of Technetium-99m–Labeled Liposomes Can Estimate the Effect of Hyperthermia on Intratumoral Doxil Extravasation
Miriam M. Kleiter; Daohai Yu; Lenore A. Mohammadian; Nelsen Niehaus; Ivan Spasojevic; Linda Sanders; Benjamin L. Viglianti; Pavel S. Yarmolenko; Marlene Hauck; Neil A. Petry; Terence Z. Wong; Mark W. Dewhirst; Donald E. Thrall
Vascular Endothelial Growth Factor Blockade Reduces Intratumoral Regulatory T Cells and Enhances the Efficacy of a GM-CSF–Secreting Cancer Immunotherapy
Betty Li; Alshad S. Lalani; Thomas C. Harding; Bo Luan; Kathryn Koprivnikar; Guang Huan Tu; Rodney Prell; Melinda J. VanRoey; Andrew D. Simmons; Karin Jooss
Arsenic Trioxide Affects Signal Transducer and Activator of Transcription Proteins through Alteration of Protein Tyrosine Kinase Phosphorylation
Meir Wetzler; Michael T. Brady; Erin Tracy; Zhang-Rong Li; Kathleen A. Donohue; Kieran L. O'Loughlin; Yijun Cheng; Amir Mortazavi; Amy A. McDonald; Padmaja Kunapuli; Paul K. Wallace; Maria R. Baer; John K. Cowell; Heinz Baumann
Combination Mammalian Target of Rapamycin Inhibitor Rapamycin and HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin Has Synergistic Activity in Multiple Myeloma
Lanie K. Francis; Yazan Alsayed; Xavier Leleu; Xiaoying Jia; Ujjal K. Singha; Judith Anderson; Michael Timm; Hai Ngo; Ganwei Lu; Alissa Huston; Lori A. Ehrlich; Elizabeth Dimmock; Suzanne Lentzsch; Teru Hideshima; G. David Roodman; Kenneth C. Anderson; Irene M. Ghobrial
A Novel HSV-1 Virus, JS1/34.5−/47−, Purges Contaminating Breast Cancer Cells From Bone Marrow
Jennifer C. Hu; Matthew J. Booth; Gopichand Tripuraneni; Derek Davies; Syed A.A. Zaidi; Manuela Tamburo de Bella; Martin J. Slade; Stephen B. Marley; Myrtle Y.A. Gordon; Robert S. Coffin; R. Charles Coombes; Tahereh Kamalati
Letters to the Editor
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