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Volume 12, Issue 16
15 August 2006
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    Cover Image

    issue cover
    Mice bearing orthotopic ovarian carcinoma were treated with FAK siRNA in DOPC liposomes with or without docetaxel. The cover figure shows immunofluorescence dual-localization (yellow) of endothelial cells (red) and apoptotic cells (green) in sections obtained from mice treated with combination therapy. The greatest increase in endothelial cell apoptosis was observed following treatment with combination of FAK siRNA-DOPC and docetaxel. For further details, see Halder et al. on page 4916 in this issue.
  • PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265

The Biology Behind

CpG Island Methylator Phenotype and Childhood Leukemia
Norman J. Lacayo; Jorge F. DiMartino; Michael C. Wei; Gary V. Dahl
View articletitled, CpG Island Methylator Phenotype and Childhood Leukemia
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Molecular Pathways

Estrogen Receptor Pathway: Resistance to Endocrine Therapy and New Therapeutic Approaches
Beverly Moy; Paul E. Goss
View articletitled, Estrogen Receptor Pathway: Resistance to Endocrine Therapy and New Therapeutic Approaches
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Review

Improving Antitumor Immune Responses by Circumventing Immunoregulatory Cells and Mechanisms
Gregory Lizée; Laszlo G. Radvanyi; Willem W. Overwijk; Patrick Hwu
View articletitled, Improving Antitumor Immune Responses by Circumventing Immunoregulatory Cells and Mechanisms
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Human Cancer Biology

Characterization and Expression of CT45 in Hodgkin's Lymphoma
Hans-Jürgen Heidebrecht; Alexander Claviez; Marie Luise Kruse; Marc Pollmann; Friedrich Buck; Sönke Harder; Markus Tiemann; Wolfgang Dörffel; Reza Parwaresch
View articletitled, Characterization and Expression of CT45 in Hodgkin's Lymphoma
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Th1 Response and Cytotoxicity Genes Are Down-Regulated in Cutaneous T-Cell Lymphoma
Sonja Hahtola; Soile Tuomela; Laura Elo; Tiina Häkkinen; Leena Karenko; Boguslaw Nedoszytko; Hannele Heikkilä; Ulpu Saarialho-Kere; Jadwiga Roszkiewicz; Tero Aittokallio; Riitta Lahesmaa; Annamari Ranki
View articletitled, Th1 Response and Cytotoxicity Genes Are Down-Regulated in Cutaneous T-Cell Lymphoma
Supplementary data
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Natural Killer Receptors on CD8 T Cells and Natural Killer Cells from Different HLA-C Phenotypes in Melanoma Patients
José A. Campillo; Jorge A. Martínez-Escribano; M. Rosa Moya-Quiles; Luis A. Marín; Manuel Muro; Natalia Guerra; Antonio Parrado; Matilde Campos; José F. Frías; Alfredo Minguela; Ana M. García-Alonso; María Rocío Álvarez-López
View articletitled, Natural Killer Receptors on CD8 T Cells and Natural Killer Cells from Different HLA-C Phenotypes in Melanoma Patients
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CHEK2-Positive Breast Cancers in Young Polish Women
Cezary Cybulski; Bohdan Górski; Tomasz Huzarski; Tomasz Byrski; Jacek Gronwald; Tadeusz Dębniak; Dominika Wokołorczyk; Anna Jakubowska; Elżbieta Kowalska; Oleg Oszurek; Steven A. Narod; Jan Lubiński
View articletitled, <em>CHEK2</em>-Positive Breast Cancers in Young Polish Women
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Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer
Nilay S. Patel; Michael S. Dobbie; Mark Rochester; Graham Steers; Richard Poulsom; Karena Le Monnier; David W. Cranston; Ji-Liang Li; Adrian L. Harris
View articletitled, Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer
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Imaging, Diagnosis, Prognosis

CpG Island Methylator Phenotype Redefines the Prognostic Effect of t(12;21) in Childhood Acute Lymphoblastic Leukemia
Jose Roman-Gomez; Antonio Jimenez-Velasco; Xabier Agirre; Juan A. Castillejo; German Navarro; Maria J. Calasanz; Leire Garate; Edurne San Jose-Eneriz; Lucia Cordeu; Felipe Prosper; Anabel Heiniger; Antonio Torres
View articletitled, CpG Island Methylator Phenotype Redefines the Prognostic Effect of t(12;21) in Childhood Acute Lymphoblastic Leukemia
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Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma
Xiao-Song Wang; Zheng Zhang; Hong-Cheng Wang; Jian-Liang Cai; Qing-Wen Xu; Meng-Qiang Li; Yi-Cheng Chen; Xiao-Ping Qian; Tian-Jing Lu; Li-Zhang Yu; Yu Zhang; Dian-Qi Xin; Yan-Qun Na; Wei-Feng Chen
View articletitled, Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma
Supplementary data
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Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases
Niven Mehra; Maarten Penning; Jolanda Maas; Laurens V. Beerepoot; Nancy van Daal; Carla H. van Gils; Rachel H. Giles; Emile E. Voest
View articletitled, Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases
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MDM2 Promoter SNP309 Is Associated with the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C
Narayan Dharel; Naoya Kato; Ryosuke Muroyama; Masaru Moriyama; Run-Xuan Shao; Takao Kawabe; Masao Omata
View articletitled, MDM2 Promoter SNP309 Is Associated with the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C
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Preoperative Serum Caveolin-1 as a Prognostic Marker for Recurrence in a Radical Prostatectomy Cohort
Salahaldin A. Tahir; Anna Frolov; Teresa G. Hayes; Martha P. Mims; Brian J. Miles; Seth P. Lerner; Thomas M. Wheeler; Gustavo Ayala; Timothy C. Thompson; Dov Kadmon
View articletitled, Preoperative Serum Caveolin-1 as a Prognostic Marker for Recurrence in a Radical Prostatectomy Cohort
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Presence of Phosphorylated Hepatocyte Growth Factor Receptor/c-Met Is Associated with Tumor Progression and Survival in Patients with Conventional Renal Cell Carcinoma
Yasuyoshi Miyata; Hiroshi Kanetake; Shigeru Kanda
View articletitled, Presence of Phosphorylated Hepatocyte Growth Factor Receptor/c-Met Is Associated with Tumor Progression and Survival in Patients with Conventional Renal Cell Carcinoma
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Cancer Therapy: Clinical

A Phase 1 Study of ABT-751, an Orally Bioavailable Tubulin Inhibitor, Administered Daily for 7 Days Every 21 Days in Pediatric Patients with Solid Tumors
Elizabeth Fox; John M. Maris; Brigitte C. Widemann; Kysa Meek; Anne Goodwin; Wendy Goodspeed; Marie Kromplewski; Molly E. Fouts; Diane Medina; Steve Y. Cho; Susan L. Cohn; Andrew Krivoshik; Anne E. Hagey; Peter C. Adamson; Frank M. Balis
View articletitled, A Phase 1 Study of ABT-751, an Orally Bioavailable Tubulin Inhibitor, Administered Daily for 7 Days Every 21 Days in Pediatric Patients with Solid Tumors
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Real-time Dose Adjustment of Cyclophosphamide in a Preparative Regimen for Hematopoietic Cell Transplant: A Bayesian Pharmacokinetic Approach
David H. Salinger; Jeannine S. McCune; Aaron G. Ren; Danny D. Shen; John T. Slattery; Brian Phillips; George B. McDonald; Paolo Vicini
View articletitled, Real-time Dose Adjustment of Cyclophosphamide in a Preparative Regimen for Hematopoietic Cell Transplant: A Bayesian Pharmacokinetic Approach
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Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08
Patrick Y. Wen; W.K. Alfred Yung; Kathleen R. Lamborn; Patricia L. Dahia; Yanfeng Wang; Bin Peng; Lauren E. Abrey; Jeffrey Raizer; Timothy F. Cloughesy; Karen Fink; Mark Gilbert; Susan Chang; Larry Junck; David Schiff; Frank Lieberman; Howard A. Fine; Minesh Mehta; H. Ian Robins; Lisa M. DeAngelis; Morris D. Groves; Vinay K. Puduvalli; Victor Levin; Charles Conrad; Elizabeth A. Maher; Kenneth Aldape; Michael Hayes; Laurie Letvak; Merrill J. Egorin; Renaud Capdeville; Richard Kaplan; Anthony J. Murgo; Charles Stiles; Michael D. Prados
View articletitled, Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08
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Cancer Therapy: Preclinical

CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice
Xiaohua Xin; Tinya J. Abrams; Paul W. Hollenbach; Katherine G. Rendahl; Yan Tang; Yoko A. Oei; Millicent G. Embry; Debbie E. Swinarski; Evelyn N. Garrett; Nancy K. Pryer; Suzanne Trudel; Bahija Jallal; Dirk B. Mendel; Carla C. Heise
View articletitled, CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice
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Focal Adhesion Kinase Targeting Using In vivo Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy
Jyotsnabaran Halder; Aparna A. Kamat; Charles N. Landen, Jr.; Liz Y. Han; Susan K. Lutgendorf; Yvonne G. Lin; William M. Merritt; Nicholas B. Jennings; Arturo Chavez-Reyes; Robert L. Coleman; David M. Gershenson; Rosemarie Schmandt; Steven W. Cole; Gabriel Lopez-Berestein; Anil K. Sood
View articletitled, Focal Adhesion Kinase Targeting Using <em>In vivo</em> Short Interfering RNA Delivery in Neutral Liposomes for Ovarian Carcinoma Therapy
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Antitumor Effect of Trastuzumab for Pancreatic Cancer with High HER-2 Expression and Enhancement of Effect by Combined Therapy with Gemcitabine
Kenjiro Kimura; Tetsuji Sawada; Midori Komatsu; Masafumi Inoue; Kazuya Muguruma; Tamahiro Nishihara; Yoshito Yamashita; Nobuya Yamada; Masaichi Ohira; Kosei Hirakawa
View articletitled, Antitumor Effect of Trastuzumab for Pancreatic Cancer with High HER-2 Expression and Enhancement of Effect by Combined Therapy with Gemcitabine
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Delivery of Telomerase Reverse Transcriptase Small Interfering RNA in Complex with Positively Charged Single-Walled Carbon Nanotubes Suppresses Tumor Growth
Zhuohan Zhang; Xiaoying Yang; Yuan Zhang; Bin Zeng; Shujing Wang; Tianhui Zhu; Richard B.S. Roden; Yongsheng Chen; Rongcun Yang
View articletitled, Delivery of Telomerase Reverse Transcriptase Small Interfering RNA in Complex with Positively Charged Single-Walled Carbon Nanotubes Suppresses Tumor Growth
Supplementary data
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Bcl-2 Protein in 518A2 Melanoma Cells In vivo and In vitro
Luba Benimetskaya; Kanyalakshmi Ayyanar; Noah Kornblum; Daniela Castanotto; John Rossi; Sijian Wu; Johnathan Lai; Bob D. Brown; Natalia Popova; Paul Miller; Harilyn McMicken; Yin Chen; C.A. Stein
View articletitled, Bcl-2 Protein in 518A2 Melanoma Cells <em>In vivo</em> and <em>In vitro</em>
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Peptidome from Renal Cell Carcinoma Contains Antigens Recognized by CD4+ T Cells and Shared among Tumors of Different Histology
Elena Tassi; Valeria Facchinetti; Samantha Seresini; Anna Borri; Giacomo Dell'Antonio; Claudio Garavaglia; Giulia Casorati; Maria Pia Protti
View articletitled, Peptidome from Renal Cell Carcinoma Contains Antigens Recognized by CD4<sup>+</sup> T Cells and Shared among Tumors of Different Histology
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Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue
Guozheng Liu; Shuping Dou; George Mardirossian; Jiang He; Surong Zhang; Xinrong Liu; Mary Rusckowski; Donald J. Hnatowich
View articletitled, Successful Radiotherapy of Tumor in Pretargeted Mice by <sup>188</sup>Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue
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In vitro and In vivo Evidence of Metallopanstimulin-1 in Gastric Cancer Progression and Tumorigenicity
Yun-wei Wang; Ying Qu; Jian-fang Li; Xue-hua Chen; Bing-ya Liu; Qin-long Gu; Zheng-gang Zhu
View articletitled, <em>In vitro</em> and <em>In vivo</em> Evidence of Metallopanstimulin-1 in Gastric Cancer Progression and Tumorigenicity
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Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1
Jose C. Juarez; Oscar Betancourt, Jr.; Steven R. Pirie-Shepherd; Xiaojun Guan; Melissa L. Price; David E. Shaw; Andrew P. Mazar; Fernando Doñate
View articletitled, Copper Binding by Tetrathiomolybdate Attenuates Angiogenesis and Tumor Cell Proliferation through the Inhibition of Superoxide Dismutase 1
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Tumor-Directed Radiation and the Immunotoxin SS1P in the Treatment of Mesothelin-Expressing Tumor Xenografts
Raffit Hassan; Juanita Williams-Gould; Seth M. Steinberg; David J. Liewehr; Junko Yokokawa; Kwong Y. Tsang; Robert J. Surawski; Tamalee Scott; Kevin Camphausen
View articletitled, Tumor-Directed Radiation and the Immunotoxin SS1P in the Treatment of Mesothelin-Expressing Tumor Xenografts
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Radiosensitivity Enhancement by Combined Treatment of Celecoxib and Gefitinib on Human Lung Cancer Cells
Ji Sun Park; Hyun Jung Jun; Moon Jun Cho; Kwan Ho Cho; Jin Soo Lee; Jae Ill Zo; Hongryull Pyo
View articletitled, Radiosensitivity Enhancement by Combined Treatment of Celecoxib and Gefitinib on Human Lung Cancer Cells
Supplementary data
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Letters to the Editor

Cancer Chemotherapy and Cognitive Function in Rodent Models: Memory Impairment Induced by Cyclophosphamide in Mice
André B. Reiriz; Gustavo K. Reolon; Thales Preissler; Joemerson O. Rosado; João Antônio P. Henriques; Rafael Roesler; Gilberto Schwartsmann
View articletitled, Cancer Chemotherapy and Cognitive Function in Rodent Models: Memory Impairment Induced by Cyclophosphamide in Mice
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Corrections

Article on Reduced Plasma RNA Integrity
View articletitled, Article on Reduced Plasma RNA Integrity
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Article on BCL-2 as a Prognostic Marker
View articletitled, Article on BCL-2 as a Prognostic Marker
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  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

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