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15 July 2006
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Oxaliplatin-resistant colorectal cancer cells exhibit morphologic and molecular changes consistent with epithelial-to-mesenchymal transition. Immunofluorescent staining for E-cadherin (red, right panels) and β-catenin (green, left panels) on HT29 parental (upper panels) and oxaliplatin-resistant (lower panels) cells demonstrated changes in localization of E-cadherin and β-catenin from their usual cell membrane-associated site to the cytoplasm and nucleus, respectively. For further details, please see Yang et al. on page 4147. in this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Editorial
The Biology Behind
CCR Drug Updates
Molecular Pathways
Review
Human Cancer Biology
Unexpected Abundance of HLA Class II Presented Peptides in Primary Renal Cell Carcinomas
Jörn Dengjel; Maria-Dorothea Nastke; Cécile Gouttefangeas; Gitsios Gitsioudis; Oliver Schoor; Florian Altenberend; Margret Müller; Björn Krämer; Anna Missiou; Martina Sauter; Jörg Hennenlotter; Dorothee Wernet; Arnulf Stenzl; Hans-Georg Rammensee; Karin Klingel; Stefan Stevanović
Isolation of Human Prostatic Epithelial Plasma Membranes for Proteomics Using Mirror Image Tissue Banking of Radical Prostatectomy Specimens
Kanishka Sircar; Louis Gaboury; Lydia Ouadi; Melanie Mecteau; Eleonora Scarlata; Fred Saad; Armen Aprikian; Simon Tanguay; Steven Lapointe; Christian Lussier; Tina Miletti; Joel Lanoix
Imaging, Diagnosis, Prognosis
Circulating Tumor Cells at Each Follow-up Time Point during Therapy of Metastatic Breast Cancer Patients Predict Progression-Free and Overall Survival
Daniel F. Hayes; Massimo Cristofanilli; G. Thomas Budd; Matthew J. Ellis; Alison Stopeck; M. Craig Miller; Jeri Matera; W. Jeffrey Allard; Gerald V. Doyle; Leon W.W.M. Terstappen
High Fluorodeoxyglucose Uptake on Positron Emission Tomography in Patients with Advanced Non–Small Cell Lung Cancer on Platinum-Based Combination Chemotherapy
Kyung-Hun Lee; Se-Hoon Lee; Dong-Wan Kim; Won Jun Kang; June-Key Chung; Seock-Ah Im; Tae-You Kim; Young Whan Kim; Yung-Jue Bang; Dae Seog Heo
Inverse Effects of Mucin on Survival of Matched Hereditary Nonpolyposis Colorectal Cancer and Sporadic Colorectal Cancer Patients
Jeng-Fu You; Ling-Ling Hsieh; Chung Rong Changchien; Jinn-Shiun Chen; Jim-Ray Chen; Jy-Ming Chiang; Chien Yuh Yeh; Pao-Shiu Hsieh; Chung-Wei Fan; Chun-Ting Liu; Reiping Tang
Cancer Therapy: Clinical
Clinical and Biological Effects of Recombinant Human Interleukin-18 Administered by Intravenous Infusion to Patients with Advanced Cancer
Michael J. Robertson; James W. Mier; Theodore Logan; Michael Atkins; Henry Koon; Kevin M. Koch; Steven Kathman; Lini N. Pandite; Coreen Oei; Lyndon C. Kirby; Roxanne C. Jewell; William N. Bell; Linda M. Thurmond; Jill Weisenbach; Suzanne Roberts; Mohammed M. Dar
A Phase I Clinical and Pharmacokinetic Study of Oral CI-1033 in Combination with Docetaxel in Patients with Advanced Solid Tumors
Linda L. Garland; Manuel Hidalgo; David S. Mendelson; David P. Ryan; Banu K. Arun; Jennifer L. Lovalvo; Irene A. Eiseman; Stephen C. Olson; Peter F. Lenehan; Joseph P. Eder
Epidermal Growth Factor Receptor Kinase Domain Mutations in Esophageal and Pancreatic Adenocarcinomas
Eunice L. Kwak; Janusz Jankowski; Sarah P. Thayer; Gregory Y. Lauwers; Brian W. Brannigan; Patricia L. Harris; Ross A. Okimoto; Sara M. Haserlat; David R. Driscoll; David Ferry; Beth Muir; Jeff Settleman; Charles S. Fuchs; Matthew H. Kulke; David P. Ryan; Jeff W. Clark; Dennis C. Sgroi; Daniel A. Haber; Daphne W. Bell
Cancer Therapy: Preclinical
Systemic Anti-CD25 Monoclonal Antibody Administration Safely Enhances Immunity in Murine Glioma without Eliminating Regulatory T Cells
Peter E. Fecci; Alison E. Sweeney; Peter M. Grossi; Smita K. Nair; Christopher A. Learn; Duane A. Mitchell; Xiuyu Cui; Thomas J. Cummings; Darell D. Bigner; Eli Gilboa; John H. Sampson
Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo
Rongrong Ge; Vaishali Rajeev; Partha Ray; Edmund Lattime; Susan Rittling; Satya Medicherla; Andy Protter; Alison Murphy; Jit Chakravarty; Sundeep Dugar; George Schreiner; Nicola Barnard; Michael Reiss
Overcoming Drug-Resistant Cancer by a Newly Developed Copper Chelate through Host-Protective Cytokine-Mediated Apoptosis
Ananda Mookerjee; Jayati Mookerjee Basu; Pranabananda Dutta; Surajit Majumder; Sankar Bhattacharyya; Jaydip Biswas; Smarajit Pal; Pratima Mukherjee; Sanghamitra Raha; Rathindra N. Baral; Tania Das; Thomas Efferth; Gourisankar Sa; Shyamal Roy; Soumitra K. Choudhuri
Correction
Novel Agents in the Treatment of Lung Cancer: Advances in EGFR-Targeted Agents
Summary Statement: Novel Agents in the Treatment of Lung Cancer: Advances in Epidermal Growth Factor Receptor-Targeted Agents
Thomas J. Lynch; Alex A. Adjei; Paul A. Bunn, Jr.; Tim G. Eisen; Jeffrey Engelman; Glenwood D. Goss; Daniel A. Haber; John V. Heymach; Pasi A. Jänne; Bruce E. Johnson; David H. Johnson; Rogerio C. Lilenbaum; Matthew Meyerson; Alan B. Sandler; Lecia V. Sequist; Jeffrey Settleman; Kwok-Kin Wong; Carol S. Hart
Epidermal Growth Factor Receptor Mutation Testing in the Care of Lung Cancer Patients
Lecia V. Sequist; Victoria A. Joshi; Pasi A. Jänne; Daphne W. Bell; Panos Fidias; Neal I. Lindeman; David N. Louis; Jeffrey C. Lee; Eugene J. Mark; Janina Longtine; Peter Verlander; Raju Kucherlapati; Matthew Meyerson; Daniel A. Haber; Bruce E. Johnson; Thomas J. Lynch
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