Issues
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Cover Image
Cover Image
About the Cover
The αvβ3 integrin is a key player in angiogenesis and tumor metastasis. The cover image shows an immunohistochemical stain of αvβ3 expression on the endothelium of a microvessel in a pigmented villonodular synovitis. In the same lesion, αvβ3 expression could also be demonstrated noninvasively by positron emission tomography (PET) using the αvβ3 selective tracer [18F]Galacto-RGD. The authors demonstrate that [18F]Galacto-RGD PET successfully identifies the level of αvβ3 expression in man noninvasively. For further details, please see Beer et al. on page 3942. - PDF Icon PDF LinkTable of Contents
Editorials
The Biology Behind
Molecular Pathways
Review
Human Cancer Biology
Accurate Prediction of BRCA1 and BRCA2 Heterozygous Genotype Using Expression Profiling after Induced DNA Damage
Imaging, Diagnosis, Prognosis
Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib
Prognostic Associations of Activated Mitogen-Activated Protein Kinase and Akt Pathways in Glioblastoma
Positron Emission Tomography Using [18F]Galacto-RGD Identifies the Level of Integrin αvβ3 Expression in Man
Molecular Profiling of Laser-Microdissected Matched Tumor and Normal Breast Tissue Identifies Karyopherin α2 as a Potential Novel Prognostic Marker in Breast Cancer
Cancer Therapy: Clinical
Phase II Study of Pomegranate Juice for Men with Rising Prostate-Specific Antigen following Surgery or Radiation for Prostate Cancer
Cancer Therapy: Preclinical
Establishment in Severe Combined Immunodeficiency Mice of Subrenal Capsule Xenografts and Transplantable Tumor Lines from a Variety of Primary Human Lung Cancers: Potential Models for Studying Tumor Progression–Related Changes
PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity
Signaling via ErbB2 and ErbB3 Associates with Resistance and Epidermal Growth Factor Receptor (EGFR) Amplification with Sensitivity to EGFR Inhibitor Gefitinib in Head and Neck Squamous Cell Carcinoma Cells
Blockage of Epidermal Growth Factor Receptor-Phosphatidylinositol 3-Kinase-AKT Signaling Increases Radiosensitivity of K-RAS Mutated Human Tumor Cells In vitro by Affecting DNA Repair
Letters to the Editor
Correction
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