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Transabdominal perfusion PET scan after infusion of oxygen-15 radiolabeled water showing a well perfused spleen and normal liver with poorly perfused hepatic metastases (anteriorly and laterally). Blood flow modelling confirmed that perfusion to metastases improved after administration of carbogen and nicotinamide. For further details, please see Gupta et al. on page 3115 in this issue. - PDF Icon PDF LinkTable of Contents
The Biology Behind
Report from the FDA
CCR Drug Updates
Molecular Pathways
Human Cancer Biology
Mixed Lineage Leukemia–Rearranged Childhood Pro-B and CD10-Negative Pre-B Acute Lymphoblastic Leukemia Constitute a Distinct Clinical Entity
CpG Island M`ethylation Status in Gastric Carcinoma with and without Infection of Epstein-Barr Virus
17β-Estradiol Induces Down-Regulation of Cap43/NDRG1/Drg-1, a Putative Differentiation-Related and Metastasis Suppressor Gene, in Human Breast Cancer Cells
Phosphatidylinositol 3′-Kinase/AKT Signaling Is Activated in Medulloblastoma Cell Proliferation and Is Associated with Reduced Expression of PTEN
Imaging, Diagnosis, Prognosis
Achieving a Major Molecular Response at the Time of a Complete Cytogenetic Response (CCgR) Predicts a Better Duration of CCgR in Imatinib-Treated Chronic Myeloid Leukemia Patients
NOTCH1 Mutations in T-Cell Acute Lymphoblastic Leukemia: Prognostic Significance and Implication in Multifactorial Leukemogenesis
Cancer Therapy: Clinical
Epidermal Growth Factor Receptor Messenger RNA Expression, Gene Dosage, and Gefitinib Sensitivity in Non–Small Cell Lung Cancer
Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia
Carbogen and Nicotinamide Increase Blood Flow and 5-Fluorouracil Delivery but not 5-Fluorouracil Retention in Colorectal Cancer Metastases in Patients
Cancer Therapy: Preclinical
Detection and Functional Analysis of CD8+ T Cells Specific for PRAME: a Target for T-Cell Therapy
Infectivity-Enhanced Adenoviruses Deliver Efficacy in Clinical Samples and Orthotopic Models of Disseminated Gastric Cancer
Immunogenic HLA-B*0702-Restricted Epitopes Derived from Human Telomerase Reverse Transcriptase That Elicit Antitumor Cytotoxic T-Cell Responses
Cancer Prevention
Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome
Correction
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