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Human Cancer Biology
Ferritin Contributes to Melanoma Progression by Modulating Cell Growth and Sensitivity to Oxidative Stress
Alfonso Baldi; Daniela Lombardi; Patrizia Russo; Emanuele Palescandolo; Antonio De Luca; Daniele Santini; Feliciano Baldi; Luigi Rossiello; Maria Lucia Dell'Anna; Arianna Mastrofrancesco; Vittoria Maresca; Enrica Flori; Pier Giorgio Natali; Mauro Picardo; Marco G. Paggi
Imaging, Diagnosis, Prognosis
Int6 Expression Can Predict Survival in Early-Stage Non–Small Cell Lung Cancer Patients
Fiamma Buttitta; Carla Martella; Fabio Barassi; Lara Felicioni; Simona Salvatore; Sandra Rosini; Tommaso D'Antuono; Antonio Chella; Felice Mucilli; Rocco Sacco; Andrea Mezzetti; Franco Cuccurullo; Robert Callahan; Antonio Marchetti
Serum Human Telomerase Reverse Transcriptase Messenger RNA as a Novel Tumor Marker for Hepatocellular Carcinoma
Norimasa Miura; Yoshiko Maeda; Takamasa Kanbe; Hiroaki Yazama; Yohei Takeda; Reina Sato; Tomoe Tsukamoto; Emi Sato; Akira Marumoto; Tomomi Harada; Akiko Sano; Yosuke Kishimoto; Yasuaki Hirooka; Yoshikazu Murawaki; Junichi Hasegawa; Goshi Shiota
Fluorodeoxyglucose Positron Emission Tomography as an Outcome Measure for Castrate Metastatic Prostate Cancer Treated with Antimicrotubule Chemotherapy
Michael J. Morris; Timothy Akhurst; Steven M. Larson; Marisa Ditullio; Elaina Chu; Karen Siedlecki; David Verbel; Glenn Heller; W. Kevin Kelly; Susan Slovin; Lawrence Schwartz; Howard I. Scher
Increased Expression of Insulin-Like Growth Factor I and/or Its Receptor in Gastrinomas Is Associated with Low Curability, Increased Growth, and Development of Metastases
Masayuki Furukawa; Mark Raffeld; Carmen Mateo; Akio Sakamoto; Terry W. Moody; Tetsuhide Ito; David J. Venzon; Jose Serrano; Robert T. Jensen
Expression of Cell Cycle–Regulated Proteins pRB2/p130, p107, E2F4, p27, and pCNA in Salivary Gland Tumors: Prognostic and Diagnostic Implications
Giuseppe Russo; Alessandra Zamparelli; Candace M. Howard; Corrado Minimo; Cristiana Bellan; Giovanna Carillo; Luigi Califano; Lorenzo Leoncini; Antonio Giordano; Pier Paolo Claudio
Prognostic Role of a Multigene Reverse Transcriptase-PCR Assay in Patients with Node-Negative Breast Cancer Not Receiving Adjuvant Systemic Therapy
Francisco J. Esteva; Aysegul A. Sahin; Massimo Cristofanilli; Kevin Coombes; Sang-Joon Lee; Joffre Baker; Maureen Cronin; Michael Walker; Drew Watson; Steven Shak; Gabriel N. Hortobagyi
YKL-40 Expression is Associated with Poorer Response to Radiation and Shorter Overall Survival in Glioblastoma
Christopher E. Pelloski; Anita Mahajan; Moshe Maor; Eric L. Chang; Shiao Woo; Mark Gilbert; Howard Colman; Helen Yang; Alicia Ledoux; Hilary Blair; Sandra Passe; Robert B. Jenkins; Kenneth D. Aldape
Cancer Therapy: Clinical
A Phase I Clinical Trial of Thoracic Radiotherapy and Concurrent Celecoxib for Patients with Unfavorable Performance Status Inoperable/Unresectable Non–Small Cell Lung Cancer
Zhongxing Liao; Ritsuko Komaki; Luka Milas; Chen Yuan; Merrill Kies; Joe Y. Chang; Melenda Jeter; Thomas Guerrero; George Blumenschien; Cheryl M. Smith; Frank Fossella; Barry Brown; James D. Cox
Combining a Recombinant Cancer Vaccine with Standard Definitive Radiotherapy in Patients with Localized Prostate Cancer
James L. Gulley; Philip M. Arlen; Anne Bastian; Steven Morin; Jennifer Marte; Patricia Beetham; Kwong-Yok Tsang; Junko Yokokawa; James W. Hodge; Cynthia Ménard; Kevin Camphausen; C. Norman Coleman; Francis Sullivan; Seth M. Steinberg; Jeffrey Schlom; William Dahut
A Multicenter Phase II Trial of ZD6474, a Vascular Endothelial Growth Factor Receptor-2 and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Previously Treated Metastatic Breast Cancer
Kathy D. Miller; Jose Manuel Trigo; Catherine Wheeler; Alan Barge; Jacqui Rowbottom; George Sledge; Jose Baselga
Phase I Pharmacokinetic-Pharmacodynamic Study of 17-(Allylamino)-17-Demethoxygeldanamycin (17AAG, NSC 330507), a Novel Inhibitor of Heat Shock Protein 90, in Patients with Refractory Advanced Cancers
Ramesh K. Ramanathan; Donald L. Trump; Julie L. Eiseman; Chandra P. Belani; Sanjiv S. Agarwala; Eleanor G. Zuhowski; Jing Lan; Douglas M. Potter; S. Percy Ivy; Sakkaraiappan Ramalingam; Adam M. Brufsky; Michael K.K. Wong; Susan Tutchko; Merrill J. Egorin
Enhanced Pharmacodynamic and Antitumor Properties of a Histone Deacetylase Inhibitor Encapsulated in Liposomes or ErbB2-Targeted Immunoliposomes
Daryl C. Drummond; Corina Marx; Zexiong Guo; Gary Scott; Charles Noble; Donghui Wang; Maria Pallavicini; John W. Park; Dmitri B. Kirpotin; Christopher C. Benz
Temozolomide Pharmacodynamics in Patients with Metastatic Melanoma: DNA Damage and Activity of Repair Enzymes O6-Alkylguanine Alkyltransferase and Poly(ADP-Ribose) Polymerase-1
E. Ruth Plummer; Mark R. Middleton; Christopher Jones; Anna Olsen; Ian Hickson; Peter McHugh; Geoffrey P. Margison; Gail McGown; Mary Thorncroft; Amanda J. Watson; Alan V. Boddy; A. Hilary Calvert; Adrian L. Harris; David R. Newell; Nicola J. Curtin
A Phase I and Pharmacologic Trial of Two Schedules of the Proteasome Inhibitor, PS-341 (Bortezomib, Velcade), in Patients with Advanced Cancer
Grace K. Dy; James P. Thomas; George Wilding; Laura Bruzek; Sumithra Mandrekar; Charles Erlichman; Dona Alberti; Kim Binger; Henry C. Pitot; Steven R. Alberts; Lorelei J. Hanson; Rebecca Marnocha; Kendra Tutsch; Scott H. Kaufmann; Alex A. Adjei
Phase I Trial of the Matrix Metalloproteinase Inhibitor Marimastat Combined with Carboplatin and Paclitaxel in Patients with Advanced Non–Small Cell Lung Cancer
John R. Goffin; Ian C. Anderson; Jeffrey G. Supko; Joseph Paul Eder, Jr.; Geoffrey I. Shapiro; Thomas J. Lynch; Margaret Shipp; Bruce E. Johnson; Arthur T. Skarin
Molecular Responses in Patients with Chronic Myelogenous Leukemia in Chronic Phase Treated with Imatinib Mesylate
Jorge Cortes; Moshe Talpaz; Susan O'Brien; Dan Jones; Rajyalakshmi Luthra; Jenny Shan; Francis Giles; Stefan Faderl; Srdan Verstovsek; Guillermo Garcia-Manero; Mary B. Rios; Hagop Kantarjian
Cancer Therapy: Preclinical
Resistance to the Tubulin-Binding Agents in Renal Cell Carcinoma: No Mutations in the Class I β-Tubulin Gene but Changes in Tubulin Isotype Protein Expression
Roisean E. Ferguson; Claire Taylor; Anthea Stanley; Elizabeth Butler; Adrian Joyce; Patricia Harnden; Poulam M. Patel; Peter J. Selby; Rosamonde E. Banks
Blockade of Paracrine Supply of Insulin-Like Growth Factors Using Neutralizing Antibodies Suppresses the Liver Metastasis of Human Colorectal Cancers
Shin'ichi Miyamoto; Michio Nakamura; Kenya Shitara; Kazuyasu Nakamura; Yuji Ohki; Genichiro Ishii; Masato Goya; Keiji Kodama; Takafumi Sangai; Hiroyuki Maeda; Zhang Shi-chuang; Tsutomu Chiba; Atsushi Ochiai
Metabolic Signatures Associated with a NAD Synthesis Inhibitor–Induced Tumor Apoptosis Identified by 1H-Decoupled-31P Magnetic Resonance Spectroscopy
Manickam Muruganandham; Alan A. Alfieri; Cornelia Matei; Yuchun Chen; George Sukenick; Isabel Schemainda; Max Hasmann; Leonard B. Saltz; Jason A. Koutcher
Differential Effects of Vascular Endothelial Growth Factor Receptor-2 Inhibitor ZD6474 on Circulating Endothelial Progenitors and Mature Circulating Endothelial Cells: Implications for Use as a Surrogate Marker of Antiangiogenic Activity
Paul Beaudry; Jeremy Force; George N. Naumov; Andrew Wang; Cheryl H. Baker; Anderson Ryan; Shay Soker; Bruce E. Johnson; Judah Folkman; John V. Heymach
Cancer Prevention
Expression of HOXB2, a Retinoic Acid Signaling Target in Pancreatic Cancer and Pancreatic Intraepithelial Neoplasia
Davendra Segara; Andrew V. Biankin; James G. Kench; Catherine C. Langusch; Amanda C. Dawson; David A. Skalicky; David C. Gotley; Maxwell J. Coleman; Robert L. Sutherland; Susan M. Henshall
Letters to the Editor
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