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Issues

Volume 11, Issue 4
15 February 2005
Clinical Cancer Research Cover Image for Volume 11, Issue 4
All Issues
ISSN 1078-0432
EISSN 1557-3265

The Biology Behind

Nucleotide Excision Repair, Oxidative Damage, DNA Sequence Polymorphisms, and Cancer Treatment
Stephanie Q. Hutsell; Aziz Sancar
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Editorial

Histologic Evaluation of Bronchial Squamous Lesions: Any Role in Lung Cancer Risk Assessment?
Ignacio I. Wistuba
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Perspective

Thrombopoietic Factors in Chronic Bone Marrow Failure States: The Platelet Problem Revisited
Razelle Kurzrock
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Human Cancer Biology

Somatic Mutations of Epidermal Growth Factor Receptor in Colorectal Carcinoma
Hisashi Nagahara; Koshi Mimori; Mitsuhiko Ohta; Tohru Utsunomiya; Hiroshi Inoue; Graham F. Barnard; Masaichi Ohira; Kosei Hirakawa; Masaki Mori
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Characterization of CEBPA Mutations in Acute Myeloid Leukemia: Most Patients with CEBPA Mutations Have Biallelic Mutations and Show a Distinct Immunophenotype of the Leukemic Cells
Liang-In Lin; Chien-Yuan Chen; Dong-Tsamn Lin; Woei Tsay; Jih-Luh Tang; You-Chia Yeh; Hwei-Ling Shen; Fang-Hsien Su; Ming Yao; Sheng-Yi Huang; Hwei-Fang Tien
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Down-Regulation of LATS1 and LATS2 mRNA Expression by Promoter Hypermethylation and Its Association with Biologically Aggressive Phenotype in Human Breast Cancers
Yuri Takahashi; Yasuo Miyoshi; Chie Takahata; Natsumi Irahara; Tetsuya Taguchi; Yasuhiro Tamaki; Shinzaburo Noguchi
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Expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Expression of Vascular Endothelial Growth Factor in and Angiogenic Phenotype of Human Gastric Cancer
Weida Gong; Liwei Wang; James C. Yao; Jaffer A. Ajani; Daoyan Wei; Kenneth D. Aldape; Keping Xie; Raymond Sawaya; Suyun Huang
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Imaging, Diagnosis, Prognosis

Prospective Study of Quantitation of Plasma DNA Levels in the Diagnosis of Malignant versus Benign Prostate Disease
Jane L. Boddy; Shira Gal; Peter R. Malone; Adrian L. Harris; Jim S. Wainscoat
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Alteration of Gene Expression in Macroscopically Normal Colonic Mucosa from Individuals with a Family History of Sporadic Colon Cancer
Chun-Yi Hao; Dan H. Moore; Patrick Wong; James L. Bennington; Nancy M. Lee; Ling-Chun Chen
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Nucleotide Excision Repair Gene Polymorphisms and Recurrence after Treatment for Superficial Bladder Cancer
Jian Gu; Hua Zhao; Colin P. Dinney; Yong Zhu; Dan Leibovici; Carlos E. Bermejo; H. Barton Grossman; Xifeng Wu
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Risk Assessment in Patients with Acute Myeloid Leukemia and a Normal Karyotype
Marianne Bienz; Madleina Ludwig; Beatrice U. Mueller; Elisabeth Oppliger Leibundgut; Daniel Ratschiller; Max Solenthaler; Martin F. Fey; Thomas Pabst
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Pathologic Assessment of Melanoma Sentinel Nodes: A Role for Molecular Analysis Using Quantitative Real-Time Reverse Transcription-PCR for MART-1 and Tyrosinase Messenger RNA
Helene Nortvig Abrahamsen; Boe Sandahl Sorensen; Ebba Nexo; Stephen J. Hamilton-Dutoit; Jørn Larsen; Torben Steiniche
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Prognostic Significance of Vascular Endothelial Growth Factor Immunohistochemical Expression in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis
Panayiotis A. Kyzas; Isabella W. Cunha; John P.A. Ioannidis
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Serum Mannan-Binding Lectin-Associated Serine Protease 2 Levels in Colorectal Cancer: Relation to Recurrence and Mortality
Henriette Ytting; Ib Jarle Christensen; Steffen Thiel; Jens Christian Jensenius; Hans Jørgen Nielsen
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Combined Evaluation of Expressions of Cyclin E and p53 Proteins as Prognostic Factors for Patients with Gastric Cancer
Kamal E. Bani-Hani; Nidal M. Almasri; Yousef S. Khader; Fawzi M. Sheyab; Hanan N. Karam
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An 19F Magnetic Resonance–Based In Vivo Assay of Solid Tumor Methotrexate Resistance: Proof of Principle
William M. Spees; Terence P.F. Gade; Guangli Yang; William P. Tong; William G. Bornmann; Richard Gorlick; Jason A. Koutcher
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Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients
Amy B. Heimberger; Roman Hlatky; Dima Suki; David Yang; Jeff Weinberg; Mark Gilbert; Raymond Sawaya; Kenneth Aldape
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Outcome in Hodgkin's Lymphoma Can Be Predicted from the Presence of Accompanying Cytotoxic and Regulatory T Cells
Tomás Álvaro; Marylène Lejeune; Ma Teresa Salvadó; Ramón Bosch; Juan F. García; Joaquín Jaén; Alison H. Banham; Giovanna Roncador; Carlos Montalbán; Miguel A. Piris
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Cancer Therapy: Clinical

A Potent Immunogenic General Cancer Vaccine That Targets Survivin, an Inhibitor of Apoptosis Proteins
Satomi Idenoue; Yoshihiko Hirohashi; Toshihiko Torigoe; Yuriko Sato; Yasuaki Tamura; Hiroyuki Hariu; Masaaki Yamamoto; Takehiro Kurotaki; Tetsuhiro Tsuruma; Hiroko Asanuma; Takayuki Kanaseki; Hideyuki Ikeda; Kiyoteru Kashiwagi; Minoru Okazaki; Kazuaki Sasaki; Takashi Sato; Tousei Ohmura; Fumitake Hata; Koji Yamaguchi; Koichi Hirata; Noriyuki Sato
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In vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts after MUC1-Driven Expression of the Sodium Iodide Symporter
Roisin M. Dwyer; Elizabeth R. Bergert; Michael K. O'Connor; Sandra J. Gendler; John C. Morris
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B-Cell Lymphomas Differ in their Responsiveness to CpG Oligodeoxynucleotides
Bernd Jahrsdorfer; Lars Mühlenhoff; Sue E. Blackwell; Moritz Wagner; Hendrik Poeck; Evelyn Hartmann; Ralf Jox; Thomas Giese; Bertold Emmerich; Stefan Endres; George J. Weiner; Gunther Hartmann
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Endocrine Effects of Tamoxifen Plus Exemestane in Postmenopausal Women with Breast Cancer
Richard R. Love; Paul R. Hutson; Thomas C. Havighurst; James F. Cleary
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Phase I Pharmacokinetic, Food Effect, and Pharmacogenetic Study of Oral Irinotecan Given as Semisolid Matrix Capsules in Patients with Solid Tumors
Otto Soepenberg; Herlinde Dumez; Jaap Verweij; Floris A. de Jong; Maja J.A. de Jonge; José Thomas; Ferry A.L.M. Eskens; Ron H.N. van Schaik; Johan Selleslach; Judith ter Steeg; Patricia Lefebvre; Sylvie Assadourian; Ger-Jan Sanderink; Alex Sparreboom; Allan T. van Oosterom
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Phase I Study of MetXia-P450 Gene Therapy and Oral Cyclophosphamide for Patients with Advanced Breast Cancer or Melanoma
Jeremy P. Braybrooke; Andrew Slade; Gael Deplanque; Richard Harrop; Srinivasan Madhusudan; Martin D. Forster; Rachel Gibson; Andreas Makris; Denis C. Talbot; Jan Steiner; Linda White; On Kan; Stuart Naylor; Miles W. Carroll; Sue M. Kingsman; Adrian L. Harris
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T Cell–Dependent Antibody Responses against Aberrantly Expressed Cyclin B1 Protein in Patients with Cancer and Premalignant Disease
Hiroyuki Suzuki; Daniel F. Graziano; John McKolanis; Olivera J. Finn
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Phase I Trial of Combretastatin A-4 Phosphate with Carboplatin
Joshua H. Bilenker; Keith T. Flaherty; Mark Rosen; Lisa Davis; Maryann Gallagher; James P. Stevenson; Weijing Sun; David Vaughn; Bruce Giantonio; Ross Zimmer; Mitchell Schnall; Peter J. O'Dwyer
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Polymorphisms in ERCC1 and Grade 3 or 4 Toxicity in Non–Small Cell Lung Cancer Patients
Rebecca Suk; Sarada Gurubhagavatula; Sohee Park; Wei Zhou; Li Su; Thomas J. Lynch; John C. Wain; Donna Neuberg; Geoffrey Liu; David C. Christiani
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Promoter Hypermethylation of Mismatch Repair Gene hMLH1 Predicts the Clinical Response of Malignant Astrocytomas to Nitrosourea
Takao Fukushima; Yoichi Katayama; Takao Watanabe; Atsuo Yoshino; Akiyoshi Ogino; Takashi Ohta; Chiaki Komine
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Cancer Therapy: Preclinical

HA22 (R490A) Is a Recombinant Immunotoxin with Increased Antitumor Activity without an Increase in Animal Toxicity
SookHee Bang; Satoshi Nagata; Masanori Onda; Robert J. Kreitman; Ira Pastan
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Antitumor Effects of a Monoclonal Antibody that Binds Anionic Phospholipids on the Surface of Tumor Blood Vessels in Mice
Sophia Ran; Jin He; Xianming Huang; Melina Soares; Douglas Scothorn; Philip E. Thorpe
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The Insulin-Like Growth Factor-I Receptor Kinase Inhibitor, NVP-ADW742, Sensitizes Small Cell Lung Cancer Cell Lines to the Effects of Chemotherapy
G. Sakuntala Warshamana-Greene; Julie Litz; Elisabeth Buchdunger; Carlos García-Echeverría; Francesco Hofmann; Geoffrey W. Krystal
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Enhanced Sensitivity to the HER1/Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib Hydrochloride in Chemotherapy-Resistant Tumor Cell Lines
Qun Dai; Yi-He Ling; Marie Lia; Yi-Yu Zou; Glenn Kroog; Kenneth K. Iwata; Roman Perez-Soler
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In vitro Canine Distemper Virus Infection of Canine Lymphoid Cells: A Prelude to Oncolytic Therapy for Lymphoma
Steven E. Suter; May B. Chein; Veronika von Messling; Becky Yip; Roberto Cattaneo; William Vernau; Bruce R. Madewell; Cheryl A. London
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Patupilone Acts as Radiosensitizing Agent in Multidrug-Resistant Cancer Cells In vitro and In vivo
Barbara Hofstetter; Van Vuong; Angela Broggini-Tenzer; Stephan Bodis; Ilja F. Ciernik; Doriano Fabbro; Markus Wartmann; Gerd Folkers; Martin Pruschy
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Analyses of Recombinant Vaccinia and Fowlpox Vaccine Vectors Expressing Transgenes for Two Human Tumor Antigens and Three Human Costimulatory Molecules
Kwong Y. Tsang; Claudia Palena; Junko Yokokawa; Philip M. Arlen; James L. Gulley; Gail P. Mazzara; Linda Gritz; Alicia Gómez Yafal; Sandra Ogueta; Patricia Greenhalgh; Kelledy Manson; Dennis Panicali; Jeffrey Schlom
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Formation and Antitumor Activity of PNU-159682, A Major Metabolite of Nemorubicin in Human Liver Microsomes
Luigi Quintieri; Cristina Geroni; Marianna Fantin; Rosangela Battaglia; Antonio Rosato; William Speed; Paola Zanovello; Maura Floreani
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Effects of Nonselective Cyclooxygenase Inhibition with Low-Dose Ibuprofen on Tumor Growth, Angiogenesis, Metastasis, and Survival in a Mouse Model of Colorectal Cancer
Min Yao; Wei Zhou; Simren Sangha; Andrew Albert; Albert J. Chang; Thomas C. Liu; M. Michael Wolfe
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Identification of CD19 and CD20 Peptides for Induction of Antigen-Specific CTLs against B-Cell Malignancies
Jooeun Bae; Jeffrey A. Martinson; Hans G. Klingemann
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Induction of T-Cell Apoptosis in Rats by Genetically Engineered Glioma Cells Expressing Granulocyte-Macrophage Colony-Stimulating Factor and B7.1
Sheng-Hong Tseng; Yun Chen; Chun-Jung Chang; Kuo-Feng Tai; Swei-Ming Lin; Lih-Hwa Hwang
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MEN4901/T-0128, a New Camptothecin Derivative–Carboxymethyldextran Conjugate, Has Potent Antitumor Activities in a Panel of Human Tumor Xenografts in Nude Mice
Fumiko Fujita; Masako Koike; Masahide Fujita; Yasuo Sakamoto; Satoshi Okuno; Takayuki Kawaguchi; Shigeru Yano; Toshiro Yano; Satoko Kiuchi; Toshihisa Fujiwara; Shinzoh Kudoh; Masatoshi Kakushima
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Photochemical Targeting of Epidermal Growth Factor Receptor: A Mechanistic Study
Mark D. Savellano; Tayyaba Hasan
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Plasma and Cerebrospinal Fluid Pharmacokinetics of Intravenous Oxaliplatin, Cisplatin, and Carboplatin in Nonhuman Primates
Shana S. Jacobs; Elizabeth Fox; Christopher Dennie; Lindsey B. Morgan; Cynthia L. McCully; Frank M. Balis
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Green Tea Extract Modulates Actin Remodeling via Rho Activity in an In vitro Multistep Carcinogenic Model
Qing-Yi Lu; Yu-Sheng Jin; Allan Pantuck; Zuo-Feng Zhang; David Heber; Arie Belldegrun; Mai Brooks; Robert Figlin; JianYu Rao
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Corrections

Correction: Article on the In vitro and In vivo Effects of Re-expressing Methylated von Hippel-Lindau Tumor Suppressor Gene with 5-Aza-dCyd
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Correction: Article on the Characterization and Multiparameter Analysis of Visual Adverse Events in Irofulven Single-Agent Phase I and II Trials
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  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

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