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Issues

Volume 11, Issue 22
15 November 2005
Issue Cover
All Issues
ISSN 1078-0432
EISSN 1557-3265

Editorial

Irrational Exuberance in Clinical Proteomics
Simon M. Lin; Warren Alden Kibbe
View articletitled, Irrational Exuberance in Clinical Proteomics
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The Biology Behind

Phosphatidylinositol 3-Kinase Inhibitors Are a Triple Threat to Ovarian Cancer
Ramon Parsons
View articletitled, Phosphatidylinositol 3-Kinase Inhibitors Are a Triple Threat to Ovarian Cancer
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Review

The Progress and Promise of Molecular Imaging Probes in Oncologic Drug Development
Gary J. Kelloff; Kenneth A. Krohn; Steven M. Larson; Ralph Weissleder; David A. Mankoff; John M. Hoffman; Jeanne M. Link; Kathryn Z. Guyton; William C. Eckelman; Howard I. Scher; Joyce O'Shaughnessy; Bruce D. Cheson; Caroline C. Sigman; James L. Tatum; George Q. Mills; Daniel C. Sullivan; Janet Woodcock
View articletitled, The Progress and Promise of Molecular Imaging Probes in Oncologic Drug Development
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Human Cancer Biology

Clear Cell Sarcoma of the Kidney: Up-regulation of Neural Markers with Activation of the Sonic Hedgehog and Akt Pathways
Colleen Cutcliffe; Donna Kersey; Chiang-Ching Huang; Yong Zeng; David Walterhouse; Elizabeth J. Perlman; for the Renal Tumor Committee of the Children's Oncology Group
View articletitled, Clear Cell Sarcoma of the Kidney: Up-regulation of Neural Markers with Activation of the Sonic Hedgehog and Akt Pathways
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Heparanase Is Involved in Angiogenesis in Esophageal Cancer through Induction of Cyclooxygenase-2
Takaomi Okawa; Yoshio Naomoto; Tetsuji Nobuhisa; Munenori Takaoka; Takayuki Motoki; Yasuhiro Shirakawa; Tomoki Yamatsuji; Hiroyasu Inoue; Mamoru Ouchida; Mehmet Gunduz; Motowo Nakajima; Noriaki Tanaka
View articletitled, Heparanase Is Involved in Angiogenesis in Esophageal Cancer through Induction of Cyclooxygenase-2
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Changes in Cytoskeletal Protein Composition Indicative of an Epithelial-Mesenchymal Transition in Human Micrometastatic and Primary Breast Carcinoma Cells
Birthe Willipinski-Stapelfeldt; Sabine Riethdorf; Volker Assmann; Ute Woelfle; Thomas Rau; Guido Sauter; Jochen Heukeshoven; Klaus Pantel
View articletitled, Changes in Cytoskeletal Protein Composition Indicative of an Epithelial-Mesenchymal Transition in Human Micrometastatic and Primary Breast Carcinoma Cells
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Androgen Mediation of Thrombocytosis in Epithelial Ovarian Cancer Biology
Andrew John Li; Beth Young Karlan
View articletitled, Androgen Mediation of Thrombocytosis in Epithelial Ovarian Cancer Biology
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Overexpression of the Cytokine Osteopontin Identifies Aggressive Laryngeal Squamous Cell Carcinomas and Enhances Carcinoma Cell Proliferation and Invasiveness
Angela Celetti; Domenico Testa; Stefania Staibano; Francesco Merolla; Valentina Guarino; Maria Domenica Castellone; Renata Iovine; Gelsomina Mansueto; Pasquale Somma; Gaetano De Rosa; Vieri Galli; Rosa Marina Melillo; Massimo Santoro
View articletitled, Overexpression of the Cytokine Osteopontin Identifies Aggressive Laryngeal Squamous Cell Carcinomas and Enhances Carcinoma Cell Proliferation and Invasiveness
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Estrogen Signaling Is Active in Cartilaginous Tumors: Implications for Antiestrogen Therapy as Treatment Option of Metastasized or Irresectable Chondrosarcoma
Anne-Marie Cleton-Jansen; Hetty M. van Beerendonk; Hans J. Baelde; Judith V.G.M. Bovée; Marcel Karperien; Pancras C.W. Hogendoorn
View articletitled, Estrogen Signaling Is Active in Cartilaginous Tumors: Implications for Antiestrogen Therapy as Treatment Option of Metastasized or Irresectable Chondrosarcoma
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Positive Correlation between Estradiol and Vascular Endothelial Growth Factor but not Fibroblast Growth Factor-2 in Normal Human Breast Tissue In vivo
Charlotta Dabrosin
View articletitled, Positive Correlation between Estradiol and Vascular Endothelial Growth Factor but not Fibroblast Growth Factor-2 in Normal Human Breast Tissue <em>In vivo</em>
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Imaging, Diagnosis, Prognosis

Possible Prediction of Chemoradiosensitivity of Esophageal Cancer by Serum Protein Profiling
Yasuharu Hayashida; Kazufumi Honda; Yoshiaki Osaka; Tomohiko Hara; Tomoko Umaki; Akihiko Tsuchida; Tatsuya Aoki; Setsuo Hirohashi; Tesshi Yamada
View articletitled, Possible Prediction of Chemoradiosensitivity of Esophageal Cancer by Serum Protein Profiling
Supplementary data
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Specialized DNA Arrays for the Differentiation of Pancreatic Tumors
Malte Buchholz; Hans A. Kestler; Andrea Bauer; Wolfgang Böck; Bettina Rau; Gerhard Leder; Wolfgang Kratzer; Martin Bommer; Aldo Scarpa; Martin K. Schilling; Guido Adler; Jörg D. Hoheisel; Thomas M. Gress
View articletitled, Specialized DNA Arrays for the Differentiation of Pancreatic Tumors
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Cancer-Testis Genes Are Coordinately Expressed and Are Markers of Poor Outcome in Non–Small Cell Lung Cancer
Ali O. Gure; Ramon Chua; Barbara Williamson; Mithat Gonen; Cathy A. Ferrera; Sacha Gnjatic; Gerd Ritter; Andrew J.G. Simpson; Yao-T. Chen; Lloyd J. Old; Nasser K. Altorki
View articletitled, Cancer-Testis Genes Are Coordinately Expressed and Are Markers of Poor Outcome in Non–Small Cell Lung Cancer
Supplementary data
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Increased Expression of Vascular Endothelial Growth Factor C in Papillary Thyroid Carcinoma Correlates with Cervical Lymph Node Metastases
Xiao-Min Yu; Chung-Yau Lo; Wai-Fan Chan; King-Yin Lam; Pauline Leung; John M. Luk
View articletitled, Increased Expression of Vascular Endothelial Growth Factor C in Papillary Thyroid Carcinoma Correlates with Cervical Lymph Node Metastases
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Transcription Repressor Slug Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
Jin-Yuan Shih; Meng-Feng Tsai; Tzu-Hua Chang; Yih-Leong Chang; Ang Yuan; Chong-Jen Yu; Shin-Bey Lin; Geou-Yarh Liou; Meng-Larn Lee; Jeremy J.W. Chen; Tse-Ming Hong; Shuenn-Chen Yang; Jen-Liang Su; Yung-Chie Lee; Pan-Chyr Yang
View articletitled, Transcription Repressor <em>Slug</em> Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
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Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels
Yoshiaki Ikuta; Tetsuya Nakatsura; Toshiro Kageshita; Satoshi Fukushima; Shosuke Ito; Kazumasa Wakamatsu; Hideo Baba; Yasuharu Nishimura
View articletitled, Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels
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Cancer Therapy: Clinical

Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia
Peter D. Cole; Richard A. Drachtman; Angela K. Smith; Sarah Cate; Richard A. Larson; Douglas S. Hawkins; John Holcenberg; Kara Kelly; Barton A. Kamen
View articletitled, Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia
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Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 Polymorphisms with the Pharmacokinetics of Paclitaxel
Anja Henningsson; Sharon Marsh; Walter J. Loos; Mats O. Karlsson; Adam Garsa; Klaus Mross; Stephan Mielke; Lucia Viganò; Alberta Locatelli; Jaap Verweij; Alex Sparreboom; Howard L. McLeod
View articletitled, Association of <em>CYP2C8, CYP3A4, CYP3A5</em>, and <em>ABCB1</em> Polymorphisms with the Pharmacokinetics of Paclitaxel
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Response of Some Head and Neck Cancers to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors May Be Linked to Mutation of ERBB2 rather than EGFR
Ezra E.W. Cohen; Mark W. Lingen; Leslie E. Martin; Patricia L. Harris; Brian W. Brannigan; Sara M. Haserlat; Ross A. Okimoto; Dennis C. Sgroi; Sonika Dahiya; Beth Muir; John R. Clark; James W. Rocco; Everett E. Vokes; Daniel A. Haber; Daphne W. Bell
View articletitled, Response of Some Head and Neck Cancers to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors May Be Linked to Mutation of <em>ERBB2</em> rather than <em>EGFR</em>
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Predictors of Prostate Cancer Tissue Acquisition by an Undirected Core Bone Marrow Biopsy in Metastatic Castration-Resistant Prostate Cancer—A Cancer and Leukemia Group B Study
Robert W. Ross; Susan Halabi; San-San Ou; Barur R. Rajeshkumar; Bruce A. Woda; Nicholas J. Vogelzang; Eric J. Small; Mary-Ellen Taplin; Philip W. Kantoff
View articletitled, Predictors of Prostate Cancer Tissue Acquisition by an Undirected Core Bone Marrow Biopsy in Metastatic Castration-Resistant Prostate Cancer—A Cancer and Leukemia Group B Study
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Cancer Therapy: Preclinical

Comparison of Two Cancer Vaccines Targeting Tyrosinase: Plasmid DNA and Recombinant Alphavirus Replicon Particles
Stacie M. Goldberg; Shirley M. Bartido; Jason P. Gardner; José A. Guevara-Patiño; Stephanie C. Montgomery; Miguel-Angel Perales; Maureen F. Maughan; JoAnn Dempsey; Gerald P. Donovan; William C. Olson; Alan N. Houghton; Jedd D. Wolchok
View articletitled, Comparison of Two Cancer Vaccines Targeting Tyrosinase: Plasmid DNA and Recombinant Alphavirus Replicon Particles
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Inhibition of the Met Receptor in Mesothelioma
Toru Mukohara; Gabriel Civiello; Ian J. Davis; Michele L. Taffaro; James Christensen; David E. Fisher; Bruce E. Johnson; Pasi A. Jänne
View articletitled, Inhibition of the Met Receptor in Mesothelioma
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Combination Bcl-2 Antisense and Radiation Therapy for Nasopharyngeal Cancer
Kenneth W. Yip; Joseph D. Mocanu; P.Y. Billie Au; Gillian T. Sleep; Dolly Huang; Pierre Busson; Wen-Chen Yeh; Ralph Gilbert; Brian O'Sullivan; Patrick Gullane; Carlo Bastianutto; Fei-Fei Liu
View articletitled, Combination Bcl-2 Antisense and Radiation Therapy for Nasopharyngeal Cancer
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ZD6474, a Novel Tyrosine Kinase Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor, Inhibits Tumor Growth of Multiple Nervous System Tumors
Jeremy N. Rich; Sith Sathornsumetee; Stephen T. Keir; Mark W. Kieran; Andrea Laforme; Arja Kaipainen; Roger E. McLendon; Michael W. Graner; B.K. Ahmed Rasheed; Ling Wang; David A. Reardon; Anderson J. Ryan; Catherine Wheeler; Isaiah Dimery; Darell D. Bigner; Henry S. Friedman
View articletitled, ZD6474, a Novel Tyrosine Kinase Inhibitor of Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor, Inhibits Tumor Growth of Multiple Nervous System Tumors
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Roscovitine Modulates DNA Repair and Senescence: Implications for Combination Chemotherapy
Elvira Crescenzi; Giuseppe Palumbo; Hugh J.M. Brady
View articletitled, Roscovitine Modulates DNA Repair and Senescence: Implications for Combination Chemotherapy
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Heparin Octasaccharides Inhibit Angiogenesis In vivo
Jurjees Hasan; Steven D. Shnyder; Andrew R. Clamp; Alan T. McGown; Roy Bicknell; Marco Presta; Michael Bibby; John Double; Steven Craig; David Leeming; Kenneth Stevenson; John T. Gallagher; Gordon C. Jayson
View articletitled, Heparin Octasaccharides Inhibit Angiogenesis <em>In vivo</em>
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Intraperitoneal Pretarget Radioimmunotherapy with CC49 Fusion Protein
Donald J. Buchsbaum; M.B. Khazaeli; Donald B. Axworthy; Jody Schultz; Tandra R. Chaudhuri; Kurt R. Zinn; Mark Carpenter; Albert F. LoBuglio
View articletitled, Intraperitoneal Pretarget Radioimmunotherapy with CC49 Fusion Protein
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Inhibition of Nuclear Translocation of Nuclear Factor-κB Despite Lack of Functional IκBα Protein Overcomes Multiple Defects in Apoptosis Signaling in Human B-Cell Malignancies
Roman K. Thomas; Martin L. Sos; Thomas Zander; Özlem Mani; Alexey Popov; Daniel Berenbrinker; Sigrun Smola-Hess; Joachim L. Schultze; Jürgen Wolf
View articletitled, Inhibition of Nuclear Translocation of Nuclear Factor-κB Despite Lack of Functional IκBα Protein Overcomes Multiple Defects in Apoptosis Signaling in Human B-Cell Malignancies
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Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy
Licun Wu; Ian F. Tannock
View articletitled, Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy
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Carbonic Anhydrase II Is a Tumor Vessel Endothelium–Associated Antigen Targeted by Dendritic Cell Therapy
Kenta Yoshiura; Takashi Nakaoka; Toshihide Nishishita; Katsuaki Sato; Akifumi Yamamoto; Shinji Shimada; Toshiaki Saida; Yutaka Kawakami; Tsuneo A. Takahashi; Hiroyuki Fukuda; Shinobu Imajoh-Ohmi; Naoki Oyaizu; Naohide Yamashita
View articletitled, Carbonic Anhydrase II Is a Tumor Vessel Endothelium–Associated Antigen Targeted by Dendritic Cell Therapy
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Phosphatidylinostol 3-Kinase Mediates Angiogenesis and Vascular Permeability Associated with Ovarian Carcinoma
Limin Hu; Judith Hofmann; Robert B. Jaffe
View articletitled, Phosphatidylinostol 3-Kinase Mediates Angiogenesis and Vascular Permeability Associated with Ovarian Carcinoma
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Cancer Prevention

In vitro and In vivo Effects and Mechanisms of Celecoxib-Induced Growth Inhibition of Human Hepatocellular Carcinoma Cells
Wei Cui; Chang-Hong Yu; Ke-Qin Hu
View articletitled, <em>In vitro</em> and <em>In vivo</em> Effects and Mechanisms of Celecoxib-Induced Growth Inhibition of Human Hepatocellular Carcinoma Cells
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Letters to the Editor

The Estrogen Receptors α, β, and βcx
Abeer M. Shaaban; Valerie Speirs
View articletitled, The Estrogen Receptors α, β, and βcx
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Correction

Article on Sodium Channels and Breast Cancer Metastasis
View articletitled, Article on Sodium Channels and Breast Cancer Metastasis
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  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

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