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Perspective

Concepts for Banking Tissue in Urologic Oncology—The International Bladder Cancer Bank

Peter J. Goebell; Susan Groshen; Bernd J. Schmitz-Dräger; Richard Sylvester; Manolis Kogevinas; Núria Malats; Guido Sauter; H. Barton Grossman; Colin P.N. Dinney; Fred Waldman; Richard J. Cote

Extract

View articletitled, Concepts for Banking Tissue in Urologic Oncology—The International Bladder Cancer Bank

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Differentiation and Definition of Vascular-Targeted Therapies

Dietmar W. Siemann; Michael C. Bibby; Graham G. Dark; Adam P. Dicker; Ferry A.L.M. Eskens; Michael R. Horsman; Dieter Marmé; Patricia M. LoRusso

Abstract

View articletitled, Differentiation and Definition of Vascular-Targeted Therapies

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Cooperative Group Bulletin Board

New Frontiers in Translational Research in Neuro-oncology and the Blood-Brain Barrier: Report of the Tenth Annual Blood-Brain Barrier Disruption Consortium Meeting

Nancy D. Doolittle; Lauren E. Abrey; W. Archie Bleyer; Steven Brem; Thomas P. Davis; Paula Dore-Duffy; Lester R. Drewes; Walter A. Hall; John M. Hoffman; Agnieszka Korfel; Robert Martuza; Leslie L. Muldoon; David Peereboom; Darryl R. Peterson; Samuel D. Rabkin; Quentin Smith; Glen H.J. Stevens; Edward A. Neuwelt

Abstract

View articletitled, New Frontiers in Translational Research in Neuro-oncology and the Blood-Brain Barrier: Report of the Tenth Annual Blood-Brain Barrier Disruption Consortium Meeting

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Human Cancer Biology

Geranylgeranylated Proteins are Involved in the Regulation of Myeloma Cell Growth

Niels W.C.J. van de Donk; Henk M. Lokhorst; Evert H.J. Nijhuis; Marloes M.J. Kamphuis; Andries C. Bloem

Abstract

View articletitled, Geranylgeranylated Proteins are Involved in the Regulation of Myeloma Cell Growth

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Overexpression of Tropomysin-Related Kinase B in Metastatic Human Pancreatic Cancer Cells

Guido M. Sclabas; Shuichi Fujioka; Christian Schmidt; Zhongkui Li; Wayne A.I. Frederick; Wentao Yang; Kenji Yokoi; Douglas B. Evans; James L. Abbruzzese; Kenneth R. Hess; Wei Zhang; Isaiah J. Fidler; Paul J. Chiao

Abstract

View articletitled, Overexpression of Tropomysin-Related Kinase B in Metastatic Human Pancreatic Cancer Cells

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Aberrant Expression of Human Achaete-Scute Homologue Gene 1 in the Gastrointestinal Neuroendocrine Carcinomas

Takashi Shida; Mitsuko Furuya; Takashi Nikaido; Takashi Kishimoto; Keiji Koda; Kenji Oda; Yukio Nakatani; Masaru Miyazaki; Hiroshi Ishikura

Abstract

View articletitled, Aberrant Expression of Human Achaete-Scute Homologue Gene 1 in the Gastrointestinal Neuroendocrine Carcinomas

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Fibroblast Growth Factor Receptor 3 Is Overexpressed in Urinary Tract Carcinomas and Modulates the Neoplastic Cell Growth

J. Javier Gómez-Román; Pilar Saenz; Jorge Cuevas González; Kepa Escuredo; Simon Santa Cruz; Corina Junquera; Laureano Simón; Antonio Martínez; J. Luis Gutiérrez Baños; Marta López-Brea; Clara Esparza; J. Fernando Val-Bernal

Abstract

View articletitled, Fibroblast Growth Factor Receptor 3 Is Overexpressed in Urinary Tract Carcinomas and Modulates the Neoplastic Cell Growth

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Plasma Adiponectin and Gastric Cancer

Makoto Ishikawa; Joji Kitayama; Shinsuke Kazama; Takeyuki Hiramatsu; Kenji Hatano; Hirokazu Nagawa

Abstract

View articletitled, Plasma Adiponectin and Gastric Cancer

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Identification of Gastric Cancer–Related Genes Using a cDNA Microarray Containing Novel Expressed Sequence Tags Expressed in Gastric Cancer Cells

Jeong-Min Kim; Ho-Yong Sohn; Sun Young Yoon; Jung-Hwa Oh; Jin Ok Yang; Joo Heon Kim; Kyu Sang Song; Seung-Moo Rho; Hyan Sook Yoo; Yong Sung Kim; Jong-Guk Kim; Nam-Soon Kim

Abstract

View articletitled, Identification of Gastric Cancer–Related Genes Using a cDNA Microarray Containing Novel Expressed Sequence Tags Expressed in Gastric Cancer Cells

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Alternative mRNA Splicing of Liver Intestine-Cadherin in Hepatocellular Carcinoma

Xiao Qi Wang; John M. Luk; Pauline P. Leung; Bonnie W. Wong; Eric J. Stanbridge; Sheung Tat Fan

Abstract

View articletitled, Alternative mRNA Splicing of Liver Intestine-Cadherin in Hepatocellular Carcinoma

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Involvement of Chemokine Receptor 4/Stromal Cell–Derived Factor 1 System during Osteosarcoma Tumor Progression

Eliana Perissinotto; Giuliana Cavalloni; Francesco Leone; Valentina Fonsato; Stefania Mitola; Giovanni Grignani; Nadia Surrenti; Dario Sangiolo; Federico Bussolino; Wanda Piacibello; Massimo Aglietta

Abstract

View articletitled, Involvement of Chemokine Receptor 4/Stromal Cell–Derived Factor 1 System during Osteosarcoma Tumor Progression

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Control of T-Cell–Mediated Immune Response by HLA Class I in Human Pancreatic Carcinoma

Eduard Ryschich; Tanja Nötzel; Ulf Hinz; Frank Autschbach; James Ferguson; Ioan Simon; Jürgen Weitz; Boris Fröhlich; Ernst Klar; Markus W. Büchler; Jan Schmidt

Abstract

View articletitled, Control of T-Cell–Mediated Immune Response by HLA Class I in Human Pancreatic Carcinoma

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CD34⁺CD7⁺ Leukemic Progenitor Cells May Be Involved in Maintenance and Clonal Evolution of Chronic Myeloid Leukemia

Nobuharu Kosugi; Yasuhiro Ebihara; Tatsutoshi Nakahata; Hiromitsu Saisho; Shigetaka Asano; Arinobu Tojo

Abstract

View articletitled, CD34+CD7+ Leukemic Progenitor Cells May Be Involved in Maintenance and Clonal Evolution of Chronic Myeloid Leukemia

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Mutations and Deletions of the CBP Gene in Human Lung Cancer

Masahiro Kishimoto; Takashi Kohno; Koji Okudela; Ayaka Otsuka; Hiroki Sasaki; Chikako Tanabe; Tokuki Sakiyama; Chie Hirama; Issay Kitabayashi; John D. Minna; Seiichi Takenoshita; Jun Yokota

Abstract

View articletitled, Mutations and Deletions of the CBP Gene in Human Lung Cancer

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Imaging, Diagnosis, Prognosis

Expression and Signaling Activity of Wnt-5a/Discoidin Domain Receptor-1 and Syk Plays Distinct but Decisive Roles in Breast Cancer Patient Survival

Janna Dejmek; Karin Leandersson; Jonas Manjer; Anders Bjartell; Stefan O. Emdin; Wolfgang F. Vogel; Göran Landberg; Tommy Andersson

Abstract

View articletitled, Expression and Signaling Activity of Wnt-5a/Discoidin Domain Receptor-1 and Syk Plays Distinct but Decisive Roles in Breast Cancer Patient Survival

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The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging

Bénédicte F. Jordan; Matthew Runquist; Natarajan Raghunand; Robert J. Gillies; Wendy R. Tate; Garth Powis; Amanda F. Baker

Abstract

View articletitled, The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging

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The Natural Course of Preneoplastic Lesions in Bronchial Epithelium

Roderick H. Breuer; Arifa Pasic; Egbert F. Smit; Esther van Vliet; Anton Vonk Noordegraaf; Elle J. Risse; Pieter E. Postmus; Thomas G. Sutedja

Abstract

View articletitled, The Natural Course of Preneoplastic Lesions in Bronchial Epithelium

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Tartrate-Resistant Acid Phosphatase 5b is a Useful Serum Marker for Extensive Bone Metastasis in Breast Cancer Patients

Tsu-Yi Chao; Jyh-Cherng Yu; Chih-Hung Ku; Mary M. Chen; Su-Huei Lee; Anthony J. Janckila; Lung T. Yam

Abstract

View articletitled, Tartrate-Resistant Acid Phosphatase 5b is a Useful Serum Marker for Extensive Bone Metastasis in Breast Cancer Patients

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Claudin-10 Expression Level is Associated with Recurrence of Primary Hepatocellular Carcinoma

Siu Tim Cheung; Ka Ling Leung; Ying Chi Ip; Xin Chen; Daniel Y. Fong; Irene O. Ng; Sheung Tat Fan; Samuel So

Abstract

View articletitled, Claudin-10 Expression Level is Associated with Recurrence of Primary Hepatocellular Carcinoma

Supplementary data

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Methylation of the γ-Catenin Gene Is Associated With Poor Prognosis of Renal Cell Carcinoma

Julia E. Breault; Hiroaki Shiina; Mikio Igawa; Leopoldo A. Ribeiro-Filho; Masao Deguchi; Hideki Enokida; Shinji Urakami; Masaharu Terashima; Masayuki Nakagawa; Christopher J. Kane; Peter R. Carroll; Rajvir Dahiya

Abstract

View articletitled, Methylation of the γ-Catenin Gene Is Associated With Poor Prognosis of Renal Cell Carcinoma

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Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays

Abstract

View articletitled, Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays

Supplementary data

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Age- and Disease-Related Methylation of Multiple Genes in Nonneoplastic Duodenum and in Duodenal Juice

Hiroyuki Matsubayashi; Norihiro Sato; Kieran Brune; Amanda Lapides Blackford; Ralph H. Hruban; Marcia Canto; Charles J. Yeo; Michael Goggins

Abstract

View articletitled, Age- and Disease-Related Methylation of Multiple Genes in Nonneoplastic Duodenum and in Duodenal Juice

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Stage-Specific Characterization of the Vascular Endothelial Growth Factor Axis in Prostate Cancer: Expression of Lymphangiogenic Markers Is Associated with Advanced-Stage Disease

Varsha Kaushal; Perkins Mukunyadzi; Richard A. Dennis; Eric R. Siegel; Donald E. Johnson; Manish Kohli

Abstract

View articletitled, Stage-Specific Characterization of the Vascular Endothelial Growth Factor Axis in Prostate Cancer: Expression of Lymphangiogenic Markers Is Associated with Advanced-Stage Disease

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Prognostic Significance of MMP-1 and MMP-3 Functional Promoter Polymorphisms in Colorectal Cancer

Franck Zinzindohoué; Thierry Lecomte; Jean-Marc Ferraz; Anne-Marie Houllier; Paul-Henri Cugnenc; Anne Berger; Hélène Blons; Pierre Laurent-Puig

Abstract

View articletitled, Prognostic Significance of MMP-1 and MMP-3 Functional Promoter Polymorphisms in Colorectal Cancer

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Epidermal Growth Factor Receptor Gene Polymorphisms Predict Pelvic Recurrence in Patients with Rectal Cancer Treated with Chemoradiation

Wu Zhang; David J. Park; Bo Lu; Dong Yun Yang; Michael Gordon; Susan Groshen; Jim Yun; Oliver A. Press; Daniel Vallböhmer; Katrin Rhodes; Heinz-Josef Lenz

Abstract

View articletitled, Epidermal Growth Factor Receptor Gene Polymorphisms Predict Pelvic Recurrence in Patients with Rectal Cancer Treated with Chemoradiation

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Down-Regulation of S100C Is Associated with Bladder Cancer Progression and Poor Survival

Ashfaque Ahmed Memon; Boe Sandahl Sorensen; Peter Meldgaard; Lars Fokdal; Thomas Thykjaer; Ebba Nexo

Abstract

View articletitled, Down-Regulation of S100C Is Associated with Bladder Cancer Progression and Poor Survival

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Gene Copy Number Change Events at Chromosome 20 and Their Association with Recurrence in Gastric Cancer Patients

Sang Hwa Yang; Min Young Seo; Ha Jin Jeong; Hei-Cheul Jeung; Jihye Shin; Sang Chul Kim; Sung Hoon Noh; Hyun Cheol Chung; Sun Young Rha

Abstract

View articletitled, Gene Copy Number Change Events at Chromosome 20 and Their Association with Recurrence in Gastric Cancer Patients

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Classic and Molecular Cytogenetic Analyses Reveal Chromosomal Gains and Losses Correlated with Survival in Head and Neck Cancer Patients

Nádia Aparecida Bérgamo; Luciana Caricati da Silva Veiga; Patricia Pintor dos Reis; Inês Nobuko Nishimoto; José Magrin; Luiz Paulo Kowalski; Jeremy A. Squire; Sílvia Regina Rogatto

Abstract

View articletitled, Classic and Molecular Cytogenetic Analyses Reveal Chromosomal Gains and Losses Correlated with Survival in Head and Neck Cancer Patients

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Subcellular Localization of p27^kip1 Expression Predicts Poor Prognosis in Human Ovarian Cancer

Daniel G. Rosen; Gong Yang; Kathy Qi Cai; Robert C. Bast, Jr.; David M. Gershenson; Elvio G. Silva; Jinsong Liu

Abstract

View articletitled, Subcellular Localization of p27kip1 Expression Predicts Poor Prognosis in Human Ovarian Cancer

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Loss of p16 Protein Defines High-Risk Patients with Gastrointestinal Stromal Tumors: A Tissue Microarray Study

Regine Schneider-Stock; Carsten Boltze; Jerzy Lasota; Brigitte Peters; Chris L. Corless; Petra Ruemmele; Luigi Terracciano; Matthias Pross; Luigi Insabato; Dolores Di Vizio; Igor Iesalnieks; Stefan Dirnhofer; Arndt Hartmann; Michel Heinrich; Markku Miettinen; Albert Roessner; Luigi Tornillo

Abstract

View articletitled, Loss of p16 Protein Defines High-Risk Patients with Gastrointestinal Stromal Tumors: A Tissue Microarray Study

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Gene Expression in Kidney Cancer Is Associated with Cytogenetic Abnormalities, Metastasis Formation, and Patient Survival

Holger Sültmann; Anja von Heydebreck; Wolfgang Huber; Ruprecht Kuner; Andreas Buneβ; Markus Vogt; Bastian Gunawan; Martin Vingron; Laszlo Füzesí; Annemarie Poustka

Abstract

View articletitled, Gene Expression in Kidney Cancer Is Associated with Cytogenetic Abnormalities, Metastasis Formation, and Patient Survival

Supplementary data

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Prognostic Significance of CpG Island Methylator Phenotype and Microsatellite Instability in Gastric Carcinoma

Changhyeok An; In-Seon Choi; James C. Yao; Samidha Worah; Keping Xie; Paul F. Mansfield; Jaffer A. Ajani; Asif Rashid; Stanley R. Hamilton; Tsung-Teh Wu

Abstract

View articletitled, Prognostic Significance of CpG Island Methylator Phenotype and Microsatellite Instability in Gastric Carcinoma

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Cancer Therapy: Clinical

A Phase I and Pharmacokinetic Study of Short Infusions of UCN-01 in Patients with Refractory Solid Tumors

E. Claire Dees; Sharyn D. Baker; Seamus O'Reilly; Michelle A. Rudek; Susan B. Davidson; Cheryl Aylesworth; Kathy Elza-Brown; Michael A. Carducci; Ross C. Donehower

Abstract

View articletitled, A Phase I and Pharmacokinetic Study of Short Infusions of UCN-01 in Patients with Refractory Solid Tumors

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A Phase I and Pharmacokinetic Study of Ecteinascidin-743 (Yondelis) in Children with Refractory Solid Tumors. A Children's Oncology Group Study

Loretta Lau; Jeffery G. Supko; Susan Blaney; Linda Hershon; Nita Seibel; Mark Krailo; Wenchun Qu; David Malkin; Jose Jimeno; Mark Bernstein; Sylvain Baruchel; for the Children's Oncology Group

Abstract

View articletitled, A Phase I and Pharmacokinetic Study of Ecteinascidin-743 (Yondelis) in Children with Refractory Solid Tumors. A Children's Oncology Group Study

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Pharmacodynamic Analysis of Target Inhibition and Endothelial Cell Death in Tumors Treated with the Vascular Endothelial Growth Factor Receptor Antagonists SU5416 or SU6668

Darren W. Davis; Ryan Takamori; Chandrajit P. Raut; Henry Q. Xiong; Roy S. Herbst; Walter M. Stadler; John V. Heymach; George D. Demetri; Asif Rashid; Yu Shen; Sijin Wen; James L. Abbruzzese; David J. McConkey

Abstract

View articletitled, Pharmacodynamic Analysis of Target Inhibition and Endothelial Cell Death in Tumors Treated with the Vascular Endothelial Growth Factor Receptor Antagonists SU5416 or SU6668

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Pemetrexed Combined with Oxaliplatin or Carboplatin as First-Line Treatment in Advanced Non–Small Cell Lung Cancer: A Multicenter, Randomized, Phase II Trial

Giorgio V. Scagliotti; Cornelius Kortsik; Graham G. Dark; Allan Price; Christian Manegold; Rafael Rosell; Mary O'Brien; Patrick M. Peterson; Daniel Castellano; Giovanni Selvaggi; Silvia Novello; Johannes Blatter; Louis Kayitalire; Lucio Crino; Luis Paz-Ares

Abstract

View articletitled, Pemetrexed Combined with Oxaliplatin or Carboplatin as First-Line Treatment in Advanced Non–Small Cell Lung Cancer: A Multicenter, Randomized, Phase II Trial

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Phase I/II Study of the Rituximab-EPOCT Regimen in Combination with Granulocyte Colony-Stimulating Factor in Patients with Relapsed or Refractory Follicular Lymphoma Including Evaluation of Its Cardiotoxicity Using B-Type Natriuretic Peptide and Troponin T Levels

Nozomi Niitsu; Mika Khori; Miyuki Hayama; Koichi Kajiwara; Masaaki Higashihara; Jun-ichi Tamaru

Abstract

View articletitled, Phase I/II Study of the Rituximab-EPOCT Regimen in Combination with Granulocyte Colony-Stimulating Factor in Patients with Relapsed or Refractory Follicular Lymphoma Including Evaluation of Its Cardiotoxicity Using B-Type Natriuretic Peptide and Troponin T Levels

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Phase I and Pharmacokinetic Study of DE-310 in Patients with Advanced Solid Tumors

Otto Soepenberg; Maja J. A. de Jonge; Alex Sparreboom; Peter de Bruin; Ferry A. L. M. Eskens; Gerda de Heus; Jantien Wanders; Peter Cheverton; Murray P. Ducharme; Jaap Verweij

Abstract

View articletitled, Phase I and Pharmacokinetic Study of DE-310 in Patients with Advanced Solid Tumors

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Cancer Therapy: Preclinical

Targeting Cyclooxygenase-2 Reduces Overt Toxicity toward Low-Dose Vinblastine and Extends Survival of Juvenile Mice with Friend Disease

Dave Cervi; Giannoula Klement; Diana Stempak; Sylvain Baruchel; Alane Koki; Yaacov Ben-David

Abstract

View articletitled, Targeting Cyclooxygenase-2 Reduces Overt Toxicity toward Low-Dose Vinblastine and Extends Survival of Juvenile Mice with Friend Disease

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Effect of Tumor Host Microenvironment on Photodynamic Therapy in a Rat Prostate Tumor Model

Bin Chen; Brian W. Pogue; Xiaodong Zhou; Julia A. O'Hara; Nicolas Solban; Eugene Demidenko; P. Jack Hoopes; Tayyaba Hasan

Abstract

View articletitled, Effect of Tumor Host Microenvironment on Photodynamic Therapy in a Rat Prostate Tumor Model

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Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

Sandra Demaria; Noriko Kawashima; Anne Marie Yang; Mary Louise Devitt; James S. Babb; James P. Allison; Silvia C. Formenti

Abstract

View articletitled, Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

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Sequential Immunogene Therapy with Interleukin-12– and Interleukin-15–Engineered Neuroblastoma Cells Cures Metastatic Disease in Syngeneic Mice

Michela Croce; Raffaella Meazza; Anna Maria Orengo; Luana Radic'; Barbara De Giovanni; Claudio Gambini; Barbara Carlini; Vito Pistoia; Lorenzo Mortara; Roberto S. Accolla; Maria Valeria Corrias; Silvano Ferrini

Abstract

View articletitled, Sequential Immunogene Therapy with Interleukin-12– and Interleukin-15–Engineered Neuroblastoma Cells Cures Metastatic Disease in Syngeneic Mice

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Thalidomide Radiosensitizes Tumors through Early Changes in the Tumor Microenvironment

Réginald Ansiaux; Christine Baudelet; Bénédicte F. Jordan; Nelson Beghein; Pierre Sonveaux; Julie De Wever; Philippe Martinive; Vincent Grégoire; Olivier Feron; Bernard Gallez

Abstract

View articletitled, Thalidomide Radiosensitizes Tumors through Early Changes in the Tumor Microenvironment

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Clinical Evaluation of BR96 sFv-PE40 Immunotoxin Therapy in Canine Models of Spontaneously Occurring Invasive Carcinoma

Carolyn J. Henry; Michael S. Buss; Ingegerd Hellström; Karl Erik Hellström; William G. Brewer; Jeffrey N. Bryan; Clay B. Siegall

Abstract

View articletitled, Clinical Evaluation of BR96 sFv-PE40 Immunotoxin Therapy in Canine Models of Spontaneously Occurring Invasive Carcinoma

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Intracellular Localization and Trafficking of Fluorescein-Labeled Cisplatin in Human Ovarian Carcinoma Cells

Roohangiz Safaei; Kuniyuki Katano; Barrett J. Larson; Goli Samimi; Alison K. Holzer; Wiltrud Naerdemann; Mika Tomioka; Murray Goodman; Stephen B. Howell

Abstract

View articletitled, Intracellular Localization and Trafficking of Fluorescein-Labeled Cisplatin in Human Ovarian Carcinoma Cells

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Continuous Delivery of Endogenous Inhibitors from Poly(Lactic-Co-Glycolic Acid) Polymeric Microspheres Inhibits Glioma Tumor Growth

Ofra Benny; Maayan Duvshani-Eshet; Theresa Cargioli; Lorenzo Bello; Andreas Bikfalvi; Rona S. Carroll; Marcelle Machluf

Abstract

View articletitled, Continuous Delivery of Endogenous Inhibitors from Poly(Lactic-Co-Glycolic Acid) Polymeric Microspheres Inhibits Glioma Tumor Growth

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Therapy of Small Subcutaneous B-Lymphoma Xenografts with Antibodies Conjugated to Radionuclides Emitting Low-Energy Electrons

Rosana B. Michel; Adriane V. Rosario; Philip M. Andrews; David M. Goldenberg; M. Jules Mattes

Abstract

View articletitled, Therapy of Small Subcutaneous B-Lymphoma Xenografts with Antibodies Conjugated to Radionuclides Emitting Low-Energy Electrons

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Biodistribution of Yttrium-90–Labeled Anti-CD45 Antibody in a Nonhuman Primate Model

Eneida R. Nemecek; Donald K. Hamlin; Darrell R. Fisher; Kenneth A. Krohn; John M. Pagel; Frederick R. Appelbaum; Oliver W. Press; Dana C. Matthews

Abstract

View articletitled, Biodistribution of Yttrium-90–Labeled Anti-CD45 Antibody in a Nonhuman Primate Model

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The Effects of Cetuximab Alone and in Combination With Radiation and/or Chemotherapy in Lung Cancer

David Raben; Barb Helfrich; Daniel C. Chan; Fortunato Ciardiello; LiMin Zhao; Wilbur Franklin; Anna E. Barón; Chan Zeng; Tim K. Johnson; Paul A. Bunn, Jr

Abstract

View articletitled, The Effects of Cetuximab Alone and in Combination With Radiation and/or Chemotherapy in Lung Cancer

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Adenoviral Transduction of TESTIN Gene into Breast and Uterine Cancer Cell Lines Promotes Apoptosis and Tumor Reduction In vivo

Manuela Sarti; Cinzia Sevignani; George A. Calin; Rami Aqeilan; Masayoshi Shimizu; Francesca Pentimalli; Maria Cristina Picchio; Andrew Godwin; Anne Rosenberg; Alessandra Drusco; Massimo Negrini; Carlo M. Croce

Abstract

View articletitled, Adenoviral Transduction of TESTIN Gene into Breast and Uterine Cancer Cell Lines Promotes Apoptosis and Tumor Reduction In vivo

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Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy

Surinder K. Sharma; R. Barbara Pedley; Jeetendra Bhatia; Geoffrey M. Boxer; Ethaar El-Emir; Uzma Qureshi; Berend Tolner; Helen Lowe; N. Paul Michael; Nigel Minton; Richard H. J. Begent; Kerry A. Chester

Abstract

View articletitled, Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy

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Mathematical Modeling and Optimization of Drug Delivery from Intratumorally Injected Microspheres

Abraham Rami Tzafriri; Elyakum Itzhak Lerner; Moshe Flashner-Barak; Michael Hinchcliffe; Eli Ratner; Hanna Parnas

Abstract

View articletitled, Mathematical Modeling and Optimization of Drug Delivery from Intratumorally Injected Microspheres

Supplementary data

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Effect of the Tumor Vascular-Damaging Agent, ZD6126, on the Radioresponse of U87 Glioblastoma

Phyllis R. Wachsberger; Randy Burd; Nichol Marero; Constantine Daskalakis; Anderson Ryan; Peter McCue; Adam P. Dicker

Abstract

View articletitled, Effect of the Tumor Vascular-Damaging Agent, ZD6126, on the Radioresponse of U87 Glioblastoma

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In vivo Drug-Linker Stability of an Anti-CD30 Dipeptide-Linked Auristatin Immunoconjugate

Russell J. Sanderson; Michelle A. Hering; Stephanie F. James; Michael M.C. Sun; Svetlana O. Doronina; Anthony W. Siadak; Peter D. Senter; Alan F. Wahl

Abstract

View articletitled, In vivo Drug-Linker Stability of an Anti-CD30 Dipeptide-Linked Auristatin Immunoconjugate

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A Third-Generation Bisphosphonate, Minodronic Acid (YM529), Augments the Interferon α/β-Mediated Inhibition of Renal Cell Cancer Cell Growth Both In vitro and In vivo

Takeshi Yuasa; Masaki Nogawa; Shinya Kimura; Asumi Yokota; Kiyoshi Sato; Hidekazu Segawa; Junya Kuroda; Taira Maekawa

Abstract

View articletitled, A Third-Generation Bisphosphonate, Minodronic Acid (YM529), Augments the Interferon α/β-Mediated Inhibition of Renal Cell Cancer Cell Growth Both In vitro and In vivo

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Letter to the Editor

Telomere Length Abnormalities and Human Cancer

Katharina Schroecksnadel; Florian Ueberall; Dietmar Fuchs

Extract

View articletitled, Telomere Length Abnormalities and Human Cancer

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Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer

Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: Conference Summary Statement

Steven E. Come; Aman U. Buzdar; James N. Ingle; Carlos L. Arteaga; Angela M. Brodie; Graham A. Colditz; Stephen R.D. Johnston; Vessela N. Kristensen; Per E. Lønning; Donald P. McDonnell; C. Kent Osborne; Jose Russo; Richard J. Santen; Douglas Yee; Carol S. Hart

Extract

View articletitled, Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: Conference Summary Statement

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Crosstalk between Estrogen Receptor and Growth Factor Receptor Pathways as a Cause for Endocrine Therapy Resistance in Breast Cancer

C. Kent Osborne; Jiang Shou; Suleiman Massarweh; Rachel Schiff

Abstract

View articletitled, Crosstalk between Estrogen Receptor and Growth Factor Receptor Pathways as a Cause for Endocrine Therapy Resistance in Breast Cancer

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The Molecular Pharmacology of Estrogen Receptor Modulators: Implications for the Treatment of Breast Cancer

Donald P. McDonnell

Abstract

View articletitled, The Molecular Pharmacology of Estrogen Receptor Modulators: Implications for the Treatment of Breast Cancer

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Gene Expression Profiling of Breast Cancer in Relation to Estrogen Receptor Status and Estrogen-Metabolizing Enzymes: Clinical Implications

Vessela N. Kristensen; Therese Sørlie; Jurgen Geisler; Anita Langerød; Noriko Yoshimura; Rolf Kåresen; Nobuhiro Harada; P.E. Lønning; Anne-Lise Børresen-Dale

Abstract

View articletitled, Gene Expression Profiling of Breast Cancer in Relation to Estrogen Receptor Status and Estrogen-Metabolizing Enzymes: Clinical Implications

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Therapeutic Observations in MCF-7 Aromatase Xenografts

Angela Brodie; Danijela Jelovac; Luciana Macedo; Gauri Sabnis; Syreeta Tilghman; Olga Goloubeva

Abstract

View articletitled, Therapeutic Observations in MCF-7 Aromatase Xenografts

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Combinations of Endocrine and Biological Agents: Present Status of Therapeutic and Presurgical Investigations

Stephen RD Johnston

Abstract

View articletitled, Combinations of Endocrine and Biological Agents: Present Status of Therapeutic and Presurgical Investigations

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Endocrine Therapy Trials of Aromatase Inhibitors for Breast Cancer in the Adjuvant and Prevention Settings

James N. Ingle

Abstract

View articletitled, Endocrine Therapy Trials of Aromatase Inhibitors for Breast Cancer in the Adjuvant and Prevention Settings

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TAS-108: A Novel Steroidal Antiestrogen

Aman U. Buzdar

Abstract

View articletitled, TAS-108: A Novel Steroidal Antiestrogen

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Estrogen, Estrogen Plus Progestin Therapy, and Risk of Breast Cancer

Graham A. Colditz

Abstract

View articletitled, Estrogen, Estrogen Plus Progestin Therapy, and Risk of Breast Cancer

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Exemestane for Breast Cancer Prevention: A Feasible Strategy?

Per E. Lønning

Abstract

View articletitled, Exemestane for Breast Cancer Prevention: A Feasible Strategy?

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Tamoxifen versus Aromatase Inhibitors for Breast Cancer Prevention

Wei Yue; Ji-Ping Wang; Yuebai Li; Wayne P. Bocchinfuso; Kenneth S. Korach; Prabu D. Devanesan; Eleanor Rogan; Ercole Cavalieri; Richard J. Santen

Abstract

View articletitled, Tamoxifen versus Aromatase Inhibitors for Breast Cancer Prevention

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Breast Differentiation and Its Implication in Cancer Prevention

Jose Russo; Daniel Mailo; Yun-Fu Hu; Gabriela Balogh; Fathima Sheriff; Irma H. Russo

Abstract

View articletitled, Breast Differentiation and Its Implication in Cancer Prevention

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Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression

Rebecca S. Muraoka-Cook; Nancy Dumont; Carlos L. Arteaga

Abstract

View articletitled, Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression

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Insulin-Like Growth Factor-I and Breast Cancer Therapy

Yasir H. Ibrahim; Douglas Yee

Abstract

View articletitled, Insulin-Like Growth Factor-I and Breast Cancer Therapy

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Short-Term Changes in Ki-67 during Neoadjuvant Treatment of Primary Breast Cancer with Anastrozole or Tamoxifen Alone or Combined Correlate with Recurrence-Free Survival

Mitch Dowsett; Ian E. Smith; Steve R. Ebbs; J. Michael Dixon; Anthony Skene; Clive Griffith; Irene Boeddinghaus; Janine Salter; Simone Detre; Margaret Hills; Susan Ashley; Stephen Francis; Geraldine Walsh; on behalf of the IMPACT Trialists

Abstract

View articletitled, Short-Term Changes in Ki-67 during Neoadjuvant Treatment of Primary Breast Cancer with Anastrozole or Tamoxifen Alone or Combined Correlate with Recurrence-Free Survival

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