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Issues

Volume 11, Issue 12
15 June 2005
Issue Cover
All Issues
ISSN 1078-0432
EISSN 1557-3265

Editorial

Translating Research into Clinical Practice: Deliberations from the American Association for Cancer Research
William N. Hait
View articletitled, Translating Research into Clinical Practice: Deliberations from the American Association for Cancer Research
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The Biology Behind

Getting at MYC through RAS
Pavan Bachireddy; Pavan K. Bendapudi; Dean W. Felsher
View articletitled, Getting at MYC through RAS
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Human Cancer Biology

Regulation of Fibroblast Growth Factor-2 Activity by Human Ovarian Cancer Tumor Endothelium
Melissa K. Whitworth; Alison C. Backen; Andrew R. Clamp; Godfrey Wilson; Rhona McVey; Andreas Friedl; Alan C. Rapraeger; Guido David; Alan McGown; Richard J. Slade; John T. Gallagher; Gordon C. Jayson
View articletitled, Regulation of Fibroblast Growth Factor-2 Activity by Human Ovarian Cancer Tumor Endothelium
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Gefitinib-Sensitive Mutations of the Epidermal Growth Factor Receptor Tyrosine Kinase Domain in Chinese Patients with Non–Small Cell Lung Cancer
Xin Lin Mu; Long Yun Li; Xiao Tong Zhang; Men Zhao Wang; Rui E. Feng; Quan Cai Cui; Hai Sheng Zhou; Bing Qing Guo
View articletitled, Gefitinib-Sensitive Mutations of the Epidermal Growth Factor Receptor Tyrosine Kinase Domain in Chinese Patients with Non–Small Cell Lung Cancer
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Elevated Expression of Wnt Antagonists Is a Common Event in Hepatoblastomas
Arend Koch; Andreas Waha; Wolfgang Hartmann; Aksana Hrychyk; Ulrich Schüller; Anke Waha; Keith A. Wharton, Jr; Serge Y. Fuchs; Dietrich von Schweinitz; Torsten Pietsch
View articletitled, Elevated Expression of Wnt Antagonists Is a Common Event in Hepatoblastomas
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Up-Regulation of EphB4 in Mesothelioma and Its Biological Significance
Guangbin Xia; S. Ram Kumar; Rizwan Masood; Michael Koss; Claire Templeman; David Quinn; Sutao Zhu; Ramachandra Reddy; Valery Krasnoperov; Parkash S. Gill
View articletitled, Up-Regulation of EphB4 in Mesothelioma and Its Biological Significance
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Coxsackie and Adenovirus Receptor Promotes Adenocarcinoma Cell Survival and Is Expressionally Activated after Transition from Preneoplastic Precursor Lesions to Invasive Adenocarcinomas
Ansgar Brüning; Elmar Stickeler; Daniel Diederich; Lioba Walz; Hendrik Rohleder; Klaus Friese; Ingo B. Runnebaum
View articletitled, Coxsackie and Adenovirus Receptor Promotes Adenocarcinoma Cell Survival and Is Expressionally Activated after Transition from Preneoplastic Precursor Lesions to Invasive Adenocarcinomas
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Disruption of Cooperation Between Ras and MycN in Human Neuroblastoma Cells Promotes Growth Arrest
Shira Yaari; Jasmine Jacob-Hirsch; Ninette Amariglio; Ronit Haklai; Gideon Rechavi; Yoel Kloog
View articletitled, Disruption of Cooperation Between Ras and MycN in Human Neuroblastoma Cells Promotes Growth Arrest
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Differential Expression of Full-length Telomerase Reverse Transcriptase mRNA and Telomerase Activity between Normal and Malignant Renal Tissues
Yidong Fan; Zhaoxu Liu; Xiaolei Fang; Zheng Ge; Nan Ge; Yong Jia; Peng Sun; Fenglan Lou; Magnus Björkholm; Astrid Gruber; Peter Ekman; Dawei Xu
View articletitled, Differential Expression of Full-length Telomerase Reverse Transcriptase mRNA and Telomerase Activity between Normal and Malignant Renal Tissues
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Imaging, Diagnosis, Prognosis

Stability of Phosphoprotein as a Biological Marker of Tumor Signaling
Amanda F. Baker; Tomislav Dragovich; Nathan T. Ihle; Ryan Williams; Cecilia Fenoglio-Preiser; Garth Powis
View articletitled, Stability of Phosphoprotein as a Biological Marker of Tumor Signaling
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2-[11C]Thymidine Positron Emission Tomography Reproducibility in Humans
Paula Wells; Roger N. Gunn; Colin Steel; Alex S. Ranicar; Frank Brady; Safiye Osman; Terry Jones; Pat Price
View articletitled, 2-[<sup>11</sup>C]Thymidine Positron Emission Tomography Reproducibility in Humans
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Evaluation of the Combined Effect of p53 Codon 72 Polymorphism and Hotspot Mutations in Response to Anticancer Drugs
Faina Vikhanskaya; Mobin M. Siddique; Ming Kei Lee; Massimo Broggini; Kanaga Sabapathy
View articletitled, Evaluation of the Combined Effect of p53 Codon 72 Polymorphism and Hotspot Mutations in Response to Anticancer Drugs
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Aberrant Expression of Novel and Previously Described Cell Membrane Markers in Human Breast Cancer Cell Lines and Tumors
Huayi Huang; Jeff Groth; Khalid Sossey-Alaoui; Lesleyann Hawthorn; Stephanie Beall; Joseph Geradts
View articletitled, Aberrant Expression of Novel and Previously Described Cell Membrane Markers in Human Breast Cancer Cell Lines and Tumors
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Steroid 5α-Reductase Isozymes I and II in Recurrent Prostate Cancer
Mark A. Titus; Christopher W. Gregory; O. Harris Ford, III; Michael J. Schell; Susan J. Maygarden; James L. Mohler
View articletitled, Steroid 5α-Reductase Isozymes I and II in Recurrent Prostate Cancer
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Down-Regulated Xanthine Oxidoreductase Is a Feature of Aggressive Breast Cancer
Nina Linder; Johan Lundin; Jorma Isola; Mikael Lundin; Kari O. Raivio; Heikki Joensuu
View articletitled, Down-Regulated Xanthine Oxidoreductase Is a Feature of Aggressive Breast Cancer
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Effects of Chemotherapy on the Cytogenetic Constitution of Wilms' Tumor
Thorsten Schlomm; Bastian Gunawan; Hans-Jürgen Schulten; Björn Sander; Karthinathan Thangavelu; Norbert Graf; Ivo Leuschner; Rolf-Hermann Ringert; László Füzesi
View articletitled, Effects of Chemotherapy on the Cytogenetic Constitution of Wilms' Tumor
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Low-Molecular Weight Caldesmon as a Potential Serum Marker for Glioma
Ping-Pin Zheng; Wim C. Hop; Peter A.E. Sillevis Smitt; Martin J. van den Bent; Cees J.J. Avezaat; Theodorus M. Luider; Johan M. Kros
View articletitled, Low-Molecular Weight Caldesmon as a Potential Serum Marker for Glioma
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Polysomy 17 in HER-2/neu Status Elaboration in Breast Cancer: Effect on Daily Practice
Yan Ma; Laurence Lespagnard; Virginie Durbecq; Marianne Paesmans; Christine Desmedt; Maria Gomez-Galdon; Isabelle Veys; Fatima Cardoso; Christos Sotiriou; Angelo Di Leo; Martine J. Piccart; Denis Larsimont
View articletitled, Polysomy 17 in HER-2/neu Status Elaboration in Breast Cancer: Effect on Daily Practice
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Methylation Profiling of Archived Non–Small Cell Lung Cancer: A Promising Prognostic System
A. Mazin Safar; Horace Spencer, III; Xiaobo Su; Maureen Coffey; Craig A. Cooney; Luke D. Ratnasinghe; Laura F. Hutchins; Chun-Yang Fan
View articletitled, Methylation Profiling of Archived Non–Small Cell Lung Cancer: A Promising Prognostic System
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Validation of Genomics-Based Prognostic Tests in Malignant Pleural Mesothelioma
Gavin J. Gordon; Graham N. Rockwell; Paul A. Godfrey; Roderick V. Jensen; Jonathan N. Glickman; Beow Y. Yeap; William G. Richards; David J. Sugarbaker; Raphael Bueno
View articletitled, Validation of Genomics-Based Prognostic Tests in Malignant Pleural Mesothelioma
Supplementary data
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Gene Expression Profiling of Progressive Papillary Noninvasive Carcinomas of the Urinary Bladder
Peter J. Wild; Alexander Herr; Christoph Wissmann; Robert Stoehr; Andre Rosenthal; Dirk Zaak; Ronald Simon; Ruth Knuechel; Christian Pilarsky; Arndt Hartmann
View articletitled, Gene Expression Profiling of Progressive Papillary Noninvasive Carcinomas of the Urinary Bladder
Supplementary data
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Cancer Therapy: Clinical

Unexpected Association between Induction of Immunity to the Universal Tumor Antigen CYP1B1 and Response to Next Therapy
John G. Gribben; David P. Ryan; Richard Boyajian; Robert G. Urban; Mary L. Hedley; Kathleen Beach; Patrick Nealon; Ursula Matulonis; Susana Campos; Timothy D. Gilligan; Paul G. Richardson; Blossom Marshall; Donna Neuberg; Lee M. Nadler
View articletitled, Unexpected Association between Induction of Immunity to the Universal Tumor Antigen CYP1B1 and Response to Next Therapy
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Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial
Eli Rosenbaum; Marianna Zahurak; Victoria Sinibaldi; Michael A. Carducci; Roberto Pili; Menachem Laufer; Theodore L. DeWeese; Mario A. Eisenberger
View articletitled, Marimastat in the Treatment of Patients with Biochemically Relapsed Prostate Cancer: A Prospective Randomized, Double-Blind, Phase I/II Trial
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The Cyclin-Dependent Kinase Inhibitor UCN-01 Plus Cisplatin in Advanced Solid Tumors: A California Cancer Consortium Phase I Pharmacokinetic and Molecular Correlative Trial
Primo N. Lara, Jr; Philip C. Mack; Timothy Synold; Paul Frankel; Jeff Longmate; Paul H. Gumerlock; James H. Doroshow; David R. Gandara
View articletitled, The Cyclin-Dependent Kinase Inhibitor UCN-01 Plus Cisplatin in Advanced Solid Tumors: A California Cancer Consortium Phase I Pharmacokinetic and Molecular Correlative Trial
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First Clinical Experience with α-Emitting Radium-223 in the Treatment of Skeletal Metastases
Sten Nilsson; Roy H. Larsen; Sophie D. Fosså; Lise Balteskard; Kari W. Borch; Jan-Erik Westlin; Gro Salberg; Øyvind S. Bruland
View articletitled, First Clinical Experience with α-Emitting Radium-223 in the Treatment of Skeletal Metastases
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Combination of Imatinib Mesylate with Autologous Leukocyte-Derived Heat Shock Protein and Chronic Myelogenous Leukemia
Zihai Li; Yi Qiao; Bei Liu; Elizabeth J. Laska; Priyamvadha Chakravarthi; Judith M. Kulko; Robert D. Bona; Min Fang; Upendra Hegde; Victor Moyo; Susan H. Tannenbaum; Antoine Ménoret; Judy Gaffney; Laura Glynn; Carolyn D. Runowicz; Pramod K. Srivastava
View articletitled, Combination of Imatinib Mesylate with Autologous Leukocyte-Derived Heat Shock Protein and Chronic Myelogenous Leukemia
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Delayed Disease Progression after Allogeneic Cell Vaccination in Hormone-Resistant Prostate Cancer and Correlation with Immunologic Variables
Agnieska Michael; Graham Ball; Nadine Quatan; Fatima Wushishi; Nick Russell; Joe Whelan; Prabir Chakraborty; David Leader; Michael Whelan; Hardev Pandha
View articletitled, Delayed Disease Progression after Allogeneic Cell Vaccination in Hormone-Resistant Prostate Cancer and Correlation with Immunologic Variables
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Cancer Therapy: Preclinical

Targeting the c-Met Pathway Potentiates Glioblastoma Responses to γ-Radiation
Bachchu Lal; Shuli Xia; Roger Abounader; John Laterra
View articletitled, Targeting the c-Met Pathway Potentiates Glioblastoma Responses to γ-Radiation
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In vivo RNA Interference–Mediated Ablation of MDR1 P-Glycoprotein
Andrea Pichler; Noam Zelcer; Julie L. Prior; Annemieke J. Kuil; David Piwnica-Worms
View articletitled, <em>In vivo</em> RNA Interference–Mediated Ablation of <em>MDR1</em> P-Glycoprotein
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In vitro Induction of Myeloid Leukemia–Specific CD4 and CD8 T Cells by CD40 Ligand – Activated B Cells Gene Modified to Express Primary Granule Proteins
Hiroshi Fujiwara; J. Joseph Melenhorst; Frank El Ouriaghli; Sachiko Kajigaya; Matthias Grube; Giuseppe Sconocchia; Katayoun Rezvani; David A. Price; Nancy F. Hensel; Daniel C. Douek; A. John Barrett
View articletitled, <em>In vitro</em> Induction of Myeloid Leukemia–Specific CD4 and CD8 T Cells by CD40 Ligand – Activated B Cells Gene Modified to Express Primary Granule Proteins
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Graft-versus-Leukemia Target Antigens in Chronic Myelogenous Leukemia Are Expressed on Myeloid Progenitor Cells
Catherine J. Wu; Melinda Biernacki; Jeffery L. Kutok; Shelby Rogers; Linyun Chen; Xiao-Feng Yang; Robert J. Soiffer; Jerome Ritz
View articletitled, Graft-versus-Leukemia Target Antigens in Chronic Myelogenous Leukemia Are Expressed on Myeloid Progenitor Cells
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Blockade of Transforming Growth Factor-β Signaling Suppresses Progression of Androgen-Independent Human Prostate Cancer in Nude Mice
Fahao Zhang; Juwon Lee; Shan Lu; Curtis A. Pettaway; Zhongyun Dong
View articletitled, Blockade of Transforming Growth Factor-β Signaling Suppresses Progression of Androgen-Independent Human Prostate Cancer in Nude Mice
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The Antitumor and Antiangiogenic Activity of Vascular Endothelial Growth Factor Receptor Inhibition Is Potentiated by ErbB1 Blockade
Patrizia Sini; Lorenza Wyder; Christian Schnell; Terence O'Reilly; Amanda Littlewood; Ralph Brandt; Nancy E. Hynes; Jeanette Wood
View articletitled, The Antitumor and Antiangiogenic Activity of Vascular Endothelial Growth Factor Receptor Inhibition Is Potentiated by ErbB1 Blockade
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The Requirement of Multimodal Therapy (Vaccine, Local Tumor Radiation, and Reduction of Suppressor Cells) to Eliminate Established Tumors
Chie Kudo-Saito; Jeffrey Schlom; Kevin Camphausen; C. Norman Coleman; James W. Hodge
View articletitled, The Requirement of Multimodal Therapy (Vaccine, Local Tumor Radiation, and Reduction of Suppressor Cells) to Eliminate Established Tumors
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Recognition of Six-Transmembrane Epithelial Antigen of the Prostate–Expressing Tumor Cells by Peptide Antigen–Induced Cytotoxic T Lymphocytes
David A. Rodeberg; Rebecca A. Nuss; Sherine F. Elsawa; Esteban Celis
View articletitled, Recognition of Six-Transmembrane Epithelial Antigen of the Prostate–Expressing Tumor Cells by Peptide Antigen–Induced Cytotoxic T Lymphocytes
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Oncolytic Viral Therapy for Cervical and Ovarian Cancer Cells by Sindbis Virus AR339 Strain
Youichi Unno; Yuji Shino; Fukuo Kondo; Natsuhiko Igarashi; Gang Wang; Ryuhi Shimura; Taketo Yamaguchi; Takehide Asano; Hiromitsu Saisho; Souei Sekiya; Hiroshi Shirasawa
View articletitled, Oncolytic Viral Therapy for Cervical and Ovarian Cancer Cells by Sindbis Virus AR339 Strain
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Low Levels of Her2/neu Expressed by Ewing's Family Tumor Cell Lines Can Redirect Cytokine-Induced Killer Cells
Michael R. Verneris; Arash Arshi; Matthias Edinger; Martin Kornacker; Yaso Natkunam; Mobin Karami; Yu-an Cao; Neyssa Marina; Christopher H. Contag; Robert S. Negrin
View articletitled, Low Levels of Her2/neu Expressed by Ewing's Family Tumor Cell Lines Can Redirect Cytokine-Induced Killer Cells
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Enhancement of In vitro and In vivo Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine
Hideaki Dote; David Cerna; William E. Burgan; Donna J. Carter; Michael A. Cerra; Melinda G. Hollingshead; Kevin Camphausen; Philip J. Tofilon
View articletitled, Enhancement of <em>In vitro</em> and <em>In vivo</em> Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine
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Activation of p53-Dependent Apoptosis by Acute Ablation of Glycogen Synthase Kinase-3β in Colorectal Cancer Cells
Jagadish C. Ghosh; Dario C. Altieri
View articletitled, Activation of p53-Dependent Apoptosis by Acute Ablation of Glycogen Synthase Kinase-3β in Colorectal Cancer Cells
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The Farnesyltransferase Inhibitor L744832 Potentiates UCN-01–Induced Apoptosis in Human Multiple Myeloma Cells
Xin-Yan Pei; Yun Dai; Mohamed Rahmani; Weiqun Li; Paul Dent; Steven Grant
View articletitled, The Farnesyltransferase Inhibitor L744832 Potentiates UCN-01–Induced Apoptosis in Human Multiple Myeloma Cells
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Systemic Treatment with Tetra-O-Methyl Nordihydroguaiaretic Acid Suppresses the Growth of Human Xenograft Tumors
Richard Park; Chih-Chuan Chang; Yu-Chuan Liang; Yousun Chung; Ryan A. Henry; Elaine Lin; David E. Mold; Ru Chih C. Huang
View articletitled, Systemic Treatment with Tetra-<em>O</em>-Methyl Nordihydroguaiaretic Acid Suppresses the Growth of Human Xenograft Tumors
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Cancer Prevention

The Transforming Growth Factor-β Family Members Bone Morphogenetic Protein-2 and Macrophage Inhibitory Cytokine-1 as Mediators of the Antiangiogenic Activity of N-(4-Hydroxyphenyl)Retinamide
Nicoletta Ferrari; Ulrich Pfeffer; Raffaella Dell'Eva; Claudia Ambrosini; Douglas M. Noonan; Adriana Albini
View articletitled, The Transforming Growth Factor-β Family Members Bone Morphogenetic Protein-2 and Macrophage Inhibitory Cytokine-1 as Mediators of the Antiangiogenic Activity of <em>N</em>-(4-Hydroxyphenyl)Retinamide
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Genetic Polymorphisms of Selected DNA Repair Genes, Estrogen and Progesterone Receptor Status, and Breast Cancer Risk
Kyoung-Mu Lee; Ji-Yeob Choi; Changwon Kang; Changsoo Paul Kang; Sue Kyung Park; Hyunmi Cho; Dae-Yeon Cho; Keun-Young Yoo; Dong-Young Noh; Sei-Hyun Ahn; Chung-Gyu Park; Qingyi Wei; Daehee Kang
View articletitled, Genetic Polymorphisms of Selected DNA Repair Genes, Estrogen and Progesterone Receptor Status, and Breast Cancer Risk
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Effects of Dosing Condition on the Oral Bioavailability of Green Tea Catechins after Single-Dose Administration of Polyphenon E in Healthy Individuals
H-H. Sherry Chow; Iman A. Hakim; Donna R. Vining; James A. Crowell; James Ranger-Moore; Wade M. Chew; Catherine A. Celaya; Steven R. Rodney; Yukihiko Hara; David S. Alberts
View articletitled, Effects of Dosing Condition on the Oral Bioavailability of Green Tea Catechins after Single-Dose Administration of Polyphenon E in Healthy Individuals
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Letters to the Editor

Researchers Should Have Respect for the Originator of the Cell Lines
Yutaka Shimada
View articletitled, Researchers Should Have Respect for the Originator of the Cell Lines
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Correction

Correction: Article on Overexpression of Aurora-A and Malignant Development of Human Esophageal Squamous Cell Carcinoma
View articletitled, Correction: Article on Overexpression of Aurora-A and Malignant Development of Human Esophageal Squamous Cell Carcinoma
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  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

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