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Human Cancer Biology
In vivo Target Modulation and Biological Activity of CHIR-258, a Multitargeted Growth Factor Receptor Kinase Inhibitor, in Colon Cancer Models
Sang Hoon Lee; Daniel Lopes de Menezes; Jayesh Vora; Alex Harris; Helen Ye; Lara Nordahl; Evelyn Garrett; Emil Samara; Sharon Lea Aukerman; Arnold B. Gelb; Carla Heise
Association of Visceral Fat Accumulation and Plasma Adiponectin with Colorectal Adenoma: Evidence for Participation of Insulin Resistance
Sayaka Otake; Hiroaki Takeda; Yasukuni Suzuki; Tadahisa Fukui; Shinichiro Watanabe; Katsuyoshi Ishihama; Takafumi Saito; Hitoshi Togashi; Tadashi Nakamura; Yuji Matsuzawa; Sumio Kawata
Vascular Endothelial Growth Factor Polymorphisms in Relation to Breast Cancer Development and Prognosis
Qianren Jin; Kari Hemminki; Kerstin Enquist; Per Lenner; Ewa Grzybowska; Rüdiger Klaes; Roger Henriksson; Bowang Chen; Jolanta Pamula; Wioletta Pekala; Helena Zientek; Jadwiga Rogozinska-Szczepka; Beata Utracka-Hutka; Göran Hallmans; Asta Försti
Genetic Abnormalities and Patterns of Antigenic Expression in Multiple Myeloma
Gema Mateo; Mariana Castellanos; Ana Rasillo; Norma C. Gutiérrez; Ma. Angeles Montalbán; Ma. Luisa Martín; Jesús Ma. Hernández; Ma. Consuelo López-Berges; Laura Montejano; Joan Bladé; Ma. Victoria Mateos; Anna Sureda; Javier de la Rubia; Joaquín Díaz-Mediavilla; Atanasio Pandiella; Juan José Lahuerta; Alberto Orfao; Jesús F. San Miguel
Imaging, Diagnosis, Prognosis
Analysis of KIT Mutations in Sporadic and Familial Gastrointestinal Stromal Tumors: Therapeutic Implications through Protein Modeling
Chi Tarn; Erin Merkel; Adrian A. Canutescu; Wei Shen; Yuliya Skorobogatko; Martin J. Heslin; Burton Eisenberg; Ruth Birbe; Arthur Patchefsky; Roland Dunbrack; J. Pablo Arnoletti; Margaret von Mehren; Andrew K. Godwin
Patterns of Gene Expression That Characterize Long-term Survival in Advanced Stage Serous Ovarian Cancers
Andrew Berchuck; Edwin S. Iversen; Johnathan M. Lancaster; Jennifer Pittman; Jingqin Luo; Paula Lee; Susan Murphy; Holly K. Dressman; Phillip G. Febbo; Mike West; Joseph R. Nevins; Jeffrey R. Marks
Evaluation of a Panel of Tumor Markers for Molecular Detection of Circulating Cancer Cells in Women with Suspected Breast Cancer
Monica M. Reinholz; Andrea Nibbe; Leslie M. Jonart; Kathleen Kitzmann; Vera J. Suman; James N. Ingle; Raymond Houghton; Barbara Zehentner; Patrick C. Roche; Wilma L. Lingle
Mutation in the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor Is a Predictive and Prognostic Factor for Gefitinib Treatment in Patients with Non–Small Cell Lung Cancer
Teh-Ying Chou; Chao-Hua Chiu; Ling-Hui Li; Chun-Yen Hsiao; Chin-Yuan Tzen; Kuo-Ting Chang; Yuh-Min Chen; Reury-Perng Perng; Shih-Feng Tsai; Chun-Ming Tsai
Prognostic Role of Thymidylate Synthase Polymorphisms in Gastric Cancer Patients Treated with Surgery and Adjuvant Chemotherapy
Kazuyuki Kawakami; Francesco Graziano; Go Watanabe; Annamaria Ruzzo; Daniele Santini; Vincenzo Catalano; Renato Bisonni; Federica Arduini; Italo Bearzi; Stefano Cascinu; Pietro Muretto; Giuseppe Perrone; Carla Rabitti; Lucio Giustini; Giuseppe Tonini; Francesca Pizzagalli; Mauro Magnani
Cyclooxygenase-2 Overexpression Is Associated with a Poor Outcome in Resected Ampullary Cancer Patients
Daniele Santini; Bruno Vincenzi; Giuseppe Tonini; Susanna Scarpa; Fortunata Vasaturo; Carolina Malacrino; Fabio Vecchio; Domenico Borzomati; Sergio Valeri; Roberto Coppola; Paolo Magistrelli; Gennaro Nuzzo; Aurelio Picciocchi
Cancer Therapy: Clinical
Phase I and Pharmacokinetic Study of the Dolastatin 10 Analogue TZT-1027, Given on Days 1 and 8 of a 3-Week Cycle in Patients with Advanced Solid Tumors
Maja J.A. de Jonge; Ate van der Gaast; André S.T. Planting; Leny van Doorn; Aletta Lems; Inge Boot; Jantien Wanders; Masahiko Satomi; Jaap Verweij
A Phase I Clinical Trial of the Sequential Combination of Irinotecan Followed by Flavopiridol
Manish A. Shah; Jeremy Kortmansky; Monica Motwani; Marija Drobnjak; Mithat Gonen; Sandy Yi; Amanda Weyerbacher; Carlos Cordon-Cardo; Robert Lefkowitz; Baruch Brenner; Eileen O'Reilly; Leonard Saltz; William Tong; David P. Kelsen; Gary K. Schwartz
A Phase II, Pharmacokinetic, and Biological Correlative Study of Oblimersen Sodium and Docetaxel in Patients with Hormone-Refractory Prostate Cancer
Anthony W. Tolcher; Kim Chi; John Kuhn; Martin Gleave; Amita Patnaik; Chris Takimoto; Garry Schwartz; Ian Thompson; Kristin Berg; Susan D'Aloisio; Nevin Murray; Stanley R. Frankel; Elzbieta Izbicka; Eric Rowinsky
Cancer Therapy: Preclinical
Plasma Pharmacokinetics, Oral Bioavailability, and Interspecies Scaling of the DNA Methyltransferase Inhibitor, Zebularine
Julianne L. Holleran; Robert A. Parise; Erin Joseph; Julie L. Eiseman; Joseph M. Covey; Elizabeth R. Glaze; Alexander V. Lyubimov; Ya-Fei Chen; David Z. D'Argenio; Merrill J. Egorin
A Neutralizing Anti–Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo
Naoki Shimada; Toshihiko Ishii; Teruyoshi Imada; Katsumi Takaba; Yuka Sasaki; Kumiko Maruyama-Takahashi; Yoshimi Maekawa-Tokuda; Hideaki Kusaka; Shiro Akinaga; Akira Tanaka; Kenya Shitara
Frequent Immune Responses to a Cancer/Testis Antigen, CAGE, in Patients with Microsatellite instability–Positive Endometrial Cancer
Takashi Iwata; Tomonobu Fujita; Nobumaru Hirao; Yuriko Matsuzaki; Tsutomu Okada; Hiroshi Mochimaru; Nobuyuki Susumu; Eri Matsumoto; Kokichi Sugano; Naohide Yamashita; Shiro Nozawa; Yutaka Kawakami
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