Skip to Main Content

Advertisement

Umbrella Alt Text
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 10, Issue 20
15 October 2004
Issue Cover
All Issues
ISSN 1078-0432
EISSN 1557-3265

Perspective

Evaluating the Efficiency of Targeted Designs for Randomized Clinical Trials
Richard Simon; Aboubakar Maitournam
View article
PDF

Featured Articles

Clinical Trials
A Phase II Trial of Neoadjuvant Docetaxel and Capecitabine for Locally Advanced Breast Cancer
Peter F. Lebowitz; Jennifer Eng-Wong; Sandra M. Swain; Arlene Berman; Maria J. Merino; Catherine K. Chow; David Venzon; Farah Zia; David Danforth; Edison Liu; JoAnne Zujewski
View article
PDF
Molecular Oncology, Markers, Clinical Correlates
Clinical and Biomarker Correlates of Androgen-Independent, Locally Aggressive Prostate Cancer with Limited Metastatic Potential
Vasily J. Assikis; Kim-Anh Do; Sijin Wen; Xuemei Wang; Jeong Hee Cho-Vega; Shawn Brisbay; Remigio Lopez; Christopher J. Logothetis; Patricia Troncoso; Christos N. Papandreou; Timothy J. McDonnell
View article
PDF
Activation of the Akt/Mammalian Target of Rapamycin/4E-BP1 Pathway by ErbB2 Overexpression Predicts Tumor Progression in Breast Cancers
Xiaoyan Zhou; Ming Tan; Valerie Stone Hawthorne; Kristine S. Klos; Keng-Hsueh Lan; Ying Yang; Wentao Yang; Terry L. Smith; Daren Shi; Dihua Yu
View article
PDF
Molecular Profiling of Inflammatory Breast Cancer: Identification of a Poor-Prognosis Gene Expression Signature
Ivan Bièche; Florence Lerebours; Sengül Tozlu; Marc Espie; Michel Marty; Rosette Lidereau
View article
Supplementary data
PDF
Variability in the Degree of Expression of Phosphorylated IκBα in Chronic Lymphocytic Leukemia Cases With Nodal Involvement
Antonia Rodríguez; Nerea Martínez; Francisca I. Camacho; Elena Ruíz-Ballesteros; Patrocinio Algara; Juan-Fernando García; Javier Menárguez; Tomás Alvaro; Manuel F. Fresno; Fernando Solano; Manuela Mollejo; Carmen Martin; Miguel A. Piris
View article
PDF
Experimental Therapeutics, Preclinical Pharmacology
Components of the Cell Death Machine and Drug Sensitivity of the National Cancer Institute Cell Line Panel
Phyllis A. Svingen; David Loegering; Joe Rodriquez; Xue Wei Meng; Peter W. Mesner, Jr.; Susan Holbeck; Anne Monks; Stan Krajewski; Dominic A. Scudiero; Edward A. Sausville; John C. Reed; Yuri A. Lazebnik; Scott H. Kaufmann
View article
PDF
Induction of Thyroid Cancer Cell Apoptosis by a Novel Nuclear Factor κB Inhibitor, Dehydroxymethylepoxyquinomicin
Dmitriy V. Starenki; Hiroyuki Namba; Vladimir A. Saenko; Akira Ohtsuru; Shigeto Maeda; Kazuo Umezawa; Shunichi Yamashita
View article
PDF

Regular Articles

Clinical Trials
A Phase I and Pharmacodynamic Study of Fludarabine, Carboplatin, and Topotecan in Patients With Relapsed, Refractory, or High-Risk Acute Leukemia
Brenda W. Cooper; Gareth J. Veal; Tomas Radivoyevitch; Michael J. Tilby; Howard J. Meyerson; Hillard M. Lazarus; Omer N. Koc; Richard J. Creger; Graham Pearson; Geoff M. Nowell; David Gosky; Stephen T. Ingalls; Charles L. Hoppel; Stanton L. Gerson
View article
PDF
Effects of α1-Acid Glycoprotein on the Clinical Pharmacokinetics of 7-Hydroxystaurosporine
Alex Sparreboom; Huachen Chen; Milin R. Acharya; Adrian M. Senderowicz; Richard A. Messmann; Takashi Kuwabara; David J. Venzon; Anthony J. Murgo; Donna Headlee; Edward A. Sausville; William D. Figg
View article
PDF
Phase I Clinical Trial of Oral Curcumin: Biomarkers of Systemic Activity and Compliance
Ricky A. Sharma; Stephanie A. Euden; Sharon L. Platton; Darren N. Cooke; Aisha Shafayat; Heather R. Hewitt; Timothy H. Marczylo; Bruno Morgan; David Hemingway; Simon M. Plummer; Munir Pirmohamed; Andreas J. Gescher; William P. Steward
View article
PDF
Effects of Recombinant Erythropoietin in Palliative Treatment of Unselected Cancer Patients
Elisabet Lindholm; Peter Daneryd; Ulla Körner; Anders Hyltander; Marita Fouladiun; Kent Lundholm
View article
PDF

Research Articles

Molecular Oncology, Markers, Clinical Correlates
Phospho-Akt Overexpression in Non–Small Cell Lung Cancer Confers Significant Stage-Independent Survival Disadvantage
Odile David; James Jett; Helena LeBeau; Grace Dy; Janet Hughes; Mitchell Friedman; Arnold R. Brody
View article
PDF
Modulation of Pulmonary Leukotriene B4 Production by Cyclooxygenase-2 Inhibitors and Lipopolysaccharide
Jenny T. Mao; I-Hsien Tsu; Steven M. Dubinett; Bradley Adams; Theodore Sarafian; Felicita Baratelli; Michael D. Roth; Kenneth J. Serio
View article
PDF
Induction of Endothelial Nitric Oxide Synthase Expression by Melanoma Sensitizes Endothelial Cells to Tumor Necrosis Factor-Driven Cytotoxicity
Simone Mocellin; Maurizio Provenzano; Carlo Riccardo Rossi; Pierluigi Pilati; Romano Scalerta; Mario Lise; Donato Nitti
View article
PDF
Proteomic Analysis of Human Acute Leukemia Cells: Insight into Their Classification
Jiu-Wei Cui; Jie Wang; Kun He; Bao-Feng Jin; Hong-Xia Wang; Wei Li; Li-Hua Kang; Mei-Ru Hu; Hui-Yan Li; Ming Yu; Bei-fen Shen; Guan-Jun Wang; Xue-Min Zhang
View article
PDF
Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases
W. Jeffrey Allard; Jeri Matera; M. Craig Miller; Madeline Repollet; Mark C. Connelly; Chandra Rao; Arjan G. J. Tibbe; Jonathan W. Uhr; Leon W. M. M. Terstappen
View article
Supplementary data
PDF
Expression of ΔNp73 Predicts Poor Prognosis in Lung Cancer
Hidetaka Uramoto; Kenji Sugio; Tsunehiro Oyama; Shoji Nakata; Kenji Ono; Masaru Morita; Keiko Funa; Kosei Yasumoto
View article
PDF
Is a Lymph Node Detected by the Dye-Guided Method a True Sentinel Node in Gastric Cancer?
Hirohisa Osaka; Masakazu Yashiro; Tetsuji Sawada; Kei Katsuragi; Kosei Hirakawa
View article
PDF
Lymphatic Vessel Density and Vascular Endothelial Growth Factor-C Expression Correlate with Malignant Behavior in Human Pancreatic Endocrine Tumors
Laura Rubbia-Brandt; Benoit Terris; Emile Giostra; Bertrand Dousset; Philippe Morel; Michael S. Pepper
View article
PDF
Effect of Human Papillomavirus-16 Infection on CD8+ T-Cell Recognition of a Wild-Type Sequence p53264–272 Peptide in Patients with Squamous Cell Carcinoma of the Head and Neck
Nicky Sirianni; Patrick K. Ha; Mattias Oelke; Joseph Califano; William Gooding; William Westra; Theresa L. Whiteside; Wayne M. Koch; Jonathan P. Schneck; Albert DeLeo; Robert L. Ferris
View article
PDF
Concomitant Overexpression of Cyclooxygenase-2 in HER-2–Positive on Smad4-Reduced Human Gastric Carcinomas Is Associated with a Poor Patient Outcome
Hirokazu Okano; Hisashi Shinohara; Akiko Miyamoto; Kyoichi Takaori; Nobuhiko Tanigawa
View article
PDF
The Spontaneous CD8+ T-Cell Response to HLA-A2-Restricted NY-ESO-1b Peptide in Hepatocellular Carcinoma Patients
Xiao-Ying Shang; Hong-Song Chen; Hua-Gang Zhang; Xue-Wen Pang; Huan Qiao; Ji-Run Peng; Li-Ling Qin; Ran Fei; Ming-Hui Mei; Xi-Sheng Leng; Sacha Gnjatic; Gerd Ritter; Andrew J. G. Simpson; Lloyd J. Old; Wei-Feng Chen
View article
PDF
The Absence of Human Equilibrative Nucleoside Transporter 1 Is Associated with Reduced Survival in Patients With Gemcitabine-Treated Pancreas Adenocarcinoma
Jennifer Spratlin; Randeep Sangha; Darryl Glubrecht; Laith Dabbagh; James D. Young; Charles Dumontet; Carol Cass; Raymond Lai; John R. Mackey
View article
PDF
HDAC6 Expression Is Correlated with Better Survival in Breast Cancer
Zhenhuan Zhang; Hiroko Yamashita; Tatsuya Toyama; Hiroshi Sugiura; Yoko Omoto; Yoshiaki Ando; Keiko Mita; Maho Hamaguchi; Shin-ichi Hayashi; Hirotaka Iwase
View article
PDF
Rat Sodium Iodide Symporter for Radioiodide Therapy of Cancer
Elena Mitrofanova; Robert Unfer; Nick Vahanian; Wayne Daniels; Erica Roberson; Tatiana Seregina; Prem Seth; Charles Link, Jr.
View article
PDF
Experimental Therapeutics, Preclinical Pharmacology
Monitoring the Response of Orthotopic Bladder Tumors to Granulocyte Macrophage Colony-Stimulating Factor Therapy Using the Prostate-Specific Antigen Gene as a Reporter
Qinghui Wu; Kesavan Esuvaranathan; Ratha Mahendran
View article
PDF
Treatment of Neuroblastoma Meningeal Carcinomatosis with Intrathecal Application of α-Emitting Atomic Nanogenerators Targeting Disialo-Ganglioside GD2
Matthias Miederer; Michael R. McDevitt; Paul Borchardt; Ira Bergman; Kim Kramer; Nai-Kong V. Cheung; David A. Scheinberg
View article
PDF
Effect of Rapamycin Alone and in Combination with Antiangiogenesis Therapy in an Orthotopic Model of Human Pancreatic Cancer
Susann Stephan; Kaustubh Datta; Enfeng Wang; Jinping Li; Rolf A. Brekken; Sareh Parangi; Philip E. Thorpe; Debabrata Mukhopadhyay
View article
PDF
Fibrinogen-Coated Droplets of Olive Oil for Delivery of Docetaxel to a Fibrin(ogen)-Rich Ascites Form of a Murine Mammary Tumor
Charity M. Einhaus; Andrew C. Retzinger; Andre O. Perrotta; Michael D. Dentler; Abhijeet S. Jakate; Pankaj B. Desai; Gregory S. Retzinger
View article
PDF
The In vitro and In vivo Effects of Re-Expressing Methylated von Hippel-Lindau Tumor Suppressor Gene in Clear Cell Renal Carcinoma with 5-Aza-2′-deoxycytidine
Wade G. Alleman; Ray L. Tabios; Gadisetti V. R. Chandramouli; Olga N. Aprelikova; Carlos Torres-Cabala; Arnulfo Mendoza; Craig Rodgers; Nikolai A. Sopko; W. Marston Linehan; James R. Vasselli
View article
PDF
Troglitazone Acts on Cellular pH and DNA Synthesis through a Peroxisome Proliferator-Activated Receptor γ-Independent Mechanism in Breast Cancer-Derived Cell Lines
Francesco Turturro; Ellen Friday; Rocky Fowler; Diya Surie; Tomas Welbourne
View article
PDF
Targeting Mammalian Target of Rapamycin Synergistically Enhances Chemotherapy-Induced Cytotoxicity in Breast Cancer Cells
Wallace H. Mondesire; Weiguo Jian; Haixia Zhang; Joe Ensor; Mien-Chie Hung; Gordon B. Mills; Funda Meric-Bernstam
View article
PDF
Heteroclitic CD33 Peptide With Enhanced Anti-Acute Myeloid Leukemic Immunogenicity
Jooeun Bae; Jeffrey A. Martinson; Hans G. Klingemann
View article
PDF
Recognition of Adult T-Cell Leukemia/Lymphoma Cells by CD4+ Helper T Lymphocytes Specific for Human T-Cell Leukemia Virus Type I Envelope Protein
Hiroya Kobayashi; Toshihiro Nagato; Mitsuru Yanai; Kensuke Oikawa; Keisuke Sato; Shoji Kimura; Masatoshi Tateno; Ryusuke Omiya; Esteban Celis
View article
PDF
Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate
Kevin J. Hamblett; Peter D. Senter; Dana F. Chace; Michael M. C. Sun; Joel Lenox; Charles G. Cerveny; Kim M. Kissler; Starr X. Bernhardt; Anastasia K. Kopcha; Roger F. Zabinski; Damon L. Meyer; Joseph A. Francisco
View article
PDF
HMMC-1: A Humanized Monoclonal Antibody With Therapeutic Potential Against Müllerian Duct-Related Carcinomas
Shiro Nozawa; Daisuke Aoki; Katsumi Tsukazaki; Nobuyuki Susumu; Motoko Sakayori; Nao Suzuki; Atsushi Suzuki; Rie Wakita; Makio Mukai; Yuko Egami; Kyoko Kojima-Aikawa; Isao Ishida; Frederic Belot; Ole Hindsgaul; Minoru Fukuda; Michiko N. Fukuda
View article
PDF
Abrogation of Head and Neck Squamous Cell Carcinoma Growth by Epidermal Growth Factor Receptor Ligand Fused to Pseudomonas Exotoxin Transforming Growth Factor α-PE38
Sufi M. Thomas; Qing Zeng; Michael W. Epperly; William E. Gooding; Ira Pastan; Qing Cheng Wang; Joel Greenberger; Jennifer Rubin Grandis
View article
PDF
Bioactive Suture: A Novel Immunotherapy for Head and Neck Cancer
Terry Y. Shibuya; Sanghun Kim; Kevin Nguyen; Johnny Do; Christine E. McLaren; Kuo-Tung Li; Wen-Pin Chen; Parag Parikh; Ashish Wadhwa; Xiaolin Zi; Vincent Y. Chen; Hau-Sin Wong; William B. Armstrong; George H. Yoo
View article
PDF
Aberrant Methylation of DPYD Promoter, DPYD Expression, and Cellular Sensitivity to 5-Fluorouracil in Cancer Cells
Takuya Noguchi; Keiji Tanimoto; Tatsushi Shimokuni; Kei Ukon; Hiroaki Tsujimoto; Masakazu Fukushima; Tsuyoshi Noguchi; Katsunobu Kawahara; Keiko Hiyama; Masahiko Nishiyama
View article
PDF

Advertisement

  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

AACR Journals

 

 

  • Copyright © 2022 by the American Association for Cancer Research.
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept