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Clinical Trials
Epratuzumab, a Humanized Anti-CD22 Antibody, in Aggressive Non-Hodgkin’s Lymphoma: Phase I/II Clinical Trial Results
John P. Leonard; Morton Coleman; Jamie C. Ketas; Amy Chadburn; Richard Furman; Michael W. Schuster; Eric J. Feldman; Michelle Ashe; Stephen J. Schuster; William A. Wegener; Hans J. Hansen; Heather Ziccardi; Michael Eschenberg; Urte Gayko; Scott Z. Fields; Alessandra Cesano; David M. Goldenberg
Molecular Oncology, Markers, Clinical Correlates
Nonrandom Distribution of Aberrant Promoter Methylation of Cancer-Related Genes in Sporadic Breast Tumors
Paola Parrella; Maria Luana Poeta; Antonietta Pia Gallo; Maria Prencipe; Marina Scintu; Adolfo Apicella; Raffaele Rossiello; Giuseppina Liguoro; Davide Seripa; Carolina Gravina; Carla Rabitti; Monica Rinaldi; Theresa Nicol; Stefania Tommasi; Angelo Paradiso; Francesco Schittulli; Vittorio Altomare; Vito Michele Fazio
Overexpression of Collagen XVIII Is Associated with Poor Outcome and Elevated Levels of Circulating Serum Endostatin in Non–Small Cell Lung Cancer
Toshihiko Iizasa; Hao Chang; Makoto Suzuki; Mizuto Otsuji; Sana Yokoi; Masako Chiyo; Shinichiro Motohashi; Kazuhiro Yasufuku; Yasuo Sekine; Akira Iyoda; Kiyoshi Shibuya; Kenzo Hiroshima; Takehiko Fujisawa
Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma
Torsten O. Nielsen; Forrest D. Hsu; Kristin Jensen; Maggie Cheang; Gamze Karaca; Zhiyuan Hu; Tina Hernandez-Boussard; Chad Livasy; Dave Cowan; Lynn Dressler; Lars A. Akslen; Joseph Ragaz; Allen M. Gown; C. Blake Gilks; Matt van de Rijn; Charles M. Perou
Experimental Therapeutics, Preclinical Pharmacology
Effects of the Antiestrogen Tamoxifen and the Aromatase Inhibitor Letrozole on Serum Hormones and Bone Characteristics in a Preclinical Tumor Model for Breast Cancer
Nomelí P. Núñez; Danijela Jelovac; Luciana Macedo; David Berrigan; Susan N. Perkins; Stephen D. Hursting; J. Carl Barrett; Angela Brodie
Regular Articles
Clinical Trials
Boosting T Cell-Mediated Immunity to Tyrosinase by Vaccinia Virus-Transduced, CD34+-Derived Dendritic Cell Vaccination: A Phase I Trial in Metastatic Melanoma
Massimo Di Nicola; Carmelo Carlo-Stella; Roberta Mortarini; Paola Baldassari; Anna Guidetti; Gian Francesco Gallino; Michele Del Vecchio; Fernando Ravagnani; Michele Magni; Paul Chaplin; Natale Cascinelli; Giorgio Parmiani; Alessandro M. Gianni; Andrea Anichini
Vaccination with Ep-CAM Protein or Anti-Idiotypic Antibody Induces Th1-Biased Response against MHC Class I- and II-Restricted Ep-CAM Epitopes in Colorectal Carcinoma Patients
Szilvia Mosolits; Katja Markovic; Jan-Erik Frödin; Lena Virving; Carl G. M. Magnusson; Michael Steinitz; Jan Fagerberg; Håkan Mellstedt
Breast Cancer Chemoprevention Phase I Evaluation of Biomarker Modulation by Arzoxifene, a Third Generation Selective Estrogen Receptor Modulator
Carol J. Fabian; Bruce F. Kimler; Julie Anderson; Ossama W. Tawfik; Matthew S. Mayo; William E. Burak, Jr.; Joyce A. O’Shaughnessy; Kathy S. Albain; David M. Hyams; G. Thomas Budd; Patricia A. Ganz; Edward R. Sauter; Samuel W. Beenken; William E. Grizzle; John P. Fruehauf; Dora W. Arneson; James W. Bacus; Michael D. Lagios; Karen A. Johnson; Doris Browne
Phase I Study of Tirapazamine Plus Cisplatin/Etoposide and Concurrent Thoracic Radiotherapy in Limited-Stage Small Cell Lung Cancer (S0004): A Southwest Oncology Group Study
Quynh-Thu Le; Jason McCoy; Stephen Williamson; Janice Ryu; Laurie E. Gaspar; Martin J. Edelman; Shaker R. Dakhil; Stanley D. Sides; John J. Crowley; David R. Gandara
A Phase I and Pharmacokinetic Study of TAS-108 in Postmenopausal Female Patients with Locally Advanced, Locally Recurrent Inoperable, or Progressive Metastatic Breast Cancer
L. Johnetta Blakely; Aman Buzdar; Hsiu-Yin Chang; Debra Frye; Richard Theriault; Vicente Valero; Edgardo Rivera; Daniel Booser; Jun Kuritani; Masuhiro Tsuda
Phase II Clinical Trial of Interleukin-12 in Patients with Relapsed and Refractory Non-Hodgkin’s Lymphoma and Hodgkin’s Disease
Anas Younes; Barbara Pro; Michael J. Robertson; Ian W. Flinn; Jorge E. Romaguera; Fredrick Hagemeister; Nam H. Dang; Paolo Fiumara; Evelyne M. Loyer; Fernando F. Cabanillas; Peter W. McLaughlin; Maria Alma Rodriguez; Felipe Samaniego
Phase II Study of Pemetrexed-Gemcitabine Combination in Patients with Advanced-Stage Non-Small Cell Lung Cancer
Christian Monnerat; Thierry Le Chevalier; Karen Kelly; Coleman K. Obasaju; Julie Brahmer; Silvia Novello; Takashi Nakamura; Astra M. Liepa; Laurence Bozec; Paul A. Bunn, Jr; David S. Ettinger
A Phase I Trial of the Dual Farnesyltransferase and Geranylgeranyltransferase Inhibitor L-778,123 and Radiotherapy for Locally Advanced Pancreatic Cancer
Neil E. Martin; Thomas B. Brunner; Krystina D. Kiel; Thomas F. DeLaney; William F. Regine; Mohammed Mohiuddin; Ernest F. Rosato; Daniel G. Haller; James P. Stevenson; Debbie Smith; Barnali Pramanik; Joel Tepper; Wesley K. Tanaka; Briggs Morrison; Paul Deutsch; Anjali K. Gupta; Ruth J. Muschel; W. Gillies McKenna; Eric J. Bernhard; Stephen M. Hahn
Research Articles
Molecular Oncology, Markers, Clinical Correlates
CXC Chemokine Receptor 3 and CC Chemokine Receptor 4 Expression in T-Cell and NK-Cell Lymphomas with Special Reference to Clinicopathological Significance for Peripheral T-Cell Lymphoma, Unspecified
Takashi Ishida; Hiroshi Inagaki; Atae Utsunomiya; Yoshifusa Takatsuka; Hirokazu Komatsu; Shinsuke Iida; Genji Takeuchi; Tadaaki Eimoto; Shigeo Nakamura; Ryuzo Ueda
Nuclear Factor-κB Is Constitutively Activated in Prostate Cancer In vitro and Is Overexpressed in Prostatic Intraepithelial Neoplasia and Adenocarcinoma of the Prostate
Christopher Sweeney; Lang Li; Rajasubramaniam Shanmugam; Poornima Bhat-Nakshatri; Vetrichelvan Jayaprakasan; Lee Ann Baldridge; Thomas Gardner; Martin Smith; Harikrishna Nakshatri; Liang Cheng
Expression Level of Valosin-Containing Protein (p97) Is Associated with Prognosis of Esophageal Carcinoma
Shinji Yamamoto; Yasuhiko Tomita; Yoshihiko Hoshida; Norishige Iizuka; Shinya Kidogami; Hiroshi Miyata; Shuji Takiguchi; Yoshiyuki Fujiwara; Takushi Yasuda; Masahiko Yano; Shoji Nakamori; Masato Sakon; Morito Monden; Katsuyuki Aozasa
The Membrane-Anchored Matrix Metalloproteinase (MMP) Regulator RECK in Combination with MMP-9 Serves as an Informative Prognostic Indicator for Colorectal Cancer
Taku Takeuchi; Michiyoshi Hisanaga; Mitsuo Nagao; Naoya Ikeda; Hisao Fujii; Fumikazu Koyama; Tomohide Mukogawa; Hiroshi Matsumoto; Shunya Kondo; Chiaki Takahashi; Makoto Noda; Yoshiyuki Nakajima
Expression of the ELAV-Like Protein HuR Is Associated with Higher Tumor Grade and Increased Cyclooxygenase-2 Expression in Human Breast Carcinoma
Carsten Denkert; Wilko Weichert; Klaus-Jürgen Winzer; Berit-Maria Müller; Aurelia Noske; Silvia Niesporek; Glen Kristiansen; Hans Guski; Manfred Dietel; Steffen Hauptmann
Experimental Therapeutics, Preclinical Pharmacology
In vitro and In vivo Activity of the Nuclear Factor-κB Inhibitor Sulfasalazine in Human Glioblastomas
Pierre A. Robe; Mohamed Bentires-Alj; Marianne Bonif; Bernard Rogister; Manuel Deprez; Heddi Haddada; Minh-Tuan Nguyen Khac; Olivier Jolois; Kadir Erkmen; Marie-Paule Merville; Peter M. Black; Vincent Bours
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