Granulosa cell tumors, Sertoli-Leydig tumors, and small cell hypercalcemic ovarian cancers are clinically and biologically distinct. In the past few years the key mutations underpinning these mutations have been discovered. This has led to improved diagnostics for granulosa cell tumors and small cell hypercalcemic ovarian cancer. The discovery of pathognomonic mutations has led to the development of model systems and a better understanding of all three cancer types and for small cell ovarian cancer new treatment strategies.

Citation Format: David Huntsman. Granulosa cell and other rare ovarian cancers: Genomic-derived diagnostics and emergent management strategies. [abstract]. In: Proceedings of the AACR Conference: Addressing Critical Questions in Ovarian Cancer Research and Treatment; Oct 1-4, 2017; Pittsburgh, PA. Philadelphia (PA): AACR; Clin Cancer Res 2018;24(15_Suppl):Abstract nr IA19.

©2018 American Association for Cancer Research.
2018
American Association for Cancer Research.