The article entitled “Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression,” which was published in the January 15, 2010, issue of Clinical Cancer Research [CCR (1)], is being retracted at the request of the AACR Publications Department and the CCR Editor-in-Chief. A reader presented evidence of duplicate and/or redundant publication in two articles by Wei and colleagues published in two AACR journals. The articles in question, “Glioblastoma Cancer-Initiating Cells Inhibit T-cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway” (2) and “Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression,” were published, respectively, in the January 2010 issue of Molecular Cancer Therapeutics and the January 15, 2010, issue of CCR. The editors of both journals and AACR Publications Department members investigated the matter further. We found that identical text was presented in the Materials and Methods and Results sections of both articles. In addition, the submission of these papers was nearly simultaneous, and neither paper made reference to the existence of the other. We contacted the corresponding author of the study to express our concerns, and, after several rounds of correspondence, suggested she notify her institution's Office of Research Integrity (or comparable authority). After extensive review of the responses to our queries from the author and representatives from her institution's Office of Research Integrity, we have determined that this is a case of redundant and/or duplicate publication as defined by the U.S. Department of Health and Human Services Office of Research Integrity standards (http://ori.hhs.gov/plagiarism-14).

It is our responsibility to correct the published record. In cases of redundant and/or duplicate publication, the Committee on Publication Ethics (COPE) recommends retraction of the redundant and/or duplicate article. Thus, the article entitled “Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression,” which was published online in CCR on January 12, 2010, will be retracted; the article entitled “Glioblastoma Cancer-Initiating Cells Inhibit T-cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway,” which was published online in Molecular Cancer Therapeutics on January 6, 2010, will remain unchanged. A copy of this notice was sent to the authors.

1.
Wei
J
,
Barr
J
,
Kong
LY
,
Wang
Y
,
Wu
A
,
Sharma
AK
, et al
Glioma-associated cancer-initiating cells induce immunosuppression
.
Clin Cancer Res
2010
;
16
:
461
73
.
2.
Wei
J
,
Barr
J
,
Kong
LY
,
Wang
Y
,
Wu
A
,
Sharma
AK
, et al
Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway
.
Mol Cancer Ther
2010
;
9
:
67
78
.