PET Imaging of Nectin-4: A Promising Tool for Personalized/Precision Oncology Available to Purchase

In a recent study, the authors developed a nectin-4–targeting bicyclic peptide–based radiotracer, ⁶⁸Ga-N188, for PET imaging of advanced urothelial cancer. Preclinical investigation and first-in-human study in 14 patients demonstrated excellent specificity and sensitivity of ⁶⁸Ga-N188 in detecting metastases. These promising results support ⁶⁸Ga-N188 as a companion diagnostic for future personalized cancer therapy.

See related article by Duan et al., p. 3395