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1 October 2020
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Cover Image
Cover Image
The cover is adapted from Figure 1 in the article, “Environmental Quality and Invasive Breast Cancer,” by Gearhart-Serna and colleagues. The figure shows the environmental quality index (EQI) stratified by rural–urban categories by county. To test the hypothesis that the incidence of specific breast cancer stages can vary by demographics in relation to environmental factors, Gearhart-Serna and colleagues utilized EQI datasets to investigate associations between environmental factors and breast cancer compared to carcinoma in situ. Cumulatively, the results suggest that some broad measures of environmental quality are associated with invasive breast cancer, but that associations vary by environmental domain, cancer stage, subtype, and urbanicity. The study demonstrates the strongest positive association for poor land environmental quality and distant metastatic breast cancer. For more information, see the article beginning on page 1920.Close Modal
The article is included in the CEBP Focus, “Environmental Carcinogenesis: Pathways to Prevention,” published in this issue. The AACR convened a Special Conference entitled, “Environmental Carcinogenesis: Potential Pathway to Prevention,” held June 22 to 24, 2019, in Charlotte, NC, and cochaired by Margaret Kripke, Ernest Hawk, and Timothy Rebbeck. A goal of the meeting was to review and analyze evidence for the role of environmental factors in cancer development and discuss how this information could be applied to prevent cancer. The meeting also provided a forum for discussion of these issues among diverse groups, including cancer biologists, epidemiologists, toxicologists, advocates, community leaders, and communication specialists, who rarely have opportunities to interact. The Focus included in this issue represents but a few of the resulting collaborations. For more information, see the Focus section beginning on page 1869. - PDF Icon PDF LinkTable of Contents
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ISSN 1055-9965
EISSN 1538-7755
Issue Sections
Highlights
Commentary
Reviews
CEBP Focus
The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them
Martyn T. Smith; Kathryn Z. Guyton; Nicole Kleinstreuer; Alexandre Borrel; Andres Cardenas; Weihsueh A. Chiu; Dean W. Felsher; Catherine F. Gibbons; William H. Goodson, III; Keith A. Houck; Agnes B. Kane; Michele A. La Merrill; Herve Lebrec; Leroy Lowe; Cliona M. McHale; Sheroy Minocherhomji; Linda Rieswijk; Martha S. Sandy; Hideko Sone; Amy Wang; Luoping Zhang; Lauren Zeise; Mark Fielden
Applying Tobacco, Environmental, and Dietary-Related Biomarkers to Understand Cancer Etiology and Evaluate Prevention Strategies
Lisa A. Peterson; Silvia Balbo; Naomi Fujioka; Dorothy K. Hatsukami; Stephen S. Hecht; Sharon E. Murphy; Irina Stepanov; Natalia Y. Tretyakova; Robert J. Turesky; Peter W. Villalta
Research Articles
Verification of a Blood-Based Targeted Proteomics Signature for Malignant Pleural Mesothelioma
Ferdinando Cerciello; Meena Choi; Sara L. Sinicropi-Yao; Katie Lomeo; Joseph M. Amann; Emanuela Felley-Bosco; Rolf A. Stahel; Bruce W.S. Robinson; Jenette Creaney; Harvey I. Pass; Olga Vitek; David P. Carbone
Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium
Yonathan Brhane; Ping Yang; David C. Christiani; Geoffrey Liu; John R. McLaughlin; Paul Brennan; Sanjay Shete; John K. Field; Adonina Tardón; Takashi Kohno; Kouya Shiraishi; Keitaro Matsuo; Yohan Bossé; Christopher I. Amos; Rayjean J. Hung
Ovarian Cancer Risk Factor Associations by Primary Anatomic Site: The Ovarian Cancer Cohort Consortium
Renée T. Fortner; Megan S. Rice; Synnove F. Knutsen; Michael J. Orlich; Kala Visvanathan; Alpa V. Patel; Mia M. Gaudet; Anne Tjønneland; Marina Kvaskoff; Rudolf Kaaks; Antonia Trichopolou; Valeria Pala; N. Charlotte Onland-Moret; Inger T. Gram; Pilar Amiano; Annika Idahl; Naomi E. Allen; Elisabete Weiderpass; Jenny N. Poynter; Kim Robien; Graham G. Giles; Roger L. Milne; Veronica W. Setiawan; Melissa A. Merritt; Piet A. van den Brandt; Anne Zeleniuch-Jacquotte; Alan A. Arslan; Katie M. O'Brien; Dale P. Sandler; Alicja Wolk; Niclas Håkansson; Holly R. Harris; Britton Trabert; Nicolas Wentzensen; Shelley S. Tworoger; Leo J. Schouten
Stochastic Epigenetic Mutations Are Associated with Risk of Breast Cancer, Lung Cancer, and Mature B-cell Neoplasms
Amedeo Gagliardi; Pierre-Antoine Dugué; Therese H. Nøst; Melissa C. Southey; Daniel D. Buchanan; Daniel F. Schmidt; Enes Makalic; Allison M. Hodge; Dallas R. English; Nicole W. Doo; John L. Hopper; Gianluca Severi; Laura Baglietto; Alessio Naccarati; Sonia Tarallo; Luigia Pace; Vittorio Krogh; Domenico Palli; Salvatore Panico; Carlotta Sacerdote; Rosario Tumino; Eiliv Lund; Graham G. Giles; Barbara Pardini; Torkjel M. Sandanger; Roger L. Milne; Paolo Vineis; Silvia Polidoro; Giovanni Fiorito
Breast Cancer Population Attributable Risk Proportions Associated with Body Mass Index and Breast Density by Race/Ethnicity and Menopausal Status
Michael C.S. Bissell; Karla Kerlikowske; Brian L. Sprague; Jeffery A. Tice; Charlotte C. Gard; Katherine Y. Tossas; Garth H. Rauscher; Amy Trentham-Dietz; Louise M. Henderson; Tracy Onega; Theresa H.M. Keegan; Diana L. Miglioretti; for the Breast Cancer Surveillance Consortium
Independent and Joint Associations between Serum Calcium, 25-Hydroxy Vitamin D, and the Risk of Primary Liver Cancer: A Prospective Nested Case–Control Study
Jian Yin; Liang-Yu Yin; Neal D. Freedman; Ting-Yuan Li; Sanford M. Dawsey; Jian-Feng Cui; Philip R. Taylor; Bin Liu; Jin-Hu Fan; Wen Chen; Christian C. Abnet; You-Lin Qiao
Glomerular Hyperfiltration and Cancer: A Nationwide Population-Based Study
Yaerim Kim; Soojin Lee; Yeonhee Lee; Min Woo Kang; Sehoon Park; Sanghyun Park; Kyungdo Han; Jin Hyuk Paek; Woo Yeong Park; Kyubok Jin; Seungyeup Han; Seung Seok Han; Hajeong Lee; Jung Pyo Lee; Kwon Wook Joo; Chun Soo Lim; Yon Su Kim; Dong Ki Kim
Human Papillomavirus Genotypes in Anal High-Grade Squamous Intraepithelial Lesion (HSIL): Anal Intraepithelial Neoplasia Grades 2 (AIN2) and 3 (AIN3) Are Different
Jennifer M. Roberts; Isobel M. Poynten; Monica Molano; Dorothy A. Machalek; Richard J. Hillman; Patricia Guzman; Fengyi Jin; David J. Templeton; Christopher K. Fairley; Carmella Law; Suzanne M. Garland; Andrew E. Grulich; Alyssa M. Cornall
Racial Differences in Helicobacter pylori CagA Sero-prevalence in a Consortium of Adult Cohorts in the United States
Matthew G. Varga; Julia Butt; William J. Blot; Loïc Le Marchand; Christopher A. Haiman; Yu Chen; Sylvia Wassertheil-Smoller; Lesley F. Tinker; Richard M. Peek, Jr; John D. Potter; Timothy L. Cover; Terry Hyslop; Anne Zeleniuch-Jacquotte; Sonja I. Berndt; Allan Hildesheim; Tim Waterboer; Michael Pawlita; Meira Epplein
Null Results in Brief
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