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Volume 14, Issue 4
1 April 2005
Issue Cover
All Issues
ISSN 1055-9965
EISSN 1538-7755

Editorial

A Risk Prediction Tool for Melanoma?
David C. Whiteman; Adèle C. Green
View articletitled, A Risk Prediction Tool for Melanoma?
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Meeting Reports

The Biology of Tobacco and Nicotine: Bench to Bedside
Phillip A. Dennis; Carter Van Waes; J. Silvio Gutkind; Kenneth J. Kellar; Charles Vinson; Alexey G. Mukhin; Margaret R. Spitz; Joan E. Bailey-Wilson; Grace Chao Yeh; Lucy M. Anderson; Jonathan S. Wiest
View articletitled, The Biology of Tobacco and Nicotine: Bench to Bedside
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Hypothesis/Commentary

Epidemiology and Prevention of Breast Cancer
Graham A. Colditz
View articletitled, Epidemiology and Prevention of Breast Cancer
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Review

Chlamydia pneumoniae and Lung Cancer: Epidemiologic Evidence
Alyson J. Littman; Lisa A. Jackson; Thomas L. Vaughan
View articletitled, <em>Chlamydia pneumoniae</em> and Lung Cancer: Epidemiologic Evidence
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Research Articles

Physical Activity and Risk of Endometrial Cancer: A Report from the Shanghai Endometrial Cancer Study
Charles E. Matthews; Wang Hong Xu; Wei Zheng; Yu Tang Gao; Zhi Xian Ruan; Jia Rong Cheng; Yong Bing Xiang; Xiao Ou Shu
View articletitled, Physical Activity and Risk of Endometrial Cancer: A Report from the Shanghai Endometrial Cancer Study
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Ki-67 Expression in Benign Breast Ductal Cells Obtained by Random Periareolar Fine Needle Aspiration
Qamar J. Khan; Bruce F. Kimler; Julie Clark; Trina Metheny; Carola M. Zalles; Carol J. Fabian
View articletitled, Ki-67 Expression in Benign Breast Ductal Cells Obtained by Random Periareolar Fine Needle Aspiration
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Retinoic Acid Receptor-β2 Promoter Methylation in Random Periareolar Fine Needle Aspiration
Gregory R. Bean; Victoria Scott; Lisa Yee; Brooke Ratliff-Daniel; Michelle M. Troch; Pearl Seo; Michelle L. Bowie; Paul K. Marcom; Jaimie Slade; Bruce F. Kimler; Carol J. Fabian; Carola M. Zalles; Gloria Broadwater; Joseph C. Baker, Jr.; Lee G. Wilke; Victoria L. Seewaldt
View articletitled, Retinoic Acid Receptor-β2 Promoter Methylation in Random Periareolar Fine Needle Aspiration
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Postmenopausal Breast Cancer Risk and Cumulative Number of Menstrual Cycles
Mariana Chavez-MacGregor; Sjoerd G. Elias; N. Charlotte Onland-Moret; Yvonne T. van der Schouw; Carla H. Van Gils; Evelyn Monninkhof; Diederick E. Grobbee; Petra H.M. Peeters
View articletitled, Postmenopausal Breast Cancer Risk and Cumulative Number of Menstrual Cycles
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Flavonoids and Breast Cancer Risk in Italy
Cristina Bosetti; Luana Spertini; Maria Parpinel; Patrizia Gnagnarella; Pagona Lagiou; Eva Negri; Silvia Franceschi; Maurizio Montella; Julie Peterson; Johanna Dwyer; Attilio Giacosa; Carlo La Vecchia
View articletitled, Flavonoids and Breast Cancer Risk in Italy
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Lack of Association between EBV and Breast Carcinoma
Jacqueline G. Perrigoue; Johan A. den Boon; Andreas Friedl; Michael A. Newton; Paul Ahlquist; Bill Sugden
View articletitled, Lack of Association between EBV and Breast Carcinoma
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Cyp17, Urinary Sex Steroid Levels and Breast Cancer Risk in Postmenopausal Women
N. Charlotte Onland-Moret; Carla H. van Gils; Mark Roest; Diederick E. Grobbee; Petra H.M. Peeters
View articletitled, Cyp17, Urinary Sex Steroid Levels and Breast Cancer Risk in Postmenopausal Women
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Genetic Polymorphisms of Ataxia Telangiectasia Mutated and Breast Cancer Risk
Kyoung-Mu Lee; Ji-Yeob Choi; Sue Kyung Park; Hye-Won Chung; Byungchan Ahn; Keun-Young Yoo; Wonshik Han; Dong-Young Noh; Sei-Hyun Ahn; Ho Kim; Qingyi Wei; Daehee Kang
View articletitled, Genetic Polymorphisms of Ataxia Telangiectasia Mutated and Breast Cancer Risk
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Increased Retinoic Acid Receptor-β4 Correlates In vivo with Reduced Retinoic Acid Receptor-β2 in Esophageal Squamous Cell Carcinoma
Xiao-chun Xu; J. Jack Lee; Tsung-Teh Wu; Ashraful Hoque; Jeffer A. Ajani; Scott M. Lippman
View articletitled, Increased Retinoic Acid Receptor-β<sub>4</sub> Correlates <em>In vivo</em> with Reduced Retinoic Acid Receptor-β<sub>2</sub> in Esophageal Squamous Cell Carcinoma
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Frequent Methylation of Eyes Absent 4 Gene in Barrett's Esophagus and Esophageal Adenocarcinoma
Hongzhi Zou; Neal K. Osborn; Jonathan J. Harrington; Kristie K. Klatt; Julian R. Molina; Lawrence J. Burgart; David A. Ahlquist
View articletitled, Frequent Methylation of <em>Eyes Absent 4</em> Gene in Barrett's Esophagus and Esophageal Adenocarcinoma
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Dietary Marine n-3 Fatty Acids in Relation to Risk of Distal Colorectal Adenoma in Women
Kyungwon Oh; Walter C. Willett; Charles S. Fuchs; Edward Giovannucci
View articletitled, Dietary Marine <em>n</em>-3 Fatty Acids in Relation to Risk of Distal Colorectal Adenoma in Women
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Fiber Intake and Incidence of Colorectal Cancer among 76,947 Women and 47,279 Men
Karin B. Michels; Charles S. Fuchs; Edward Giovannucci; Graham A. Colditz; David J. Hunter; Meir J. Stampfer; Walter C. Willett
View articletitled, Fiber Intake and Incidence of Colorectal Cancer among 76,947 Women and 47,279 Men
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A Prospective Study of C-Peptide, Insulin-like Growth Factor-I, Insulin-like Growth Factor Binding Protein-1, and the Risk of Colorectal Cancer in Women
Esther K. Wei; Jing Ma; Michael N. Pollak; Nader Rifai; Charles S. Fuchs; Susan E. Hankinson; Edward Giovannucci
View articletitled, A Prospective Study of C-Peptide, Insulin-like Growth Factor-I, Insulin-like Growth Factor Binding Protein-1, and the Risk of Colorectal Cancer in Women
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Detection of Alkaline Sphingomyelinase Activity in Human Stool: Proposed Role as a New Diagnostic and Prognostic Marker of Colorectal Cancer
Luisa Di Marzio; Alfredo Di Leo; Benedetta Cinque; Donatella Fanini; Alessio Agnifili; Pasquale Berloco; Michele Linsalata; Dionigi Lorusso; Michele Barone; Claudio De Simone; Maria Grazia Cifone
View articletitled, Detection of Alkaline Sphingomyelinase Activity in Human Stool: Proposed Role as a New Diagnostic and Prognostic Marker of Colorectal Cancer
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APC Asp1822Val and Gly2502Ser Polymorphisms and Risk of Colorectal Cancer and Adenoma
Gregory J. Tranah; Edward Giovannucci; Jing Ma; Charles Fuchs; David J. Hunter
View articletitled, <em>APC</em> Asp1822Val and Gly2502Ser Polymorphisms and Risk of Colorectal Cancer and Adenoma
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The T393C Polymorphism of the Gαs Gene (GNAS1) Is a Novel Prognostic Marker in Bladder Cancer
Ulrich H. Frey; Andreas Eisenhardt; Gerd Lümmen; Herbert Rübben; Karl-Heinz Jöckel; Kurt W. Schmid; Winfried Siffert
View articletitled, The T393C Polymorphism of the Gαs Gene (<em>GNAS1</em>) Is a Novel Prognostic Marker in Bladder Cancer
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Polymorphisms in XPD Exons 10 and 23 and Bladder Cancer Risk
Matthew B. Schabath; George L. Delclos; H. Barton Grossman; Yunfei Wang; Seth P. Lerner; Robert M. Chamberlain; Margaret R. Spitz; Xifeng Wu
View articletitled, Polymorphisms in <em>XPD</em> Exons 10 and 23 and Bladder Cancer Risk
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Tobacco-Specific Nitrosamines and Their Pyridine-N-glucuronides in the Urine of Smokers and Smokeless Tobacco Users
Irina Stepanov; Stephen S. Hecht
View articletitled, Tobacco-Specific Nitrosamines and Their Pyridine-<em>N</em>-glucuronides in the Urine of Smokers and Smokeless Tobacco Users
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Safety and Efficacy of Weekly Oral Oltipraz in Chronic Smokers
Michael J. Kelley; Elizabeth M. Glaser; James E. Herndon, II; Frank Becker; Rajesh Bhagat; Yu-Jing Zhang; Regina M. Santella; Steven G. Carmella; Stephen S. Hecht; Lilia Gallot; Lawrence Schilder; James A. Crowell; Marjorie Perloff; Rodney J. Folz; Raymond C. Bergan
View articletitled, Safety and Efficacy of Weekly Oral Oltipraz in Chronic Smokers
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Evaluation of Risk Factors for Nasopharyngeal Carcinoma in High-Risk Nasopharyngeal Carcinoma Families in Taiwan
Xiaohong (Rose) Yang; Scott Diehl; Ruth Pfeiffer; Chien-Jen Chen; Wan-Lun Hsu; Mustafa Dosemeci; Yu-Juen Cheng; Brenda Sun; Alisa M. Goldstein; Allan Hildesheim; The Chinese and American Genetic Epidemiology of NPC Study Team
View articletitled, Evaluation of Risk Factors for Nasopharyngeal Carcinoma in High-Risk Nasopharyngeal Carcinoma Families in Taiwan
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Fatty Acid Composition of Red Blood Cell Membranes and Risk of Squamous Cell Carcinoma of the Skin
Robin B. Harris; Janet A. Foote; Iman A. Hakim; Dan L. Bronson; David S. Alberts
View articletitled, Fatty Acid Composition of Red Blood Cell Membranes and Risk of Squamous Cell Carcinoma of the Skin
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No Evidence for BRAF as a Melanoma/Nevus Susceptibility Gene
Sharon Jackson; Mark Harland; Faye Turner; Claire Taylor; Philip A. Chambers; Juliette Randerson-Moor; Anthony J. Swerdlow; Isabel dos Santos Silva; Samantha Beswick; D. Timothy Bishop; Julia A. Newton Bishop
View articletitled, No Evidence for <em>BRAF</em> as a Melanoma/Nevus Susceptibility Gene
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Intraindividual Variability in Arsenic Methylation in a U.S. Population
Craig Steinmaus; Yan Yuan; Dave Kalman; Raja Atallah; Allan H. Smith
View articletitled, Intraindividual Variability in Arsenic Methylation in a U.S. Population
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Cigarette Smoking and Risk of Non-Hodgkin Lymphoma: A Pooled Analysis from the International Lymphoma Epidemiology Consortium (InterLymph)
Lindsay M. Morton; Patricia Hartge; Theodore R. Holford; Elizabeth A. Holly; Brian C.H. Chiu; Paolo Vineis; Emanuele Stagnaro; Eleanor V. Willett; Silvia Franceschi; Carlo La Vecchia; Ann Maree Hughes; Wendy Cozen; Scott Davis; Richard K. Severson; Leslie Bernstein; Susan T. Mayne; Fred R. Dee; James R. Cerhan; Tongzhang Zheng
View articletitled, Cigarette Smoking and Risk of Non-Hodgkin Lymphoma: A Pooled Analysis from the International Lymphoma Epidemiology Consortium (InterLymph)
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Residential Herbicide Use and Risk of Non-Hodgkin Lymphoma
Patricia Hartge; Joanne S. Colt; Richard K. Severson; James R. Cerhan; Wendy Cozen; David Camann; Shelia Hoar Zahm; Scott Davis
View articletitled, Residential Herbicide Use and Risk of Non-Hodgkin Lymphoma
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The MTHFR 1298A>C Polymorphism and Genomic DNA Methylation in Human Lymphocytes
Simonetta Friso; Domenico Girelli; Elisabetta Trabetti; Oliviero Olivieri; Patrizia Guarini; Pier Franco Pignatti; Roberto Corrocher; Sang-Woon Choi
View articletitled, The <em>MTHFR 1298A&gt;C</em> Polymorphism and Genomic DNA Methylation in Human Lymphocytes
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Dietary Folate and Risk of Prostate Cancer in Italy
Claudio Pelucchi; Carlotta Galeone; Renato Talamini; Eva Negri; Maria Parpinel; Silvia Franceschi; Maurizio Montella; Carlo La Vecchia
View articletitled, Dietary Folate and Risk of Prostate Cancer in Italy
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Association of Susceptibility Alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with Prostate Cancer Severity in European American and African American Men
Hanna Rennert; Charnita M. Zeigler-Johnson; Kathakali Addya; Matthew J. Finley; Amy H. Walker; Elaine Spangler; Debra G.B. Leonard; Alan Wein; S. Bruce Malkowicz; Timothy R. Rebbeck
View articletitled, Association of Susceptibility Alleles in <em>ELAC2/HPC2</em>, <em>RNASEL/HPC1</em>, and <em>MSR1</em> with Prostate Cancer Severity in European American and African American Men
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A DNA Pooling Strategy for Family-Based Association Studies
Wen-Chung Lee
View articletitled, A DNA Pooling Strategy for Family-Based Association Studies
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Lifestyle Determinants and Mortality in German Vegetarians and Health-Conscious Persons: Results of a 21-Year Follow-up
Jenny Chang-Claude; Silke Hermann; Ursula Eilber; Karen Steindorf
View articletitled, Lifestyle Determinants and Mortality in German Vegetarians and Health-Conscious Persons: Results of a 21-Year Follow-up
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Genotyping of Patients with Sporadic and Radiation-Associated Meningiomas
Siegal Sadetzki; Pazit Flint-Richter; Sigal Starinsky; Ilya Novikov; Yehuda Lerman; Boleslaw Goldman; Eitan Friedman
View articletitled, Genotyping of Patients with Sporadic and Radiation-Associated Meningiomas
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Short Communications

The Effect of a School-Based Sun Protection Intervention on the Development of Melanocytic Nevi in Children: 6-Year Follow-up
Dallas R. English; Elizabeth Milne; Peter Jacoby; Billie Giles-Corti; Donna Cross; Robyn Johnston
View articletitled, The Effect of a School-Based Sun Protection Intervention on the Development of Melanocytic Nevi in Children: 6-Year Follow-up
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Multiplexed Immunobead-Based Cytokine Profiling for Early Detection of Ovarian Cancer
Elieser Gorelik; Douglas P. Landsittel; Adele M. Marrangoni; Francesmary Modugno; Lyudmila Velikokhatnaya; Matthew T. Winans; William L. Bigbee; Ronald B. Herberman; Anna E. Lokshin
View articletitled, Multiplexed Immunobead-Based Cytokine Profiling for Early Detection of Ovarian Cancer
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Serum Trans-Fatty Acids Are Associated with Risk of Prostate Cancer in β-Carotene and Retinol Efficacy Trial
Irena B. King; Alan R. Kristal; Steve Schaffer; Mark Thornquist; Gary E. Goodman
View articletitled, Serum <em>Trans</em>-Fatty Acids Are Associated with Risk of Prostate Cancer in β-Carotene and Retinol Efficacy Trial
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The E211 G>A Androgen Receptor Polymorphism Is Associated with a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
Vanessa M. Hayes; Gianluca Severi; Sarah A. Eggleton; Emma J.D. Padilla; Melissa C. Southey; Robert L. Sutherland; John L. Hopper; Graham G. Giles
View articletitled, The E211 G&gt;A Androgen Receptor Polymorphism Is Associated with a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
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Genetic Variants in the Vitamin D Receptor Gene and Prostate Cancer Risk
Vanessa M. Hayes; Gianluca Severi; Emma J.D. Padilla; Sarah A. Eggleton; Melissa C. Southey; Robert L. Sutherland; John L. Hopper; Graham G. Giles
View articletitled, Genetic Variants in the Vitamin D Receptor Gene and Prostate Cancer Risk
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Levels of Physical Activity for Colon Cancer Prevention Compared with Generic Public Health Recommendations: Population Prevalence and Sociodemographic Correlates
Ester Cerin; Eva Leslie; Adrian Bauman; Neville Owen
View articletitled, Levels of Physical Activity for Colon Cancer Prevention Compared with Generic Public Health Recommendations: Population Prevalence and Sociodemographic Correlates
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Utilization of BRCA1/BRCA2 Mutation Testing in Newly Diagnosed Breast Cancer Patients
Marc D. Schwartz; Caryn Lerman; Barbara Brogan; Beth N. Peshkin; Claudine Isaacs; Tiffani DeMarco; Chanita Hughes Halbert; Marie Pennanen; Clinton Finch
View articletitled, Utilization of BRCA1/BRCA2 Mutation Testing in Newly Diagnosed Breast Cancer Patients
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Age-Specific Incidence Rates of In situ Breast Carcinomas by Histologic Type, 1980 to 2001
Christopher I. Li; Janet R. Daling; Kathleen E. Malone
View articletitled, Age-Specific Incidence Rates of <em>In situ</em> Breast Carcinomas by Histologic Type, 1980 to 2001
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Cimetidine and Other Histamine2-Receptor Antagonist Use in Relation to Risk of Breast Cancer
Patricia F. Coogan; Yuqing Zhang; Julie R. Palmer; Brian L. Strom; Lynn Rosenberg
View articletitled, Cimetidine and Other Histamine<sub>2</sub>-Receptor Antagonist Use in Relation to Risk of Breast Cancer
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Effects of Electron-Beam Irradiation on Whole Genome Amplification
Andrew W. Bergen; Ying Qi; Kashif A. Haque; Robert A. Welch; Montserrat Garcia-Closas; Stephen J. Chanock; Jim Vaught; Philip E. Castle
View articletitled, Effects of Electron-Beam Irradiation on Whole Genome Amplification
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Null Results in Brief

No Effect of Exercise on Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 in Postmenopausal Women: a 12-Month Randomized Clinical Trial
Anne McTiernan; Bess Sorensen; Yutaka Yasui; Shelley S. Tworoger; Cornelia M. Ulrich; Melinda L. Irwin; Rebecca E. Rudolph; Frank Z. Stanczyk; Robert S. Schwartz; John D. Potter
View articletitled, No Effect of Exercise on Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 in Postmenopausal Women: a 12-Month Randomized Clinical Trial
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No Excess Risk of Breast Cancer among Female Users of Systemic Glucocorticoids
Henrik Toft Sørensen; Lene Mellemkjær; Mette Vinther Skriver; Timothy L. Lash; Jørgen H. Olsen; John A. Baron
View articletitled, No Excess Risk of Breast Cancer among Female Users of Systemic Glucocorticoids
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No Association of Meat, Fish, and Egg Consumption with Ovarian Cancer Risk
Susanna C. Larsson; Alicja Wolk
View articletitled, No Association of Meat, Fish, and Egg Consumption with Ovarian Cancer Risk
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Reported Use of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Was Not Associated with Reduced Recurrence of Colorectal Adenomas
Jeffrey T. Wei; Leila A. Mott; John A. Baron; Robert S. Sandler; for the Polyp Prevention Study Group
View articletitled, Reported Use of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Was Not Associated with Reduced Recurrence of Colorectal Adenomas
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No Association between Cytochrome P450 and Glutathione S-Transferase Gene Polymorphisms and Risk of Colorectal Adenoma: Results from the UK Flexible Sigmoidoscopy Screening Trial
Marc J. Gunter; Mark A. Watson; Alexandre S. Loktionov; Panagiota Mitrou; Tom Cecil; Christopher Macklin; Christopher Cardwell; D. Timothy Bishop; John Primrose; Wendy S. Atkin; Sheila A. Bingham
View articletitled, No Association between Cytochrome P450 and Glutathione <em>S</em>-Transferase Gene Polymorphisms and Risk of Colorectal Adenoma: Results from the UK Flexible Sigmoidoscopy Screening Trial
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TP53 Mutation Spectrum in Lung Cancer Is Not Different in Women and Men
Aizen J. Marrogi; Leah E. Mechanic; Judith A. Welsh; Elise D. Bowman; Mohammed A. Khan; Lindsey Enewold; Peter G. Shields; Curtis C. Harris
View articletitled, <em>TP53</em> Mutation Spectrum in Lung Cancer Is Not Different in Women and Men
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CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu Polymorphisms Are Not Associated with Risk of Squamous Cell Carcinoma of the Head and Neck
Guojun Li; Zhensheng Liu; Erich M. Sturgis; Robert M. Chamberlain; Margaret R. Spitz; Qingyi Wei
View articletitled, <em>CYP2E1</em> G1532C, <em>NQO1</em> Pro187Ser, and <em>CYP1B1</em> Val432Leu Polymorphisms Are Not Associated with Risk of Squamous Cell Carcinoma of the Head and Neck
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