Early-Onset Colorectal Cancer

Colorectal cancer (CRC) is the third most common cancer in men and the second most common cancer in women worldwide, and it remains the third leading cause of cancer deaths in the United States. Early-onset CRC, diagnosed in those under 50 years old, is increasing in incidence in the US and internationally. The reasons for these epidemiologic patterns are only recently being investigated and there remain gaps in our knowledge. This collection features recently published Cancer Epidemiology, Biomarkers & Prevention articles that investigate early-onset CRC and inform CRC screening and prevention recommendations.