Background Black men (BM) are statistically more likely to experience aggressive cases of prostate cancer (CaP) compared to other racial groups, but are less likely to enroll in clinical trials. Several barriers have been documented as impacting the participation of BM in clinical trials. To address these barriers, there is need for unique approaches to identify successful strategies that will facilitate the implementation of effective interventions. The overall goal of this study is to develop a tailored communication strategy for a CaP intervention trial, the MiCaP Research Digest Trial. Specifically, the primary objective was to identify the best intervention trial recruitment channels and locations for US-born BM (USBM), African-born BM (ABBM), and Caribbean-born BM (CBBM). Methods The MiCaP Research Digest Trial uses a randomized waitlist research design to evaluate the effectiveness of disseminating CaP scientific discoveries for public health and community applications. It is an ongoing trial, which started in 2017. The current study compared two channels (newspaper and radio) and four locations (churches, barber shops, community outreach events) relative to their effectiveness in recruiting BM for the trial. Study location was Orange County (FL). Recruitment efforts included newspaper stories about the study, study ad in newspaper, study ad on radio, information about study at community events and distribution of study flyers at targeted locations. Assessment focused on the following for the recruitment channels and locations: (1) reach, which was operationalized as the number of BM reached; and (2) impact, operationalized as the number of BM effectively pre-screened for the Trial. Results The study period is from May to July, 2019. Results presented are for data collected up to June 30, 2019. The reach for BM were: 30 community locations for newspaper; 27,000 people every week from the radio; 130 attendees for church events; an average of 12 customers per day for barber shops; and close to 1,200 attendees combined for the community events. The highest impact (uptake of the intervention trial) was from community events, with 8 BM recruited (6 USBM and 2 CBBM). One USBM was recruited through the newspaper and one USBBM through radio. There was no recruitment from church or the barbershop. Also, no ABBM has been recruited so far. Conclusion The reach for intervention trials does not necessarily translate to impact. Although the reach was highest for the radio, uptake of the intervention trial was highest for the community events. It was not surprising that the intervention trials uptake was highest for USBM. While 2 CBBM were recruited, recruiting ABBM continues to be challenging. Engaging ethnically-diverse BM through appropriate channels and locations is crucial to effective uptake of intervention trials.

Citation Format: Malcolm Ingraham, Folakemi Odedina, Parisa Fathi, Kim Walsh-Childers, Adaora Ezeani, Yaseen Elhag. Channels and locations influencing the uptake of prostate cancer intervention trials by ethnically diverse Black men [abstract]. In: Proceedings of the Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2019 Sep 20-23; San Francisco, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl_2):Abstract nr A044.