Prevalence of cigarette smoking is highest among American Indians, yet few culturally appropriate smoking cessation programs have yet been developed and tested for multi-tribal American Indian adult populations. This study tested for effectiveness the All Nations Breath of Life culturally tailored smoking cessation program in multi-tribal urban and suburban American Indian communities in 7 locations across 5 states (N=312).

This single-arm implementation effectiveness study used community-based participatory research to conduct a 12-week intervention. Participants were followed through month 6 in person and month 12 via telephone. The primary outcome was continuous abstinence from recreational cigarette smoking at 6 months post-baseline, verified through voluntary provision of salivary cotinine levels.

At program completion, 53.3% of program completers remained abstinent; using an intent-to-treat analysis labeling those lost to follow-up as smokers resulted in a 41.4% quit rate. At 6 months post-baseline, 31.1% of retained participants quit smoking (p<0.0001 compared to the highest quit rates among multi-tribal populations reported in the literature, 7%); final quit rate was 22.1% using an intent-to-treat analysis (p=0.002). Retention rate at endpoint was 71.2%. 12-month follow-up was attempted with all participants and had a retention rate of 49.0%. Of those participants reached, 34.0% were smoke-free; using an intent-to-treat analysis, the quit rate at 12 months post-baseline was 16.7%.

All Nations Breath of Life is an effective smoking cessation program for multi-tribal urban American Indian communities. It can be successfully implemented in a variety of urban settings.

Citation Format: Jordyn Gunville, Ryan Goeckenr, Jason Hale, T Edward Smith, Niaman Nazir, Sean Daley, Won Choi, Christine M. Daley. All Nations Breath of Life: A culturally tailored smoking cessation program for heterogeneous urban American Indian communities. [abstract]. In: Proceedings of the Ninth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2016 Sep 25-28; Fort Lauderdale, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2017;26(2 Suppl):Abstract nr A06.