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Short Communication|
April 02 2014
A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age
Habibul Ahsan;
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
Corresponding Author: Habibul Ahsan, University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60615. Phone: 773-834-9956; Fax: 773-834-0139; E-mail: habib@uchicago.edu
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Jerry Halpern;
Jerry Halpern
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Muhammad G. Kibriya;
Muhammad G. Kibriya
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Brandon L. Pierce;
Brandon L. Pierce
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Lin Tong;
Lin Tong
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Eric Gamazon;
Eric Gamazon
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Valerie McGuire;
Valerie McGuire
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Anna Felberg;
Anna Felberg
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Jianxin Shi;
Jianxin Shi
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Farzana Jasmine;
Farzana Jasmine
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Shantanu Roy;
Shantanu Roy
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Rachelle Brutus;
Rachelle Brutus
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Maria Argos;
Maria Argos
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Stephanie Melkonian;
Stephanie Melkonian
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Jenny Chang-Claude;
Jenny Chang-Claude
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Irene Andrulis;
Irene Andrulis
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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John L. Hopper;
John L. Hopper
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Esther M. John;
Esther M. John
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Kathi Malone;
Kathi Malone
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Giske Ursin;
Giske Ursin
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Marilie D. Gammon;
Marilie D. Gammon
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Duncan C. Thomas;
Duncan C. Thomas
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Daniela Seminara;
Daniela Seminara
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Graham Casey;
Graham Casey
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Julia A. Knight;
Julia A. Knight
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Melissa C. Southey;
Melissa C. Southey
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Graham G. Giles;
Graham G. Giles
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Regina M. Santella;
Regina M. Santella
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Eunjung Lee;
Eunjung Lee
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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David Conti;
David Conti
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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David Duggan;
David Duggan
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Steve Gallinger;
Steve Gallinger
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Robert Haile;
Robert Haile
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Mark Jenkins;
Mark Jenkins
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Noralane M. Lindor;
Noralane M. Lindor
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Polly Newcomb;
Polly Newcomb
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Kyriaki Michailidou;
Kyriaki Michailidou
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Carmel Apicella;
Carmel Apicella
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Daniel J. Park;
Daniel J. Park
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Julian Peto;
Julian Peto
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Olivia Fletcher;
Olivia Fletcher
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Isabel dos Santos Silva;
Isabel dos Santos Silva
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Mark Lathrop;
Mark Lathrop
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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David J. Hunter;
David J. Hunter
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Stephen J. Chanock;
Stephen J. Chanock
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Alfons Meindl;
Alfons Meindl
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Rita K. Schmutzler;
Rita K. Schmutzler
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Bertram Müller-Myhsok;
Bertram Müller-Myhsok
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Magdalena Lochmann;
Magdalena Lochmann
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Lars Beckmann;
Lars Beckmann
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Rebecca Hein;
Rebecca Hein
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Enes Makalic;
Enes Makalic
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Daniel F. Schmidt;
Daniel F. Schmidt
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Quang Minh Bui;
Quang Minh Bui
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Jennifer Stone;
Jennifer Stone
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Dieter Flesch-Janys;
Dieter Flesch-Janys
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Norbert Dahmen;
Norbert Dahmen
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Heli Nevanlinna;
Heli Nevanlinna
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Kristiina Aittomäki;
Kristiina Aittomäki
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Carl Blomqvist;
Carl Blomqvist
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Per Hall;
Per Hall
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Kamila Czene;
Kamila Czene
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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Astrid Irwanto;
Astrid Irwanto
Authors' Affiliations: 1Center for Cancer Epidemiology and Prevention; Departments of 2Health Studies, 3Medicine, and 4Human Genetics; 5Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; 6Department of Health Research and Policy, Stanford University School of Medicine; 7Stanford Cancer Institute, Stanford; 8Cancer Prevention Institute of California, Fremont; 9Department of Preventive Medicine, University of Southern California, Los Angeles; 10Stanford Cancer Institute, Palo Alto, California; 11Epidemiology and Genetics Research Program; 12Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; 13Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; 14Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 15Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; 16Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; 17Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; 18Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; 19Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; 20Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; 21Max Planck Institute of Psychiatry, Munich; 22Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, 23PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; 24Foundation for Quality and Efficiency in Health Care, Cologne; 25Department of Cancer Epidemiology/Clinical Cancer Registry; 26Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; 27Department of Psychiatry, University of Mainz, Mainz, Germany; 28Samuel Lunenfeld Research Institute; 29Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada; 30Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, Melbourne School of Population Health; 31Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne; 32Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Victoria, Australia; 33Norway Cancer Registry, Norway; Departments of 34Public Health and Primary Care and 35Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge; 36Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine; 37Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London; 38Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom; 39Centre National de Genotypage, Evry; 40Fondation Jean Dausset–CEPH, Paris, France; Departments of 41Obstetrics and Gynecology, 42Clinical Genetics, and 43Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 44Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 45Human Genetics Division, Genome Institute of Singapore, Singapore, Singapore; 46Department of Clinical Genetics, VU University Medical Center, Division of Oncogenetics, Amsterdam; and 47Department of Internal Medicine and Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands
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