We would like to correct errors in our epidemiologic literature review on DNA repair polymorphisms (Goode et al., CEBP 11:1513–30, 2002) that are the result of misinterpretation of the report by Xu et al. on OGG1 polymorphisms and prostate cancer risk (reference 47 in the paper).
Please make the following changes:
1. Page 1516, first paragraph:
Replace
“An increased risk associated with the CC genotype were also seen in analyses of prostate cancer (CC versus SS nonfamilial cases: adjusted OR, 3.3; 95% CI, 1.2–8.8; familial cases; adjusted OR, 2.1; 95% CI, 0.7–6.6; Ref. 47) and of esophageal cancer (CC versus SS/SC: OR, 1.9; 95% CI, 1.3–2.6; Ref. 34).”
with
“An increased risk associated with the CC genotype was also seen in an analysis of esophageal cancer (CC versus SS/SC: OR, 1.9; 95% CI, 1.3–2.6; Ref. 34), and a decreased risk was seen an analysis of prostate cancer (CC versus SS nonfamilial cases: adjusted OR, 0.3; 95% CI, 0.1–0.8; familial cases: adjusted OR, 0.5; 95% CI, 0.2–1.5; Ref. 47).”
2. Page 1518, Table 3, rows under the polymorphism S326C and cancer type of Prostate:
Replace
“3.3 (1.2–8.8)” and “2.1 (0.7–6.6)”
with
“0.3 (0.1–0.8)g” and “0.5 (0.2–1.5)g” [includes new reference to footnote g]
3. Page 1526, last paragraph:
Replace
“Primarily, the C allele at codon 326 in OGG1 (S326C) appeared to be associated with an increased risk in five case-control studies of esophageal cancer, lung cancer, and prostate cancer (34–36, 46–47); one study of stomach cancer found no association (56).”
with
“The C allele at codon 326 in OGG1 (S326C) appeared to be associated with an increased risk in four case-control studies of esophageal cancer and lung cancer (34–36, 46) and with decreased risk with prostate cancer (47); one study of stomach cancer found no association (56).”
Ellen L. Goode, Cornelia M. Ulrich, and John D. Potter
Fred Hutchinson Cancer Research Center
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