Abstract
Objective: To compare demographic and tumor characteristics, treatment, and overall and cancer-specific survival of non-Hispanic White and Hispanic women with endometrial cancer.
Background: Hispanics are one of the fastest growing minority groups in the U.S. Limited research has looked at age distribution, disease presentation, and outcome of endometrial cancer among ethnic minority women.
Methods: We used public use data from the SEER registry between 1992 and 2010. Inclusion criteria included non-Hispanic and Hispanic women who were diagnosed with endometrial cancer after 1992; not missing age, the first course of treatment, lymphadenectomy or lymph node status; and not diagnosed by autopsy or death certificate
Results: A total of 83,904 non-Hispanic and Hispanic patients were analyzed. Factors predictive of overall survival included being U.S.-born Hispanic, year of diagnosis, age at diagnosis, being single or other marital status, stage, histology-based risk, grade, extent of lymphadenectomy, and the first course of treatment. Factors predictive of cancer-specific survival included year of diagnosis, age at diagnosis, marital status, stage, other histology-based risk, grade, extent of lymphadenectomy, and the first course of treatment.
Conclusions: U.S.-born Hispanic women with endometrial cancer exhibited significantly poorer overall survival compared to non-Hispanic white women even after controlling for confounding variables. There was no difference in overall survival or cancer-specific survival between U.S.-born and foreign-born Hispanics compared to non-Hispanic Whites.
Citation Format: Ana M. Rodriguez, ThuyQuynh Ngoc Do. Overall endometrial cancer survival among non-Hispanic white and Hispanic women: A trend analysis of SEER reported cases 1992-2010. [abstract]. In: Proceedings of the Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Nov 9-12, 2014; San Antonio, TX. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2015;24(10 Suppl):Abstract nr A95.