The e-cigarette market is shifting toward higher nicotine products. This study by Dai and colleagues analyzed urinary biomarkers of exposure among exclusive adult e-cigarette users based on nicotine concentration levels using the nationally representative PATH Study Wave 5 (2018–2019) data. Results showed that e-cigarette users with nicotine-containing products had significantly higher levels of nicotine metabolites compared to non-nicotine vapers and non-tobacco users. Users of higher nicotine concentration e-cigarettes (1.8–4.9% and 5.0%+) exhibited greater exposure, although differences became insignificant after adjusting for covariates. The findings highlight the need for regulatory focus on nicotine content in e-cigarettes to manage nicotine exposure and mitigate potential health risks.

Despite an EU recommendation for Helicobacter pylori test-and-treat, many countries have not implemented such interventions due to low overall gastric cancer incidence. Identifying high-risk groups could facilitate targeted prevention. In this study by Mülder and colleagues, data from the Netherlands Cancer Registry were linked to demographic...

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