Evidence of a chemopreventive association between NSAIDs and pancreatic cancer risk is limited and conflicting. Randomized trials focus primarily on low-dose aspirin with few pancreatic cancer cases, while observational studies examining individual NSAIDs other than aspirin, or NSAIDs as a class, are scarce. Brasky and colleagues studied self-reported NSAID use and pancreatic cancer risk over 18 years in the Women’s Health Initiative, finding aspirin significantly reduced risk. No associations were observed for other formulations. In an exploratory analysis, the authors observed stronger associations for aspirin among women with prevalent diabetes. More large, prospective studies are needed to explore this association further.
National guidelines recommend fertility counseling for reproductive-age cancer patients who will receive gonadotoxic treatment. To enact fertility preservation, female patients must access a specialized fertility clinic. Rodriguez-Ormaza and colleagues assessed travel time to the nearest fertility clinic at diagnosis and receipt of fertility counseling. Women who lived ≥30 minutes...