To the Editor,

Gastric cancer is the fifth most common cancer and the leading cause of cancer-related deaths worldwide (1). Despite global declines in incidence rates of gastric cancer, there are emerging data to suggest that incidence rates of non-cardia gastric cancer among persons 50 years or younger [hereafter early-onset non-cardia gastric cancer (EOGC)] are increasing, with markedly higher rates among Hispanic persons as compared with non-Hispanic persons (2, 3). In a recent issue of Cancer Epidemiology, Biomarkers, & Prevention, Alagesan and colleagues review non-modifiable risk factors for gastric cancer, including race, ethnicity, and age (4). We appreciate the authors drawing attention to the changing gastric cancer burden worldwide, progress made to address this global burden, and remaining gaps. However, we believe that this review missed an opportunity to highlight emerging disparities in EOGC among Hispanic persons, the largest ethnic minority group in...

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