Acute lymphoblastic leukemia (ALL) accounts for 80% of all leukemias diagnosed in children. Although ALL age patterns are consistent across racial/ethnic groups, their incidence and mortality rates are highly variable. Montes-Rodríguez and colleagues assessed the age-standardized ALL incidence and mortality rates of Puerto Rican Hispanic (PRH) children and compared them with those of US mainland Hispanics, non-Hispanic whites, non-Hispanic blacks and Non-Hispanic Asian or Pacific Islanders. PRH children were found to have disparities in ALL incidence and mortality rates compared to other racial/ethnic groups in the US. Additional research is warranted to identify the genetic and environmental risk factors that may be associated with the disparities observed.

This study by Zhang and colleagues synthesized available epidemiological evidence on the associations of environmental and genetic factors with the risk of sporadic early-onset colorectal cancer (EOCRC) and early-onset advanced colorectal adenoma (EOCRA). A total of 61 studies were included, reporting 120 environmental...

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