The pesticide DDT is still used despite being an endocrine disruptor causing multi-generational harm in animals. Cirillo, La Merrill and colleagues used data from 3-generations of humans in the Child Health and Development Studies cohort. They report that grandmothers' perinatal serum DDT levels were linked directly to obesity (N=258 triads) and earlier first menstrual periods (N=235 triads) in young adult granddaughters. These associations remained significant independent of body mass index in the second generation. Given obesity and early first menstrual period are risk factors for various cancers, ancestral DDT disruption may lead to higher risk of cancers in the current generation of young adults.

A data source sufficient to examine lung cancer incidence and risk factors by smoking status among Asian American, Native Hawaiian, and Pacific Islander (AANHPI) females has not been available. DeRouen and colleagues describe development of a large, multilevel resource linking electronic health...

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