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Published: 01 March 2024
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Published: 01 March 2024
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Schematic interpretation of results from Dietrich, Trub, and colleagues whe...
Published: 01 March 2024
Figure 1. Schematic interpretation of results from Dietrich, Trub, and colleagues wherein three different cancer types were treated with CDK4/6 inhibitor, the CDK2 inhibitor INX-315, or the combination. HR+ = Hormone Receptor-positive. Figure 1. Schematic interpretation of results from Dietrich, Trub, and colleagues wherein three different cancer types were treated with CDK4/6 inhibitor, the CDK2 inhibitor INX-315, or the combination. HR+ = Hormone Receptor-positive. More about this image found in Schematic interpretation of results from Dietrich, Trub, and colleagues whe...
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Depletion of the RNA helicase DHX9 in SCLC cells activates type I IFN signa...
Published: 01 March 2024
Figure 1. Depletion of the RNA helicase DHX9 in SCLC cells activates type I IFN signaling through sensing of both DNA:RNA hybrids and dsRNA. DHX9 depletion increases R loop formation and dsDNA breaks, activating cGAS:STING sensing of DNA:RNA hybrids and dsDNA in the cytoplasm of SCLC cells. Deplet... More about this image found in Depletion of the RNA helicase DHX9 in SCLC cells activates type I IFN signa...
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Published: 28 February 2024
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Published: 26 February 2024
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Published: 22 February 2024
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