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Lipoprotein Uptake through Glycosaminoglycans Blocks Ferroptosis in Cancer Available to Purchase
June 23, 2025
Major Finding: Uptake of exogenous lipoproteins through glycosaminoglycans protects cancer cells from ferroptosis.
Concept: Lipoproteins inhibit ferroptosis by delivering α-tocopherol, a form of vitamin E, to cancer cells.
Impact: Blockade of glycosaminoglycans induces ferroptosis and represents a novel therapeutic target in cancer.
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