Skip Nav Destination
![]()
You do not currently have access to this content.
A CAF–Epithelial Niche Promotes Immune Evasion in Squamous Cell Carcinoma
April 1, 2025
Major Finding: A cancer-associated fibroblast (CAF)–epithelial cell niche shields squamous cell carcinomas (SCC) from antitumor immune responses.
Concept: Epithelial JAG1–NOTCH1 signaling promotes the transformation of normal fibroblasts into CAFs.
Impact: Assessing epithelial differentiation and stromal-immune alterations may help track SCC progression.
RSS Feeds