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Specialized Fibroblasts Shape T-Cell Environments in Lung Cancer
November 29, 2024
Major Finding: Specialized fibroblasts promote T-cell infiltration and activation in lung tumors.
Concept: Fibroblastic reticular cells provide a scaffold and activating environment for intratumoral CD8+ T-cells
Impact: Promoting interconnected T-cell environments may be an effective treatment strategy for lung cancer.
DOI:https://doi.org/10.1158/2159-8290.CD-RW2024-144
Publisher:American Association for Cancer Research
Article Type:
Research Watch
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