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A More Selective FGFR Inhibitor for Bladder Cancer

November 6, 2024

A new targeted therapy aimed specifically at FGFR3, TYRA-300, is showing preliminary promise in patients with advanced FGFR3-altered bladder cancer. Partial responses have been seen in an ongoing phase I trial, and the drug is much better tolerated than erdafitinib, a pan–FGFR inhibitor and an approved second-line therapeutic option.

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