Skull Bone Marrow Supplies Hybrid Dendritic-Like Neutrophils in Glioblastoma

Major Finding: Glioblastoma cells recruit hybrid dendritic cell–like neutrophils to suppress tumor growth.

Concept: Myeloid precursors from skull marrow differentiate within tumors to promote an antitumor immune response.

Impact: Stimulating neutrophil egress from skull marrow may present a promising treatment strategy for glioblastoma.