Breast Cancer Cells Hijack Neural Signaling During Leptomeningeal Metastasis

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July 2, 2024

Major Finding: Breast cancer cells can metastasize to the leptomeninges (LM) by co-opting neural signaling pathways.

Concept: Cancer cells migrate along blood vessels that connect bone marrow to the LM and hijack neural survival signals.

Impact: This study highlights a mechanism that may be targeted to prevent metastatic dissemination and progression.

DOI:https://doi.org/10.1158/2159-8290.CD-RW2024-091

Article Type: Research Watch

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Breast Cancer Cells Hijack Neural Signaling During Leptomeningeal Metastasis Available to Purchase